Associations between echocardiographic manifestations and bacterial species in patients with infective endocarditis: a cohort study

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: WFRF:(Lundborg M.) > Associations betwee...

LIBRIS Formathandbok (Information om MARC21)

Fältnamn	Indikatorer	Metadata
000		05298naa a2200601 4500
001		oai:gup.ub.gu.se/290684
003		SwePub
008		240528s2019 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:142934439
024	7	a https://gup.ub.gu.se/publication/2906842 URI
024	7	a https://doi.org/10.1186/s12879-019-4682-z2 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1429344392 URI
040		a (SwePub)gud (SwePub)ki
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Damlin, A.u Karolinska Institutet4 aut
245	1 0	a Associations between echocardiographic manifestations and bacterial species in patients with infective endocarditis: a cohort study
264		c 2019-12-16
264	1	b Springer Science and Business Media LLC,c 2019
520		a Background: The diagnosis of infective endocarditis (IE) is based on microbiological analyses and diagnostic imaging of cardiac manifestations. Echocardiography (ECHO) is preferred for visualization of IE-induced cardiac manifestations. We investigated associations between bacterial infections and IE manifestations diagnosed by ECHO. Methods: In this cohort study, data from patients aged 18 years or above, with definite IE admitted at the Karolinska University Hospital between 2008 and 2017 were obtained from Swedish National Registry of Endocarditis. Bacteria registered as pathogen were primarily selected from positive blood culture and for patients with negative blood culture, bacteria found in culture or PCR from postoperative material was registered as pathogen. Patients with negative results from culture or PCR, and patients who did not undergo ECHO during hospital stay, were excluded. IE manifestations diagnosed by ECHO were obtained from the registry. Chi-squared test and two-sided Fisher's exact test was used for comparisons between categorical variables, and student's t test was used for continuous numerical variables. Multivariable analyses were performed using logistic regression. Secular trend analyses were performed using linear regression. Associations and the strength between the variables were estimated using odds ratios (ORs) with 95% confidence intervals (CIs). P < 0.05 was considered significant. Results: The most common bacteria were Staphylococcus aureus (n = 239, 49%) and viridans group streptococci (n = 102, 21%). The most common manifestations were vegetation in the mitral (n = 195, 40%), aortic (n = 190, 39%), and tricuspid valves (n = 108, 22%). Associations were seen between aortic valve vegetations and Enterococcus faecalis among patients with native aortic valves, between mitral valve vegetations and streptococci of group B or viridans group, between tricuspid valve vegetations and S. aureus among patients with intravenous drug abuse, and between perivalvular abscesses as well as cardiovascular implantable electronic device (CIED)-associated IE and coagulase negative staphylococci (all P < 0.05). Conclusions: Associations were found between certain bacterial species and specific ECHO manifestations. Our study contributes to a better understanding of IE manifestations and their underlying bacterial etiology, which pathogens can cause severe infections and might require close follow-up and surgical treatment.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653		a Infective endocarditis
653		a Echocardiography
653		a Heart valves
653		a Diagnostics
653		a Cardiac imaging
653		a health-care professionals
653		a international collaboration
653		a staphylococcus-aureus
653		a antimicrobial therapy
653		a management
653		a diagnosis
653		a complications
653		a guidelines
653		a statement
653		a surgery
653		a Infectious Diseases
700	1	a Westling, K.u Karolinska Institutet4 aut
700	1	a Maret, E.u Karolinska Institutet4 aut
700	1	a Lundborg, C. S.u Karolinska Institutet4 aut
700	1	a Caidahl, Kenneth,d 1949u Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xcaike
700	1	a Eriksson, M. J.4 aut
710	2	a Karolinska Institutetb Institutionen för medicin, avdelningen för molekylär och klinisk medicin4 org
773	0	t BMC Infectious Diseasesd : Springer Science and Business Media LLCg 19q 19x 1471-2334
856	4	u https://bmcinfectdis.biomedcentral.com/track/pdf/10.1186/s12879-019-4682-z
856	4 8	u https://gup.ub.gu.se/publication/290684
856	4 8	u https://doi.org/10.1186/s12879-019-4682-z
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:142934439

Hitta via bibliotek

BMC Infectious Diseases (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...: Damlin, A.; Westling, K.; Maret, E.; Lundborg, C. S.; Caidahl, Kenneth ...; Eriksson, M. J.

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Infektionsmedici ...

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Kardiologi

Artiklar i publikationen: BMC Infectious D ...

Av lärosätet: Göteborgs universitet; Karolinska Institutet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se