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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008020naa a2200757 4500
001oai:DiVA.org:uu-507483
003SwePub
008230707s2023 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:d25f8f9e-0f26-4fd0-9251-59657873cc3c
009oai:DiVA.org:su-229980
009oai:slubar.slu.se:122864
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5074832 URI
024a https://doi.org/10.1016/j.ijheh.2023.1141962 DOI
024a https://lup.lub.lu.se/record/d25f8f9e-0f26-4fd0-9251-59657873cc3c2 URI
024a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-2299802 URI
024a https://res.slu.se/id/publ/1228642 URI
040 a (SwePub)uud (SwePub)lud (SwePub)sud (SwePub)slu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Pineda, Sebastianu Sveriges lantbruksuniversitet,Swedish University of Agricultural Sciences,Institutionen för biomedicin och veterinär folkhälsovetenskap (BVF),Department of Biomedical Science and Veterinary Public Health4 aut
2451 0a Exposure of Swedish adolescents to elements, persistent organic pollutants (POPs), and rapidly excreted substances-The Riksmaten adolescents 2016-17 national survey
264 1b Elsevier,c 2023
338 a electronic2 rdacarrier
520 a Adolescence is a period of significant physiological changes, and likely a sensitive window to chemical exposure. Few nation-wide population-based studies of chemical body burdens in adolescents have been published. In the national dietary survey Riksmaten Adolescents (RMA) 2016-17, over 13 chemical substance groups, including elements, chlorinated/brominated/fluorinated persistent organic pollutants (POPs) were analysed in blood, and in urine metabolites of phthalates/phthalate alternatives, phosphorous flame retardants, polycyclic aromatic hydrocarbons (PAHs), and pesticides, along with bisphenols and biocide/preservative/antioxidant/UV filter substances (N = 1082, ages 11-21). The aim was to characterize the body burdens in a representative population of adolescents in Sweden, and to compare results with human biomonitoring guidance values (HBM-GVs). Cluster analyses and Spearman's rank order correlations suggested that concentrations of substances with known common exposure sources and similar toxicokinetics formed obvious clusters and showed moderate to very strong correlations (r & GE; 0.4). No clusters were formed between substances from different matrices. Geometric mean (GM) concentrations of the substances were generally less than 3-fold different from those observed among adolescents in NHANES (USA 2015-16) and GerES V (Germany 2014-17). Notable exceptions were brominated diphenyl ethers (PBDEs) with >20-fold lower GM concentrations, and the biocide triclosan and ultraviolet (UV) filter benzophenone-3 with >15-fold lower mean concentrations in RMA compared to NHANES. Exceedance of the most conservative HBM-GVs were observed for aluminium (Al, 26% of subjects), perfluorooctanesulfonic acid (PFOS, 19%), perfluorooctanoic acid (PFOA, 12%), lead (Pb, 12%), MBP (dibutyl phthalate metabolite, 4.8%), hexachlorobenzene (HCB, 3.1%) and 3-phenoxybenzoic acid (PBA, pyrethroid metabolite, 2.2%). Males showed a higher proportion of exceedances than females for Pb, HCB and PFOS; otherwise no gender-related differences in exceedances were observed. A higher proportion of males than females had a Hazard Index (HI) of substances with liver and kidney toxicity and neurotoxicity >1. Industrialized countries with similarly high standards of living, with some exceptions, show comparable average body burdens of a variety of toxic chemicals among adolescents from the general population. The exceedances of HBM-GVs and HIs strongly suggests that further efforts to limit chemical exposure are warranted.
650 7a NATURVETENSKAPx Geovetenskap och miljövetenskapx Miljövetenskap0 (SwePub)105022 hsv//swe
650 7a NATURAL SCIENCESx Earth and Related Environmental Sciencesx Environmental Sciences0 (SwePub)105022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Arbetsmedicin och miljömedicin0 (SwePub)303032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Occupational Health and Environmental Health0 (SwePub)303032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
650 7a NATURVETENSKAPx Biologix Biokemi och molekylärbiologi0 (SwePub)106022 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Biochemistry and Molecular Biology0 (SwePub)106022 hsv//eng
653 a Chemical mixtures
653 a Biomonitoring
653 a Pollutants
653 a Neurotoxic
653 a Hazard index
653 a Adolescents
653 a Adolescents
653 a Biomonitoring
653 a Chemical mixtures
653 a Hazard index
653 a Neurotoxic
653 a Pollutants
700a Lignell, Sannau Swedish Natl Food Agcy, Dept Risk & Benefit Assessment, Uppsala, Sweden.4 aut
700a Gyllenhammar, Irinau Swedish Natl Food Agcy, Dept Risk & Benefit Assessment, Uppsala, Sweden.4 aut
700a Lampa, Erik,d 1977-u Uppsala University,Uppsala universitet,Klinisk epidemiologi4 aut0 (Swepub:uu)erila302
700a Benskin, Jonathan P.,d 1981-u Stockholms universitet,Stockholm University,Institutionen för miljövetenskap4 aut0 (Swepub:su)jbens
700a Lundh, Thomasu Lund University,Lunds universitet,Metalund,Annan verksamhet, LTH,Lunds Tekniska Högskola,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Genetisk arbets- och miljömedicin,Forskargrupper vid Lunds universitet,Other operations, LTH,Faculty of Engineering, LTH,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine,Genetic Occupational and Environmental Medicine,Lund University Research Groups4 aut0 (Swepub:lu)ymed-tlu
700a Lindh, Christianu Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)ymed-cli
700a Kiviranta, Hannuu Finnish Inst Hlth & Welf, Dept Hlth Secur, Helsinki, Finland.,Finnish National Institute for Health and Welfare4 aut
700a Glynn, Andersu Sveriges lantbruksuniversitet,Swedish University of Agricultural Sciences,Institutionen för biomedicin och veterinär folkhälsovetenskap (BVF),Department of Biomedical Science and Veterinary Public Health4 aut
710a Swedish University of Agricultural Sciencesb Institutionen för biomedicin och veterinär folkhälsovetenskap (BVF)4 org
710a Sveriges lantbruksuniversitet
773t International journal of hygiene and environmental healthd : Elsevierg 251q 251x 1438-4639x 1618-131X
856u https://doi.org/10.1016/j.ijheh.2023.114196y Fulltext
856u https://uu.diva-portal.org/smash/get/diva2:1781172/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856u http://dx.doi.org/10.1016/j.ijheh.2023.114196x freey FULLTEXT
856u https://pub.epsilon.slu.se/id/eprint/31343/contentsx primaryx Raw objectx freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-507483
8564 8u https://doi.org/10.1016/j.ijheh.2023.114196
8564 8u https://lup.lub.lu.se/record/d25f8f9e-0f26-4fd0-9251-59657873cc3c
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-229980
8564 8u https://res.slu.se/id/publ/122864

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