Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

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Fältnamn	Indikatorer	Metadata
000		07596naa a2201849 4500
001		oai:DiVA.org:uu-337238
003		SwePub
008		171221s2017 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:136001886
009		oai:DiVA.org:umu-137038
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3372382 URI
024	7	a https://doi.org/10.1038/ncomms157242 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1360018862 URI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1370382 URI
040		a (SwePub)uud (SwePub)kid (SwePub)umu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Scelo, Ghislaine4 aut
245	1 0	a Genome-wide association study identifies multiple risk loci for renal cell carcinoma.
264		c 2017-06-09
264	1	b Springer Science and Business Media LLC,c 2017
338		a print2 rdacarrier
520		a Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing scans, totalling 10,784 cases and 20,406 controls of European ancestry. Twenty-four loci were tested in an additional 3,182 cases and 6,301 controls. We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10-10), 3p22.1 (rs67311347, P=2.5 × 10-8), 3q26.2 (rs10936602, P=8.8 × 10-9), 8p21.3 (rs2241261, P=5.8 × 10-9), 10q24.33-q25.1 (rs11813268, P=3.9 × 10-8), 11q22.3 (rs74911261, P=2.1 × 10-10) and 14q24.2 (rs4903064, P=2.2 × 10-24). Expression quantitative trait analyses suggest plausible candidate genes at these regions that may contribute to RCC susceptibility.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng
700	1	a Purdue, Mark P4 aut
700	1	a Brown, Kevin M4 aut
700	1	a Johansson, Mattias4 aut
700	1	a Wang, Zhaoming4 aut
700	1	a Eckel-Passow, Jeanette E4 aut
700	1	a Ye, Yuanqing4 aut
700	1	a Hofmann, Jonathan N4 aut
700	1	a Choi, Jiyeon4 aut
700	1	a Foll, Matthieu4 aut
700	1	a Gaborieau, Valerie4 aut
700	1	a Machiela, Mitchell J4 aut
700	1	a Colli, Leandro M4 aut
700	1	a Li, Peng4 aut
700	1	a Sampson, Joshua N4 aut
700	1	a Abedi-Ardekani, Behnoush4 aut
700	1	a Besse, Celine4 aut
700	1	a Blanche, Helene4 aut
700	1	a Boland, Anne4 aut
700	1	a Burdette, Laurie4 aut
700	1	a Chabrier, Amelie4 aut
700	1	a Durand, Geoffroy4 aut
700	1	a Le Calvez-Kelm, Florence4 aut
700	1	a Prokhortchouk, Egor4 aut
700	1	a Robinot, Nivonirina4 aut
700	1	a Skryabin, Konstantin G4 aut
700	1	a Wozniak, Magdalena B4 aut
700	1	a Yeager, Meredith4 aut
700	1	a Basta-Jovanovic, Gordana4 aut
700	1	a Dzamic, Zoran4 aut
700	1	a Foretova, Lenka4 aut
700	1	a Holcatova, Ivana4 aut
700	1	a Janout, Vladimir4 aut
700	1	a Mates, Dana4 aut
700	1	a Mukeriya, Anush4 aut
700	1	a Rascu, Stefan4 aut
700	1	a Zaridze, David4 aut
700	1	a Bencko, Vladimir4 aut
700	1	a Cybulski, Cezaryu Karolinska Institutet4 aut
700	1	a Fabianova, Eleonora4 aut
700	1	a Jinga, Viorel4 aut
700	1	a Lissowska, Jolanta4 aut
700	1	a Lubinski, Jan4 aut
700	1	a Navratilova, Marie4 aut
700	1	a Rudnai, Peter4 aut
700	1	a Szeszenia-Dabrowska, Neonila4 aut
700	1	a Benhamou, Simone4 aut
700	1	a Cancel-Tassin, Geraldine4 aut
700	1	a Cussenot, Olivier4 aut
700	1	a Baglietto, Laura4 aut
700	1	a Boeing, Heiner4 aut
700	1	a Khaw, Kay-Tee4 aut
700	1	a Weiderpass, Elisabeteu Karolinska Institutet4 aut
700	1	a Ljungberg, Börjeu Umeå universitet,Urologi och andrologi4 aut0 (Swepub:umu)bolj0001
700	1	a Sitaram, Raviprakash T.u Umeå universitet,Urologi och andrologi4 aut0 (Swepub:umu)tura0001
700	1	a Bruinsma, Fiona4 aut
700	1	a Jordan, Susan J4 aut
700	1	a Severi, Gianluca4 aut
700	1	a Winship, Ingrid4 aut
700	1	a Hveem, Kristian4 aut
700	1	a Vatten, Lars J4 aut
700	1	a Fletcher, Tony4 aut
700	1	a Koppova, Kvetoslava4 aut
700	1	a Larsson, Susanna Cu Uppsala universitet,Ortopedi4 aut0 (Swepub:uu)susla720
700	1	a Wolk, Alicjau Karolinska Institutet,Uppsala universitet,Ortopedi4 aut0 (Swepub:uu)alwol516
700	1	a Banks, Rosamonde E4 aut
700	1	a Selby, Peter J4 aut
700	1	a Easton, Douglas F4 aut
700	1	a Pharoah, Paul4 aut
700	1	a Andreotti, Gabriella4 aut
700	1	a Freeman, Laura E Beane4 aut
700	1	a Koutros, Stella4 aut
700	1	a Albanes, Demetrius4 aut
700	1	a Männistö, Satu4 aut
700	1	a Weinstein, Stephanie4 aut
700	1	a Clark, Peter E4 aut
700	1	a Edwards, Todd L4 aut
700	1	a Lipworth, Loren4 aut
700	1	a Gapstur, Susan M4 aut
700	1	a Stevens, Victoria L4 aut
700	1	a Carol, Hallie4 aut
700	1	a Freedman, Matthew L4 aut
700	1	a Pomerantz, Mark M4 aut
700	1	a Cho, Eunyoung4 aut
700	1	a Kraft, Peter4 aut
700	1	a Preston, Mark A4 aut
700	1	a Wilson, Kathryn M4 aut
700	1	a Michael Gaziano, J4 aut
700	1	a Sesso, Howard D4 aut
700	1	a Black, Amanda4 aut
700	1	a Freedman, Neal D4 aut
700	1	a Huang, Wen-Yi4 aut
700	1	a Anema, John G4 aut
700	1	a Kahnoski, Richard J4 aut
700	1	a Lane, Brian R4 aut
700	1	a Noyes, Sabrina L4 aut
700	1	a Petillo, David4 aut
700	1	a Teh, Bin Tean4 aut
700	1	a Peters, Ulrike4 aut
700	1	a White, Emily4 aut
700	1	a Anderson, Garnet L4 aut
700	1	a Johnson, Lisa4 aut
700	1	a Luo, Juhua4 aut
700	1	a Buring, Julie4 aut
700	1	a Lee, I-Min4 aut
700	1	a Chow, Wong-Ho4 aut
700	1	a Moore, Lee E4 aut
700	1	a Wood, Christopher4 aut
700	1	a Eisen, Timothy4 aut
700	1	a Henrion, Marc4 aut
700	1	a Larkin, James4 aut
700	1	a Barman, Poulami4 aut
700	1	a Leibovich, Bradley C4 aut
700	1	a Choueiri, Toni K4 aut
700	1	a Mark Lathrop, G4 aut
700	1	a Rothman, Nathaniel4 aut
700	1	a Deleuze, Jean-Francois4 aut
700	1	a McKay, James D4 aut
700	1	a Parker, Alexander S4 aut
700	1	a Wu, Xifeng4 aut
700	1	a Houlston, Richard S4 aut
700	1	a Brennan, Paul4 aut
700	1	a Chanock, Stephen J4 aut
710	2	a Karolinska Institutetb Urologi och andrologi4 org
773	0	t Nature Communicationsd : Springer Science and Business Media LLCg 8q 8x 2041-1723
856	4	u https://www.nature.com/articles/ncomms15724.pdf
856	4	u https://umu.diva-portal.org/smash/get/diva2:1117165/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-337238
856	4 8	u https://doi.org/10.1038/ncomms15724
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:136001886
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-137038

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Av författaren/redakt...: Scelo, Ghislaine; Purdue, Mark P; Brown, Kevin M; Johansson, Matti ...; Wang, Zhaoming; Eckel-Passow, Je ...; visa fler...; Ye, Yuanqing; Hofmann, Jonatha ...; Choi, Jiyeon; Foll, Matthieu; Gaborieau, Valer ...; Machiela, Mitche ...; Colli, Leandro M; Li, Peng; Sampson, Joshua ...; Abedi-Ardekani, ...; Besse, Celine; Blanche, Helene; Boland, Anne; Burdette, Laurie; Chabrier, Amelie; Durand, Geoffroy; Le Calvez-Kelm, ...; Prokhortchouk, E ...; Robinot, Nivonir ...; Skryabin, Konsta ...; Wozniak, Magdale ...; Yeager, Meredith; Basta-Jovanovic, ...; Dzamic, Zoran; Foretova, Lenka; Holcatova, Ivana; Janout, Vladimir; Mates, Dana; Mukeriya, Anush; Rascu, Stefan; Zaridze, David; Bencko, Vladimir; Cybulski, Cezary; Fabianova, Eleon ...; Jinga, Viorel; Lissowska, Jolan ...; Lubinski, Jan; Navratilova, Mar ...; Rudnai, Peter; Szeszenia-Dabrow ...; Benhamou, Simone; Cancel-Tassin, G ...; Cussenot, Olivie ...; Baglietto, Laura; Boeing, Heiner; Khaw, Kay-Tee; Weiderpass, Elis ...; Ljungberg, Börje; Sitaram, Ravipra ...; Bruinsma, Fiona; Jordan, Susan J; Severi, Gianluca; Winship, Ingrid; Hveem, Kristian; Vatten, Lars J; Fletcher, Tony; Koppova, Kvetosl ...; Larsson, Susanna ...; Wolk, Alicja; Banks, Rosamonde ...; Selby, Peter J; Easton, Douglas ...; Pharoah, Paul; Andreotti, Gabri ...; Freeman, Laura E ...; Koutros, Stella; Albanes, Demetri ...; Männistö, Satu; Weinstein, Steph ...; Clark, Peter E; Edwards, Todd L; Lipworth, Loren; Gapstur, Susan M; Stevens, Victori ...; Carol, Hallie; Freedman, Matthe ...; Pomerantz, Mark ...; Cho, Eunyoung; Kraft, Peter; Preston, Mark A; Wilson, Kathryn ...; Michael Gaziano, ...; Sesso, Howard D; Black, Amanda; Freedman, Neal D; Huang, Wen-Yi; Anema, John G; Kahnoski, Richar ...; Lane, Brian R; Noyes, Sabrina L; Petillo, David; Teh, Bin Tean; Peters, Ulrike; White, Emily; Anderson, Garnet ...; Johnson, Lisa; Luo, Juhua; Buring, Julie; Lee, I-Min; Chow, Wong-Ho; Moore, Lee E; Wood, Christophe ...; Eisen, Timothy; Henrion, Marc; Larkin, James; Barman, Poulami; Leibovich, Bradl ...; Choueiri, Toni K; Mark Lathrop, G; Rothman, Nathani ...; Deleuze, Jean-Fr ...; McKay, James D; Parker, Alexande ...; Wu, Xifeng; Houlston, Richar ...; Brennan, Paul; Chanock, Stephen ...; visa färre...

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