Multiple medicine use: factors of importance in different age groups

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Multiple medicine use: factors of importance in different age groups

Moen, Janne, 1980- (författare): Uppsala universitet,Institutionen för farmaci,Pharmaceutical Outcomes Research Group

Antonov, Karolina (författare): The Swedish Association of the Pharmaceutical Industry,Pharmaceutical Outcomes Research Group

Larsson, Charlotte A. (författare): Department of Clinical Sciences, Lund University

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Lindblad, Ulf (författare): Department of Public Health and Community Medicine/Primary Health Care, The Sahlgrenska Academy at Gothenburg University and The Skaraborg Institute

Nilsson, J. Lars G. (författare): The NEPI Foundation

Råstam, Lennart (författare): Department of Clinical Sciences, Lund University

Ring, Lena (författare): Uppsala universitet,Institutionen för farmaci,Pharmaceutical Outcomes Research Group

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(creator_code:org_t)

Engelska.

Relaterad länk:: https://urn.kb.se/re...

Annan publikation (övrigt vetenskapligt/konstnärligt)

Abstract Ämnesord

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BACKGROUND: Multiple medicine use among elderly persons is likely to be the result of treatment regimens developed over a long time. By learning more about this development, it might be possible to increase quality in management of multiple medicine use across the adult lifespan. OBJECTIVE: To describe patterns of multiple medicine use in a general population in association with sociodemographic factors, lifestyle, and health status. METHODS: Data from a cross-sectional population health survey collected during 2001-2005 in 2,816 randomly selected Swedish residents (age 30-75 years; response rate 76%). Multiple medicine use was defined as the upper quartile in each age cohort. RESULTS: The cut-offs defining multiple medicine use were: ≥2 for 30-49 year olds, ≥3 for 50-64 year olds, and ≥5 for 65-75 year olds. When drugs were classified into the second level of the ATC code, 76.3% of the 30-49 year olds, 97.9% of the 50-64 year olds, and 100% of the 65-75 year olds used a unique combination of drugs. The multivariate analyses showed that diabetes and poor self-rated health were associated with multiple medicine use in all age cohorts. Female gender and hypertension were associated with multiple medicine use among 30-49 and 50-64 year olds, ex-smoking among 50-64 year olds, and obesity among 65-75 year olds. CONCLUSIONS: Different cut-offs should be used in defining multiple medicine use in different age groups. A vast majority of users of multiple medicines have a unique drug combination. Multiple medicine use is associated with morbidity and poor self-rated health across all age groups, suggesting that multiple medicine use is not due to drug over-consumption.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Samhällsfarmaci och klinisk farmaci (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Social and Clinical Pharmacy (hsv//eng)

Nyckelord

health status factors
lifestyle factors
multiple medicine use
polypharmacy
population survey
self-rated health
sociodemographic factors
Community pharmacy services
Samhällsfarmaci

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Av författaren/redakt...: Moen, Janne, 198 ...; Antonov, Karolin ...; Larsson, Charlot ...; Lindblad, Ulf; Nilsson, J. Lars ...; Råstam, Lennart; visa fler...; Ring, Lena; visa färre...

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Av lärosätet: Uppsala universitet

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