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Effects of amide local anaesthetics on eicosanoid formation in burned skin.

Jönsson, Anders, 1959 (author)
Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för ortopedi,Institute of Surgical Sciences, Department of Orthopaedics
Cassuto, Jean (author)
Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för anestesiologi och intensivvård,Institute of Surgical Sciences, Department of Anaesthesiology and Intensive Care
Tarnow, Peter, 1963 (author)
Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för plastikkirurgi,Institute of Surgical Sciences, Department of Plastic Surgery
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Sinclair, Robert, 1951 (author)
Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för anestesiologi och intensivvård,Institute of Surgical Sciences, Department of Anaesthesiology and Intensive Care
Bennett, A (author)
Tavares, I A (author)
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 (creator_code:org_t)
1999
1999
English.
In: Acta anaesthesiologica Scandinavica. - 0001-5172. ; 43:6, s. 618-22
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Previous studies have demonstrated potent inhibition of burn oedema and progressive ischaemia by local anaesthetics. Since eicosanoids have been suggested to play an important role in the pathophysiology of burns, we compared in the present ex vivo study the effects of topical lidocaine/prilocaine cream (EMLA, ASTRA, Sweden) and intravenous lidocaine with that of saline on eicosanoid formation by normal and burned rat skin.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)

Keyword

6-Ketoprostaglandin F1 alpha
biosynthesis
Administration
Topical
Anesthetics
Local
pharmacology
Animals
Burns
metabolism
Eicosanoids
biosynthesis
Infusions
Intravenous
Lidocaine
administration & dosage
pharmacology
Male
Ointments
Prilocaine
administration & dosage
pharmacology
Rats
Rats
Sprague-Dawley
Skin
drug effects
metabolism
Thromboxane B2
biosynthesis

Publication and Content Type

ref (subject category)
art (subject category)

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