WFRF:(Edgren H.)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04278naa a2200457 4500 | |
| 001 | oai:DiVA.org:uu-358267 | |
| 003 | SwePub | |
| 008 | 180829s2018 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:138569435 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3582672 URI |
| 024 | 7 | a https://doi.org/10.1111/joim.127622 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1385694352 URI |
| 040 | a (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Edgren, G.u Karolinska Institutet4 aut |
| 245 | 1 0 | a Searching for unknown transfusion-transmitted hepatitis viruses :b a binational cohort study of 1.5 million transfused patients |
| 264 | c 2018-04-25 | |
| 264 | 1 | b WILEY,c 2018 |
| 338 | a print2 rdacarrier | |
| 520 | a Background. Both hepatitis B and C viruses were transmitted through blood transfusion before implementation of donor screening. The existence of additional, yet unknown transfusion transmittable agents causing liver disease could have important public health implications.Methods. Analyses were based on the Scandinavian Donations and Transfusions (SCANDAT2) database. Cox regression models were used to estimate the hazard ratio (HR) of developing chronic liver disease in recipients of blood from donors who later developed any chronic liver disease compared to recipients who received blood transfusion from healthy donors. We also studied whether the risk of liver disease was increased in patients who received units from high-risk' donors, defined as donors who had a higher than expected occurrence of liver disease amongst their previous recipients. All analyses were stratified before and after 1992 to account for the effect of screening for hepatitis C virus.Results. A total of 1 482 922 transfused patients were included in the analyses. Analyses showed evidence of transfusion transmission of liver diseases before, but not after the implementation of hepatitis C virus screening in 1992, with HRs for any liver disease of 1.38 [95% confidence interval (CI), 1.30-1.46] and 0.99 (95% CI, 0.91-1.07), before and after 1992, respectively. Similarly, blood components from 'high-risk' donors conferred increased risks before, but not after 1992.Conclusions. Our data provide no evidence for transfusion transmission of agents causing liver disease after the implementation of screening for hepatitis B and C, and suggest that if such transmission does occur, it is rare. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng |
| 653 | a hepatitis | |
| 653 | a transfusion medicine | |
| 700 | 1 | a Hjalgrim, H.u Statens Serum Inst, Dept Epidemiol Res, Copenhagen, Denmark;Copenhagen Univ Hosp, Dept Hematol, Copenhagen, Denmark4 aut |
| 700 | 1 | a Rostgaard, K.u Statens Serum Inst, Dept Epidemiol Res, Copenhagen, Denmark4 aut |
| 700 | 1 | a Dahl, V.u Publ Hlth Agcy Sweden, Dept Monitoring & Evaluat, Stockholm, Sweden4 aut |
| 700 | 1 | a Titlestad, K.u Odense Univ Hosp, Dept Clin Immunol, Odense, Denmark4 aut |
| 700 | 1 | a Erikstrup, C.u Aarhus Univ Hosp, Dept Clin Immunol, Aarhus, Denmark4 aut |
| 700 | 1 | a Wikman, A.u Karolinska Institutet4 aut |
| 700 | 1 | a Norda, Rutu Uppsala universitet,Klinisk immunologi4 aut0 (Swepub:uu)runor498 |
| 700 | 1 | a Majeed, A.u Karolinska Inst, Dept Med Epidemiol & Biostat, Box 281, SE-17177 Stockholm, Sweden;Alfred Hlth, Dept Gastroenterol, Melbourne, Vic, Australia;Monash Univ, Cent Clin Sch, Melbourne, Vic, Australia4 aut |
| 710 | 2 | a Karolinska Institutetb Statens Serum Inst, Dept Epidemiol Res, Copenhagen, Denmark;Copenhagen Univ Hosp, Dept Hematol, Copenhagen, Denmark4 org |
| 773 | 0 | t Journal of Internal Medicined : WILEYg 284:1, s. 92-103q 284:1<92-103x 0954-6820x 1365-2796 |
| 856 | 4 | u https://findresearcher.sdu.dk:8443/ws/files/142980926/S_FHOAM2.PDF |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-358267 |
| 856 | 4 8 | u https://doi.org/10.1111/joim.12762 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:138569435 |
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