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FältnamnIndikatorerMetadata
00006661naa a2200541 4500
001oai:gup.ub.gu.se/299056
003SwePub
008240910s2021 | |||||||||||000 ||eng|
009oai:DiVA.org:umu-184277
009oai:prod.swepub.kib.ki.se:146277771
009oai:DiVA.org:liu-174343
009oai:DiVA.org:uu-442109
0247 a https://gup.ub.gu.se/publication/2990562 URI
0247 a https://doi.org/10.1016/j.hpb.2020.07.0102 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1842772 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1462777712 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1743432 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4421092 URI
040 a (SwePub)gud (SwePub)umud (SwePub)kid (SwePub)liud (SwePub)uu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Sternby Eilard, Malin,d 1974u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery,Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Transplantation, Sahlgrenska University Hospital, Gothenburg, Sweden,Univ Gothenburg, Dept Surg, Inst Clin Sci, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Dept Transplantat, Gothenburg, Sweden.4 aut
2451 0a Survival and prognostic factors after transplantation, resection and ablation in a national cohort of early hepatocellular carcinoma
264 1b Elsevier BV,c 2021
520 a © 2020 International Hepato-Pancreato-Biliary Association Inc. Background: In patients with early hepatocellular cancer (HCC) and preserved liver function, the choice between transplantation, resection and ablation and which factors to consider is not obvious and guidelines differ. In this national cohort study, we aimed to compare posttreatment survival in patients fulfilling predefined criteria, and to analyse preoperative risk factors that could influence decision. Methods: We used data from HCC-patients registered with primary transplantation, resection or ablation 2008–2016 in the SweLiv-registry. In Child A-subgroups, 18–75 years, we compared survival after transplantation or resection, with different tumour criteria; either corresponding to our transplantation criteria (N = 257) or stricter with single tumours ≤50 mm (N = 159). A subgroup with single tumours ≤30 mm, compared all three treatments (N = 193). Results: We included 1022 HCC-patients; transplantation n = 223, resection n = 438, ablation n = 361. In the transplant criteria subgroup, differences in five-year survival, adjusted for age and gender, were not significant, with 71.2% (CI 62.3–81.3) after transplantation (n = 109) and 63.5% (CI 54.9–73.5) after resection (n = 148). Good liver function (Child 5 vs. 6, Albumin ≥36), increased the risk after transplantation, but decreased the risk after resection and ablation. Conclusion: Even within Child A, detailed liver function assessment is important before treatment decision, and for stratifying survival comparisons.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
7001 a Naredi, Peter,d 1955u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery,Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden,Univ Gothenburg, Dept Surg, Inst Clin Sci, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Dept Surg, Gothenburg, Sweden.4 aut0 (Swepub:gu)xnarpe
7001 a Helmersson, Madeleineu Regional Cancer Center West, Western Sweden Health Care Region, Gothenburg, Sweden,Reg Canc Ctr West, Western Sweden Hlth Care Reg, Gothenburg, Sweden.4 aut
7001 a Hemmingsson, Oskar,d 1975-u Umeå universitet,Kirurgi,Department of Surgical and Perioperative Sciences, Umeå University, Sweden,Umeå Univ, Dept Surg & Perioperat Sci, S-90187 Umeå, Sweden.4 aut0 (Swepub:umu)osrhen96
7001 a Isaksson, Bengtu Uppsala universitet,Gastrointestinalkirurgi4 aut0 (Swepub:uu)benis326
7001 a Lindell, Gertu Department of Surgery, Skåne University Hospital, Lund, Sweden,Skane Univ Hosp, Dept Surg, Lund, Sweden.4 aut
7001 a Sandström, Peru Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US,Linköping Univ, Fac Hlth Sci, Cty Council Ostergotland, Dept Clin & Expt Med,Dept Surg, Linköping, Sweden.4 aut0 (Swepub:liu)persa07
7001 a Strömberg, Ceciliau Karolinska Institutet,Division of Surgery, Department of Clinical Science, Intervention and Technology, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden,Karolinska Inst, Dept Clin Sci Intervent & Technol, Div Surg, Stockholm, Sweden.;Karolinska Univ Hosp, Stockholm, Sweden.4 aut
7001 a Rizell, Magnus,d 1963u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery,Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden; Department of Transplantation, Sahlgrenska University Hospital, Gothenburg, Sweden,Univ Gothenburg, Dept Surg, Inst Clin Sci, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Dept Transplantat, Gothenburg, Sweden.4 aut0 (Swepub:gu)xrizma
7102 a Göteborgs universitetb Institutionen för kliniska vetenskaper, Avdelningen för kirurgi4 org
7730 t HPBd : Elsevier BVg 23:3, s. 394-403q 23:3<394-403x 1365-182Xx 1477-2574
8564 u http://www.hpbonline.org/article/S1365182X20311035/pdf
8564 8u https://gup.ub.gu.se/publication/299056
8564 8u https://doi.org/10.1016/j.hpb.2020.07.010
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-184277
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:146277771
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-174343
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-442109

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