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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005241naa a2200793 4500
001oai:DiVA.org:umu-68470
003SwePub
008130422s2013 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:e6bb62e5-8580-4654-9ba7-e127c1bc16cf
024a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-684702 URI
024a https://doi.org/10.2337/dc12-10202 DOI
024a https://lup.lub.lu.se/record/37650042 URI
040 a (SwePub)umud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Brand, Judith S.4 aut
2451 0a Age at Menopause, Reproductive Life Span, and Type 2 Diabetes Risk
264 c 2013-03-14
264 1b American Diabetes Association,c 2013
338 a print2 rdacarrier
520 a OBJECTIVE-Age at menopause is an important determinant of future health outcomes, but little is known about its relationship with type 2 diabetes. We examined the associations of menopausal age and reproductive life span (menopausal age minus menarcheal age) with diabetes risk.RESEARCH DESIGN AND METHODS-Data were obtained from the InterAct study, a prospective case-cohort study nested within the European Prospective Investigation into Cancer and Nutrition. A total of 3,691 postmenopausal type 2 diabetic case subjects and 4,408 subcohort members were included in the analysis, with a median follow-up of 11 years. Prentice weighted Cox proportional hazards models were adjusted for age, known risk factors for diabetes, and reproductive factors, and effect modification by BMI, waist circumference, and smoking was studied.RESULTS-Mean (SD) age of the subcohort was 59.2 (5.8) years. After multivariable adjustment, hazard ratios (HRs) of type 2 diabetes were 1.32 (95% CI 1.04-1.69), 1.09 (0.90-1.31), 0.97 (0.86-1.10), and 0.85 (0.70-1.03) for women with menopause at ages <40, 40-44, 45-49, and >= 55 years, respectively, relative to those with menopause at age 50-54 years. The HR per SD younger age at menopause was 1.08 (1.02-1.14). Similarly, a shorter reproductive life span was associated with a higher diabetes risk (HR per SD lower reproductive life span 1.06 [ 1.01-1.12]). No effect modification by BMI, waist circumference, or smoking was observed (P interaction all > 0.05).CONCLUSIONS-Early menopause is associated with a greater risk of type 2 diabetes. Diabetes Care 36:1012-1019, 2013
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng
700a van der Schouw, Yvonne T.4 aut
700a Onland-Moret, N. Charlotte4 aut
700a Sharp, Stephen J.4 aut
700a Ong, Ken K.4 aut
700a Khaw, Kay-Tee4 aut
700a Ardanaz, Eva4 aut
700a Amiano, Pilar4 aut
700a Boeing, Heiner4 aut
700a Chirlaque, Maria-Dolores4 aut
700a Clavel-Chapelon, Francoise4 aut
700a Crowe, Francesca L.4 aut
700a de Lauzon-Guillain, Blandine4 aut
700a Duell, Eric J.4 aut
700a Fagherazzi, Guy4 aut
700a Franks, Paul W.u Lund University,Lunds universitet,Umeå universitet,Medicin,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)med-plf
700a Grioni, Sara4 aut
700a Groop, Leifu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)endo-lgr
700a Kaaks, Rudolf4 aut
700a Key, Timothy J.4 aut
700a Nilsson, Peteru Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-pni
700a Overvad, Kim4 aut
700a Palli, Domenico4 aut
700a Panico, Salvatore4 aut
700a Quiros, J. Ramon4 aut
700a Rolandsson, Olovu Umeå universitet,Allmänmedicin4 aut0 (Swepub:umu)olro0005
700a Sacerdote, Carlotta4 aut
700a Sanchez, Maria-Jose4 aut
700a Slimani, Nadia4 aut
700a Teucher, Birgit4 aut
700a Tjonneland, Anne4 aut
700a Tumino, Rosario4 aut
700a van der A, Daphne L.4 aut
700a Feskens, Edith J. M.4 aut
700a Langenberg, Claudia4 aut
700a Forouhi, Nita G.4 aut
700a Riboli, Elio4 aut
700a Wareham, Nicholas J.4 aut
710a Umeå universitetb Medicin4 org
773t Diabetes Cared : American Diabetes Associationg 36:4, s. 1012-1019q 36:4<1012-1019x 0149-5992x 1935-5548
856u https://care.diabetesjournals.org/content/diacare/36/4/1012.full.pdf
856u http://dx.doi.org/10.2337/dc12-1020y FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-68470
8564 8u https://doi.org/10.2337/dc12-1020
8564 8u https://lup.lub.lu.se/record/3765004

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