Sökning: WFRF:(Palli J.) > Age at Menopause, R...
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000 | 05241naa a2200793 4500 | |
001 | oai:DiVA.org:umu-68470 | |
003 | SwePub | |
008 | 130422s2013 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:e6bb62e5-8580-4654-9ba7-e127c1bc16cf | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-684702 URI |
024 | 7 | a https://doi.org/10.2337/dc12-10202 DOI |
024 | 7 | a https://lup.lub.lu.se/record/37650042 URI |
040 | a (SwePub)umud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Brand, Judith S.4 aut |
245 | 1 0 | a Age at Menopause, Reproductive Life Span, and Type 2 Diabetes Risk |
264 | c 2013-03-14 | |
264 | 1 | b American Diabetes Association,c 2013 |
338 | a print2 rdacarrier | |
520 | a OBJECTIVE-Age at menopause is an important determinant of future health outcomes, but little is known about its relationship with type 2 diabetes. We examined the associations of menopausal age and reproductive life span (menopausal age minus menarcheal age) with diabetes risk.RESEARCH DESIGN AND METHODS-Data were obtained from the InterAct study, a prospective case-cohort study nested within the European Prospective Investigation into Cancer and Nutrition. A total of 3,691 postmenopausal type 2 diabetic case subjects and 4,408 subcohort members were included in the analysis, with a median follow-up of 11 years. Prentice weighted Cox proportional hazards models were adjusted for age, known risk factors for diabetes, and reproductive factors, and effect modification by BMI, waist circumference, and smoking was studied.RESULTS-Mean (SD) age of the subcohort was 59.2 (5.8) years. After multivariable adjustment, hazard ratios (HRs) of type 2 diabetes were 1.32 (95% CI 1.04-1.69), 1.09 (0.90-1.31), 0.97 (0.86-1.10), and 0.85 (0.70-1.03) for women with menopause at ages <40, 40-44, 45-49, and >= 55 years, respectively, relative to those with menopause at age 50-54 years. The HR per SD younger age at menopause was 1.08 (1.02-1.14). Similarly, a shorter reproductive life span was associated with a higher diabetes risk (HR per SD lower reproductive life span 1.06 [ 1.01-1.12]). No effect modification by BMI, waist circumference, or smoking was observed (P interaction all > 0.05).CONCLUSIONS-Early menopause is associated with a greater risk of type 2 diabetes. Diabetes Care 36:1012-1019, 2013 | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
700 | 1 | a van der Schouw, Yvonne T.4 aut |
700 | 1 | a Onland-Moret, N. Charlotte4 aut |
700 | 1 | a Sharp, Stephen J.4 aut |
700 | 1 | a Ong, Ken K.4 aut |
700 | 1 | a Khaw, Kay-Tee4 aut |
700 | 1 | a Ardanaz, Eva4 aut |
700 | 1 | a Amiano, Pilar4 aut |
700 | 1 | a Boeing, Heiner4 aut |
700 | 1 | a Chirlaque, Maria-Dolores4 aut |
700 | 1 | a Clavel-Chapelon, Francoise4 aut |
700 | 1 | a Crowe, Francesca L.4 aut |
700 | 1 | a de Lauzon-Guillain, Blandine4 aut |
700 | 1 | a Duell, Eric J.4 aut |
700 | 1 | a Fagherazzi, Guy4 aut |
700 | 1 | a Franks, Paul W.u Lund University,Lunds universitet,Umeå universitet,Medicin,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)med-plf |
700 | 1 | a Grioni, Sara4 aut |
700 | 1 | a Groop, Leifu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)endo-lgr |
700 | 1 | a Kaaks, Rudolf4 aut |
700 | 1 | a Key, Timothy J.4 aut |
700 | 1 | a Nilsson, Peteru Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-pni |
700 | 1 | a Overvad, Kim4 aut |
700 | 1 | a Palli, Domenico4 aut |
700 | 1 | a Panico, Salvatore4 aut |
700 | 1 | a Quiros, J. Ramon4 aut |
700 | 1 | a Rolandsson, Olovu Umeå universitet,Allmänmedicin4 aut0 (Swepub:umu)olro0005 |
700 | 1 | a Sacerdote, Carlotta4 aut |
700 | 1 | a Sanchez, Maria-Jose4 aut |
700 | 1 | a Slimani, Nadia4 aut |
700 | 1 | a Teucher, Birgit4 aut |
700 | 1 | a Tjonneland, Anne4 aut |
700 | 1 | a Tumino, Rosario4 aut |
700 | 1 | a van der A, Daphne L.4 aut |
700 | 1 | a Feskens, Edith J. M.4 aut |
700 | 1 | a Langenberg, Claudia4 aut |
700 | 1 | a Forouhi, Nita G.4 aut |
700 | 1 | a Riboli, Elio4 aut |
700 | 1 | a Wareham, Nicholas J.4 aut |
710 | 2 | a Umeå universitetb Medicin4 org |
773 | 0 | t Diabetes Cared : American Diabetes Associationg 36:4, s. 1012-1019q 36:4<1012-1019x 0149-5992x 1935-5548 |
856 | 4 | u https://care.diabetesjournals.org/content/diacare/36/4/1012.full.pdf |
856 | 4 | u http://dx.doi.org/10.2337/dc12-1020y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-68470 |
856 | 4 8 | u https://doi.org/10.2337/dc12-1020 |
856 | 4 8 | u https://lup.lub.lu.se/record/3765004 |
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