WFRF:(Austin Peter C.)
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General and specific contextual effects in multilevel regression analyses and their paradoxical relationship : A conceptual tutorial
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- Merlo, Juan (author)
- Lund University,Lunds universitet,Socialepidemiologi,Forskargrupper vid Lunds universitet,Social Epidemiology,Lund University Research Groups,Center for Primary Health Care Research
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- Wagner, Philippe (author)
- Uppsala University,Lund University,Lunds universitet,Uppsala universitet,Centrum för klinisk forskning, Västerås,Lund Univ, Fac Med, Dept Clin Sci, Unit Social Epidemiol,CRC, Jan Waldenstroms St 35, SE-21421 Malmo, Sweden.,Socialepidemiologi,Forskargrupper vid Lunds universitet,Social Epidemiology,Lund University Research Groups
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- Austin, Peter C. (author)
- Inst Clin Evaluat Sci, Toronto, ON, Canada.,Institute for Clinical Evaluative Sciences (ICES)
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- Elsevier, 2018
- 2018
- English.
- In: SSM - Population Health. - : Elsevier. - 2352-8273. ; 5, s. 33-37
- Journal article (peer-reviewed)
Abstract
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- To be relevant for public health, a context (e.g., neighborhood, school, hospital) should influence or affect the health status of the individuals included in it. The greater the influence of the shared context, the higher the correlation of subject outcomes within that context is likely to be. This intra-context or intra-class correlation is of substantive interest and has been used to quantify the magnitude of the general contextual effect (GCE). Furthermore, ignoring the intra-class correlation in a regression analysis results in spuriously narrow 95% confidence intervals around the estimated regression coefficients of the specific contextual variables entered as covariates and, thereby, overestimates the precision of the estimated specific contextual effects (SCEs). Multilevel regression analysis is an appropriate methodology for investigating both GCEs and SCEs. However, frequently researchers only report SCEs and disregard the study of the GCE, unaware that small GCEs lead to more precise estimates of SCEs so, paradoxically, the less relevant the context is, the easier it is to detect (and publish) small but "statistically significant" SCEs. We describe this paradoxical situation and encourage researchers performing multilevel regression analysis to consider simultaneously both the GCE and SCEs when interpreting contextual influences on individual health.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
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