Sökning: WFRF:(Isenberg D. A.) > Use of combined hor...
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000 | 07134naa a2200913 4500 | |
001 | oai:lup.lub.lu.se:fc4cf98c-a54e-419c-a74b-ea4a9a2c2f5b | |
003 | SwePub | |
008 | 190722s2019 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:141287995 | |
024 | 7 | a https://lup.lub.lu.se/record/fc4cf98c-a54e-419c-a74b-ea4a9a2c2f5b2 URI |
024 | 7 | a https://doi.org/10.1093/rheumatology/kez0142 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1412879952 URI |
040 | a (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Mendel, Arielleu McGill University Health Center4 aut |
245 | 1 0 | a Use of combined hormonal contraceptives among women with systemic lupus erythematosus with and without medical contraindications to oestrogen |
264 | c 2019-02-08 | |
264 | 1 | b Oxford University Press (OUP),c 2019 |
300 | a 9 s. | |
520 | a Objectives. To assess the prevalence of combined hormonal contraceptives (CHCs) in reproductive-age women with SLE with and without possible contraindications and to determine factors associated with their use in the presence of possible contraindications. Methods. This observational cohort study included premenopausal women ages 18-45 years enrolled in the SLICC Registry ≤15 months after SLE onset, with annual assessments spanning 2000-2017. World Health Organization Category 3 or 4 contraindications to CHCs (e.g. hypertension, aPL) were assessed at each study visit. High disease activity (SLEDAI score >12 or use of >0.5 mg/kg/day of prednisone) was considered a relative contraindication. Results. A total of 927 SLE women contributed 6315 visits, of which 3811 (60%) occurred in the presence of one or more possible contraindication to CHCs. Women used CHCs during 512 (8%) visits, of which 281 (55%) took place in the setting of one or more possible contraindication. The most frequently observed contraindications were aPL (52%), hypertension (34%) and migraine with aura (22%). Women with one or more contraindication were slightly less likely to be taking CHCs [7% of visits (95% CI 7, 8)] than women with no contraindications [9% (95% CI 8, 10)]. Conclusion. CHC use was low compared with general population estimates (>35%) and more than half of CHC users had at least one possible contraindication. Many yet unmeasured factors, including patient preferences, may have contributed to these observations. Further work should also aim to clarify outcomes associated with this exposure. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng |
653 | a Anti-phospholipid syndrome | |
653 | a Contraception | |
653 | a Epidemiology | |
653 | a Systemic lupus erythematosus | |
700 | 1 | a Bernatsky, Sashau McGill University Health Center4 aut |
700 | 1 | a Pineau, Christian A.u McGill University Health Center4 aut |
700 | 1 | a St-Pierre, Yvanu McGill University Health Center4 aut |
700 | 1 | a Hanly, John G.u Dalhousie University4 aut |
700 | 1 | a Urowitz, Murray B.u Toronto Western Hospital,University of Toronto4 aut |
700 | 1 | a Clarke, Ann E.u University of Calgary4 aut |
700 | 1 | a Romero-Diaz, Juanitau Instituto Nacional de Ciencias Médicas y Nutrición4 aut |
700 | 1 | a Gordon, Carolineu University of Birmingham,City Hospital, Birmingham4 aut |
700 | 1 | a Bae, Sang Cheolu Hanyang University4 aut |
700 | 1 | a Wallace, Daniel J.u Cedars-Sinai Medical Center,University of California, Los Angeles4 aut |
700 | 1 | a Merrill, Joan T.u Oklahoma Medical Research Foundation4 aut |
700 | 1 | a Buyon, Jillu New York University4 aut |
700 | 1 | a Isenberg, David A.u University College London4 aut |
700 | 1 | a Rahman, Anisuru University College London4 aut |
700 | 1 | a Ginzler, Ellen M.u SUNY Downstate Health Sciences University4 aut |
700 | 1 | a Petri, Michelleu Johns Hopkins University School of Medicine4 aut |
700 | 1 | a Dooley, Mary Anneu University of North Carolina4 aut |
700 | 1 | a Fortin, Paulu Centre hospitalier universitaire de Québec4 aut |
700 | 1 | a Gladman, Dafna D.u Toronto Western Hospital,University of Toronto4 aut |
700 | 1 | a Steinsson, Kristjánu National University Hospital of Iceland4 aut |
700 | 1 | a Ramsey-Goldman, Rosalindu Northwestern University Feinberg School of Medicine4 aut |
700 | 1 | a Khamashta, Munther A.u University College London4 aut |
700 | 1 | a Aranow, Cynthiau Feinstein Institute for Medical Research4 aut |
700 | 1 | a MacKay, Megganu Feinstein Institute for Medical Research4 aut |
700 | 1 | a Alarcón, Gracielau University of Alabama4 aut |
700 | 1 | a Manzi, Susanu Allegheny Health Network4 aut |
700 | 1 | a Nived, Olau Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)reum-oni |
700 | 1 | a Jönsen, Andreasu Lund University,Lunds universitet,Lund SLE Research Group,Forskargrupper vid Lunds universitet,Lund University Research Groups4 aut0 (Swepub:lu)reum-ajo |
700 | 1 | a Zoma, Asad A.u Hairmyres Hospital4 aut |
700 | 1 | a Van Vollenhoven, Ronald F.u Karolinska Institutet,Karolinska Institute4 aut |
700 | 1 | a Ramos-Casals, Manuelu Hospital Clínic of Barcelona4 aut |
700 | 1 | a Ruiz-Irastorza, Giuillermou University of the Basque Country4 aut |
700 | 1 | a Lim, Samu Emory University4 aut |
700 | 1 | a Kalunian, Kenneth C.u University of California, San Diego4 aut |
700 | 1 | a Inanc, Muratu Istanbul University4 aut |
700 | 1 | a Kamen, Diane L.u Medical University of South Carolina4 aut |
700 | 1 | a Peschken, Christine A.u University of Manitoba4 aut |
700 | 1 | a Jacobsen, Sørenu Copenhagen University Hospital,University of Copenhagen4 aut |
700 | 1 | a Askanase, Ancau Columbia University4 aut |
700 | 1 | a Sanchez-Guerrero, Jorgeu University of Toronto,Mount Sinai Hospital of University of Toronto4 aut |
700 | 1 | a Bruce, Ian N.u University of Manchester,Manchester University NHS Foundation Trust4 aut |
700 | 1 | a Costedoat-Chalumeau, Nathalieu Cochin Hospital4 aut |
700 | 1 | a Vinet, Evelyneu McGill University Health Center4 aut |
710 | 2 | a McGill University Health Centerb Dalhousie University4 org |
773 | 0 | t Rheumatology (United Kingdom)d : Oxford University Press (OUP)g 58:7, s. 1259-1267q 58:7<1259-1267x 1462-0324x 1462-0332 |
856 | 4 | u http://dx.doi.org/10.1093/rheumatology/kez014y FULLTEXT |
856 | 4 | u https://europepmc.org/articles/pmc6821299?pdf=render |
856 | 4 8 | u https://lup.lub.lu.se/record/fc4cf98c-a54e-419c-a74b-ea4a9a2c2f5b |
856 | 4 8 | u https://doi.org/10.1093/rheumatology/kez014 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:141287995 |
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