One-minute and five-minute Apgar scores and child developmental health at 5 years of age: a population-based cohort study in British Columbia, Canada

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Fältnamn	Indikatorer	Metadata
000		03229naa a2200325 4500
001		oai:prod.swepub.kib.ki.se:141128737
003		SwePub
008		240701s2019 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1411287372 URI
024	7	a https://doi.org/10.1136/bmjopen-2018-0276552 DOI
040		a (SwePub)ki
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Razaz, Nu Karolinska Institutet4 aut
245	1 0	a One-minute and five-minute Apgar scores and child developmental health at 5 years of age: a population-based cohort study in British Columbia, Canada
264		c 2019-05-09
264	1	b BMJ,c 2019
520		a We investigated the associations between Apgar scores at 1 and 5 min, across the entire range of score values, and child developmental health at 5 years of age.SettingBritish Columbia, CanadaParticipantsAll singleton term infants without major congenital anomalies born between 1993 and 2009, who had a developmental assessment in kindergarten between 1999 and 2014.Main outcomes and measuresDevelopmental vulnerability on one or more domains of the Early Development Instrument and special needs requirements. Adjusted rate ratios (aRRs) and 95% CIs were estimated using log-linear regression.ResultsOf the 150 081 children in the study, 45 334 (30.2%) were developmentally vulnerable and 3644 (2.5%) had special needs. There was an increasing trend in developmental vulnerability and special needs with decreasing 1 min and 5 min Apgar scores. Compared with children with an Apgar score of 10 at 5 min, the aRR for developmental vulnerability increased steadily with decreasing Apgar score from 1.02 (95% CI 1.00 to 1.04) for an Apgar score of 9 to 1.57 (95% CI 1.03 to 2.39) for an Apgar score of 2. Among children with 1 min Apgar scores in the 7–10 range, changes in Apgar scores between 1 and 5 min were associated with significant differences in developmental vulnerability. Compared with children who had an Apgar score of 9 at 1 min and 10 at 5 min, children with an Apgar score of 9 at both 1 and 5 min had higher rates of developmental vulnerability (aRR 1.03, 95% CI 1.01 to 1.05). Compared with infants with an Apgar of 10 at both 1 and 5 min, infants with a 1 min score of 10 and a 5 min score of <10 had higher rates of developmental vulnerability (aRR 1.53, 95% CI 1.08 to 2.17).ConclusionRisks of adverse developmental health and having special needs at 5 years of age are inversely associated with 1 min and 5 min Apgar scores across their entire range.
700	1	a Cnattingius, Su Karolinska Institutet4 aut
700	1	a Persson, Mu Karolinska Institutet4 aut
700	1	a Tedroff, Ku Karolinska Institutet4 aut
700	1	a Lisonkova, S4 aut
700	1	a Joseph, KS4 aut
710	2	a Karolinska Institutet4 org
773	0	t BMJ opend : BMJg 9:5, s. e027655-q 9:5<e027655-x 2044-6055
856	4	u https://bmjopen.bmj.com/content/bmjopen/9/5/e027655.full.pdf
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:141128737
856	4 8	u https://doi.org/10.1136/bmjopen-2018-027655

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Av författaren/redakt...: Razaz, N; Cnattingius, S; Persson, M; Tedroff, K; Lisonkova, S; Joseph, KS

Artiklar i publikationen: BMJ open

Av lärosätet: Karolinska Institutet

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