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Aortic regurgitatio...
Aortic regurgitation management : A systematic review of clinical practice guidelines and recommendations
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- Galusko, Victor (author)
- King's College Hospital
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- Thornton, George (author)
- Barts Health NHS Trust,University College London
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- Jozsa, Csilla (author)
- Newham University Hospital,Barts Health NHS Trust
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- Sekar, Baskar (author)
- Gloucestershire Hospitals NHS Foundation Trust
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- Aktuerk, Dincer (author)
- Barts Health NHS Trust
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- Treibel, Thomas A. (author)
- Barts Health NHS Trust,University College London
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- Petersen, Steffen E. (author)
- Queen Mary University,Barts Health NHS Trust
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- Ionescu, Adrian (author)
- Morriston Hospital
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- Ricci, Fabrizio (author)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Casa di Cura Villa Serena,University G.d'Annunzio of Chieti-Pescara
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- Khanji, Mohammed Y. (author)
- Newham University Hospital,Barts Health NHS Trust,Queen Mary University
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(creator_code:org_t)
- 2022-01-13
- 2022
- English 14 s.
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In: European Heart Journal - Quality of Care and Clinical Outcomes. - : Oxford University Press (OUP). - 2058-5225 .- 2058-1742. ; 8:2, s. 113-126
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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Abstract
Subject headings
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- Guidelines for the diagnosis and management of aortic regurgitation (AR) contain recommendations that do not always match. We systematically reviewed clinical practice guidelines and summarized similarities and differences in the recommendations as well as gaps in evidence on the management of AR. We searched MEDLINE and Embase (1 January 2011 to 1 September 2021), Google Scholar, and websites of relevant organizations for contemporary guidelines that were rigorously developed as assessed by the Appraisal of Guidelines for Research and Evaluation II tool. Three guidelines met our inclusion criteria. There was consensus on the definition of severe AR and use of echocardiography and of multimodality imaging for diagnosis, with emphasis on comprehensive assessment by the heart valve team to assess suitability and choice of intervention. Surgery is indicated in all symptomatic patients and aortic valve replacement is the cornerstone of treatment. There is consistency in the frequency of follow-up of patients, and safety of non-cardiac surgery in patients without indications for surgery. Discrepancies exist in recommendations for 3D imaging and the use of global longitudinal strain and biomarkers. Cut-offs for left ventricular ejection fraction and size for recommending surgery in severe asymptomatic AR also vary. There are no specific AR cut-offs for high-risk surgery and the role of percutaneous intervention is yet undefined. Recommendations on the treatment of mixed valvular disease are sparse and lack robust prospective data.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Aortic regurgitation
- Aortic valve
- Guidelines
- Systematic review
- Valvular heart disease
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- ref (subject category)
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- By the author/editor
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Galusko, Victor
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Thornton, George
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Jozsa, Csilla
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Sekar, Baskar
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Aktuerk, Dincer
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Treibel, Thomas ...
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show more...
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Petersen, Steffe ...
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Ionescu, Adrian
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Ricci, Fabrizio
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Khanji, Mohammed ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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European Heart J ...
- By the university
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Lund University