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Circulating Levels ...
Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses
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- Murphy, Neil (författare)
- Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France,Int Agcy Res Canc, Sect Nutr & Metab, Lyon, France.
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- Carreras-Torres, Robert (författare)
- Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain,Bellvitge Biomed Res Inst IDIBELL, ONCOBELL Program, Colorectal Canc Grp, Barcelona, Spain.
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- Song, Mingyang (författare)
- Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, MA, Boston, United States; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, MA, Boston, United States; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States; Department of Nutrition, Harvard T.H. Chan School of Public Health, MA, Boston, United States,Massachusetts Gen Hosp, Div Gastroenterol, Boston, MA 02114 USA.;Harvard Med Sch, Boston, MA 02115 USA.;Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA.
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- Chan, Andrew T. (författare)
- Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, MA, Boston, United States; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, MA, Boston, United States; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, MA, Boston, United States,Massachusetts Gen Hosp, Div Gastroenterol, Boston, MA 02114 USA.;Harvard Med Sch, Boston, MA 02115 USA.;Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA.
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- Martin, Richard M. (författare)
- MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom; Bristol Medical School, Department of Population Health Sciences, University of Bristol, Bristol, United Kingdom; National Institute for Health Research (NIHR) Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and the University of Bristol, Bristol, United Kingdom
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- Papadimitriou, Nikos (författare)
- Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France
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- Dimou, Niki (författare)
- Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France
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- Tsilidis, Konstantinos K. (författare)
- Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom,Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, Ioannina, Greece.
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- Banbury, Barbara (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States,Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA. Univ Hosp Bristol NHS Fdn Trust, Bristol, Avon, England.;Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1124 Columbia St, Seattle, WA 98104 USA.
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- Bradbury, Kathryn E. (författare)
- National Institute for Health Innovation, School of Population Health, The University of Auckland, Auckland, New Zealand,Univ Auckland, Sch Populat Hlth, Natl Inst Hlth Innovat, Auckland, New Zealand.
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- Besevic, Jelena (författare)
- Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom,Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA. Univ Hosp Bristol NHS Fdn Trust, Bristol, Avon, England.;Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, Ioannina, Greece.;Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.
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- Rinaldi, Sabina (författare)
- Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France
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- Riboli, Elio (författare)
- Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.
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- Cross, Amanda J. (författare)
- Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom,Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.
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- Travis, Ruth C. (författare)
- Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom,Univ Oxford, Nuffield Dept Populat Hlth, Canc Epidemiol Unit, Oxford, England.
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- Agnoli, Claudia (författare)
- Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy,Ist Nazl Tumori, Fdn IRCCS, Epidemiol & Prevent Unit, Milan, Italy.
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- Albanes, Demetrius (författare)
- Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States,NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA.;NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA.;NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA.;NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA.;NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA.
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- Berndt, Sonja I. (författare)
- Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States
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- Bézieau, Stéphane (författare)
- Service de Génétique Médicale, Centre Hospitalier Universitaire (CHU) Nantes, Nantes, France
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- Bishop, D. Timothy (författare)
- Institute of Medical Research at St. James's, University of Leeds, Leeds, United Kingdom,Univ Leeds, Inst Med Res St Jamess, Leeds, W Yorkshire, England.
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- Brenner, Hermann (författare)
- Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany,German Canc Res Ctr, Div Clin Epidemiol, Heidelberg, Germany.;German Canc Res Ctr, Div Clin Epidemiol, Heidelberg, Germany. Natl Ctr Tumor Dis NCT, Heidelberg, Germany.
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- Buchanan, Daniel D. (författare)
- Colorectal Oncogenomics Group, Department of Clinical Pathology, The University of Melbourne, Victoria, Parkville, Australia; University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, Victoria, Parkville, Australia; Genetic Medicine and Family Cancer Clinic, The Royal Melbourne Hospital, Victoria, Parkville, Australia,Univ Melbourne, Dept Clin Pathol, Colorectal Oncogenom Grp, Parkville, Vic 3010, Australia.;Univ Melbourne, Ctr Canc Res, Victorian Comprehens Canc Ctr, Parkville, Vic 3010, Australia.;Royal Melbourne Hosp, Genet Med & Family Canc Clin, Parkville, Vic, Australia.
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- Onland-Moret, N. Charlotte (författare)
- Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands,Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.;Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.;Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.;Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.
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- Burnett-Hartman, Andrea (författare)
- Institute for Health Research, Kaiser Permanente Colorado, CO, Denver, United States
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- Campbell, Peter T. (författare)
- Behavioral and Epidemiology Research Group, American Cancer Society, Georgia, Atlanta, Georgia
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- Casey, Graham (författare)
- Center for Public Health Genomics, University of Virginia, VA, Charlottesville, United States
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- Castellví-Bel, Sergi (författare)
- Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), University of Barcelona, Barcelona, Spain
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- Chang-Claude, Jenny (författare)
- Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
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- Chirlaque, María-Dolores (författare)
- Department of Epidemiology, Regional Health Council, IMIB-Arrixaca, Murcia University, Murcia, Spain; CIBER in Epidemiology and Public Health (CIBERESP), Madrid, Spain
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- de la Chapelle, Albert (författare)
- Department of Cancer Biology and Genetics and the Comprehensive Cancer Center, The Ohio State University, OH, Columbus, United States
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- English, Dallas (författare)
- Cancer Epidemiology Division, Cancer Council Victoria, Victoria, Melbourne, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Melbourne, Australia
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- Figueiredo, Jane C. (författare)
- Department of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, CA, Los Angeles, United States
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- Gallinger, Steven J. (författare)
- Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Ontario, Toronto, Canada
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- Giles, Graham G. (författare)
- Cancer Epidemiology Division, Cancer Council Victoria, Victoria, Melbourne, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Melbourne, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Victoria, Clayton, Australia
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- Gruber, Stephen B. (författare)
- Department of Preventive Medicine & USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States
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- Gsur, Andrea (författare)
- Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria
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- Hampe, Jochen (författare)
- Department of Medicine I, University Hospital Dresden, Technische Universität Dresden (TU Dresden), Dresden, Germany,Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA. Univ Hosp Bristol NHS Fdn Trust, Bristol, Avon, England.
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- Hampel, Heather (författare)
- Division of Human Genetics, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, OH, Columbus, United States
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- Harrison, Tabitha A. (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States,Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA. Univ Hosp Bristol NHS Fdn Trust, Bristol, Avon, England.
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- Hoffmeister, Michael (författare)
- Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany,Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA. Univ Hosp Bristol NHS Fdn Trust, Bristol, Avon, England.
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- Hsu, Li (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Department of Biostatistics, University of Washington, WA, Seattle, United States
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- Huang, Wen-Yi (författare)
- Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States
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- Huyghe, Jeroen R. (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States
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- Jenkins, Mark A. (författare)
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Melbourne, Australia
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- Keku, Temitope O. (författare)
- Center for Gastrointestinal Biology and Disease, University of North Carolina, NC, Chapel Hill, United States
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- Kühn, Tilman (författare)
- Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
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- Kweon, Sun-Seog (författare)
- Department of Preventive Medicine, Chonnam National University Medical School, Korea, Gwangju, South Korea; Jeonnam Regional Cancer Center, Chonnam National University Hwasun Hospital, Korea, Hwasun, South Korea
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- Le Marchand, Loic (författare)
- University of Hawaii Cancer Center, HI, Honolulu, United States
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- Li, Christopher I. (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States
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- Li, Li (författare)
- Department of Family Medicine, University of Virginia, VA, Charlottesville, United States
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- Lindblom, Annika (författare)
- Karolinska Institutet
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- Martín, Vicente (författare)
- CIBER in Epidemiology and Public Health (CIBERESP), Madrid, Spain; Biomedicine Institute (IBIOMED), University of León, León, Spain
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- Milne, Roger L. (författare)
- Cancer Epidemiology Division, Cancer Council Victoria, Victoria, Melbourne, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Melbourne, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Victoria, Clayton, Australia
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- Moreno, Victor (författare)
- Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain; CIBER in Epidemiology and Public Health (CIBERESP), Madrid, Spain; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain
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- Newcomb, Polly A. (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; School of Public Health, University of Washington, WA, Seattle, United States
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- Offit, Kenneth (författare)
- Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, NY, New York, United States; Department of Medicine, Weill Cornell Medical College, NY, New York, United States
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- Ogino, Shuji (författare)
- Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, MA, Boston, United States; Cancer Immunology and Cancer Epidemiology Programs, Dana-Farber Harvard Cancer Center, MA, Boston, United States; Broad Institute of MIT and Harvard, MA, Cambridge, United States
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- Ose, Jennifer (författare)
- Huntsman Cancer Institute and Department of Population Health Sciences, University of Utah, UT, Salt Lake City, United States
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- Perduca, Vittorio (författare)
- CESP (Inserm U1018), Fac. de médecine - Université Paris-Saclay, Fac. de médecine - UVSQ, Villejuif, France; Gustave Roussy, Villejuif, France; Laboratoire de Mathématiques Appliquées MAP5 (UMR CNRS 8145), Université Paris Descartes, France
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- Phipps, Amanda I. (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Department of Epidemiology, University of Washington, WA, Seattle, United States
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- Platz, Elizabeth A. (författare)
- Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD, Baltimore, United States
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- Potter, John D. (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Centre for Public Health Research, Massey University, Wellington, New Zealand
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- Qu, Conghui (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States
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- Rennert, Gad (författare)
- Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
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- Sakoda, Lori C. (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Division of Research, Kaiser Permanente Northern California, CA, Oakland, United States
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- Schafmayer, Clemens (författare)
- Department of General and Thoracic Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
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- Schoen, Robert E. (författare)
- Department of Medicine and Epidemiology, University of Pittsburgh Medical Center, PA, Pittsburgh, United States
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- Slattery, Martha L. (författare)
- Department of Internal Medicine, University of Utah, UT, Salt Lake City, United States
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- Tangen, Catherine M. (författare)
- SWOG Statistical Center, Fred Hutchinson Cancer Research Center, WA, Seattle, United States
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- Ulrich, Cornelia M. (författare)
- Huntsman Cancer Institute and Department of Population Health Sciences, University of Utah, UT, Salt Lake City, United States
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- van Duijnhoven, Franzel J.B. (författare)
- Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, Netherlands
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- van Guelpen, Bethany (författare)
- Umeå universitet,Wallenberg centrum för molekylär medicin vid Umeå universitet (WCMM),Onkologi
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- Visvanathan, Kala (författare)
- Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD, Baltimore, United States
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- Vodicka, Pavel (författare)
- Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic
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- Vodickova, Ludmila (författare)
- Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic
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- Vymetalkova, Veronika (författare)
- Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic
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- Wang, Hansong (författare)
- University of Hawaii Cancer Center, HI, Honolulu, United States
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- White, Emily (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Department of Epidemiology, University of Washington, WA, Seattle, United States
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- Wolk, Alicja (författare)
- Karolinska Institutet
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- Woods, Michael O. (författare)
- Memorial University of Newfoundland, Discipline of Genetics, St. John's, Canada
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- Wu, Anna H. (författare)
- University of Southern California, Preventive Medicine, CA, Los Angeles, United States
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- Zheng, Wei (författare)
- Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, TN, Nashville, United States
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- Peters, Ulrike (författare)
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Department of Epidemiology, University of Washington, WA, Seattle, United States
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- Gunter, Marc J. (författare)
- Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France,Int Agcy Res Canc, Sect Nutr & Metab, Lyon, France.
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Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France Int Agcy Res Canc, Sect Nutr & Metab, Lyon, France (creator_code:org_t)
- Elsevier BV, 2020
- 2020
- Engelska.
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Ingår i: Gastroenterology. - : Elsevier BV. - 0016-5085 .- 1528-0012. ; 158:5, s. 1300-1312.e20
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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http://www.gastrojou...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background & Aims: Human studies examining associations between circulating levels of insulin-like growth factor 1 (IGF1) and insulin-like growth factor binding protein 3 (IGFBP3) and colorectal cancer risk have reported inconsistent results. We conducted complementary serologic and Mendelian randomization (MR) analyses to determine whether alterations in circulating levels of IGF1 or IGFBP3 are associated with colorectal cancer development.Methods: Serum levels of IGF1 were measured in blood samples collected from 397,380 participants from the UK Biobank, from 2006 through 2010. Incident cancer cases and cancer cases recorded first in death certificates were identified through linkage to national cancer and death registries. Complete follow-up was available through March 31, 2016. For the MR analyses, we identified genetic variants associated with circulating levels of IGF1 and IGFBP3. The association of these genetic variants with colorectal cancer was examined with 2-sample MR methods using genome-wide association study consortia data (52,865 cases with colorectal cancer and 46,287 individuals without [controls])Results: After a median follow-up period of 7.1 years, 2665 cases of colorectal cancer were recorded. In a multivariable-adjusted model, circulating level of IGF1 associated with colorectal cancer risk (hazard ratio per 1 standard deviation increment of IGF1, 1.11; 95% confidence interval [CI] 1.05–1.17). Similar associations were found by sex, follow-up time, and tumor subsite. In the MR analyses, a 1 standard deviation increment in IGF1 level, predicted based on genetic factors, was associated with a higher risk of colorectal cancer risk (odds ratio 1.08; 95% CI 1.03–1.12; P = 3.3 × 10–4). Level of IGFBP3, predicted based on genetic factors, was associated with colorectal cancer risk (odds ratio per 1 standard deviation increment, 1.12; 95% CI 1.06–1.18; P = 4.2 × 10–5). Colorectal cancer risk was associated with only 1 variant in the IGFBP3 gene region (rs11977526), which also associated with anthropometric traits and circulating level of IGF2.Conclusions: In an analysis of blood samples from almost 400,000 participants in the UK Biobank, we found an association between circulating level of IGF1 and colorectal cancer. Using genetic data from 52,865 cases with colorectal cancer and 46,287 controls, a higher level of IGF1, determined by genetic factors, was associated with colorectal cancer. Further studies are needed to determine how this signaling pathway might contribute to colorectal carcinogenesis.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medical Genetics (hsv//eng)
Nyckelord
- CRC
- GWAS
- Risk Factors
- Signal Transduction
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Murphy, Neil
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Carreras-Torres, ...
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Song, Mingyang
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Chan, Andrew T.
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Martin, Richard ...
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Papadimitriou, N ...
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Dimou, Niki
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Tsilidis, Konsta ...
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Banbury, Barbara
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Bradbury, Kathry ...
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Besevic, Jelena
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Rinaldi, Sabina
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Riboli, Elio
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Cross, Amanda J.
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Travis, Ruth C.
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Agnoli, Claudia
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Albanes, Demetri ...
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Berndt, Sonja I.
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Bézieau, Stéphan ...
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Bishop, D. Timot ...
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Brenner, Hermann
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Buchanan, Daniel ...
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Onland-Moret, N. ...
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Burnett-Hartman, ...
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Campbell, Peter ...
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Casey, Graham
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Castellví-Bel, S ...
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Chang-Claude, Je ...
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Chirlaque, María ...
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de la Chapelle, ...
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English, Dallas
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Figueiredo, Jane ...
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Gallinger, Steve ...
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Giles, Graham G.
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Gruber, Stephen ...
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Gsur, Andrea
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Hampe, Jochen
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Hampel, Heather
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Harrison, Tabith ...
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Hoffmeister, Mic ...
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Hsu, Li
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Huang, Wen-Yi
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Huyghe, Jeroen R ...
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Jenkins, Mark A.
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Keku, Temitope O ...
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Kühn, Tilman
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Kweon, Sun-Seog
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Le Marchand, Loi ...
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Li, Christopher ...
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Li, Li
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Lindblom, Annika
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Martín, Vicente
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Milne, Roger L.
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Moreno, Victor
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Newcomb, Polly A ...
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Offit, Kenneth
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Ogino, Shuji
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Ose, Jennifer
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Perduca, Vittori ...
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Phipps, Amanda I ...
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Platz, Elizabeth ...
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Potter, John D.
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Qu, Conghui
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Rennert, Gad
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Sakoda, Lori C.
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Schafmayer, Clem ...
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Schoen, Robert E ...
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Slattery, Martha ...
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Tangen, Catherin ...
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Ulrich, Cornelia ...
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van Duijnhoven, ...
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van Guelpen, Bet ...
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Visvanathan, Kal ...
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Vodicka, Pavel
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Vodickova, Ludmi ...
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Vymetalkova, Ver ...
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Wang, Hansong
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White, Emily
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Wolk, Alicja
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Woods, Michael O ...
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Wu, Anna H.
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Zheng, Wei
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Peters, Ulrike
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Gunter, Marc J.
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Gastroenterology
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Umeå universitet
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Uppsala universitet
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Karolinska Institutet