Suboptimal Control of Lipid Levels: Results from 29 Countries Participating in the Centralized Pan-Regional Surveys on the Undertreatment of Hypercholesterolaemia (CEPHEUS)

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: WFRF:(Abdulla M) > Suboptimal Control ...

Suboptimal Control of Lipid Levels : Results from 29 Countries Participating in the Centralized Pan-Regional Surveys on the Undertreatment of Hypercholesterolaemia (CEPHEUS)

Chiang, Chern-En (author): Taipei Vet Gen Hosp, Div Cardiol, Gen Clin Res Ctr, Taipei, Taiwan.;Natl Yang Ming Univ, Taipei 112, Taiwan.

Ferrieres, Jean (author): Toulouse Univ Hosp, Dept Cardiol, Toulouse, France.

Gotcheva, Nina N. (author): Natl Heart Hosp, Dept Cardiol, Sofia, Bulgaria.

Raal, Frederick J. (author): Johannesburg Hosp, Fac Hlth Sci, Johannesburg, South Africa.

Shehab, Abdulla (author): United Arab Emirates Univ, Dept Internal Med, Al Ain, U Arab Emirates.

Sung, Jidong (author): Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Seoul, South Korea.

Henriksson, Karin M. (author): Uppsala universitet,Kardiovaskulär epidemiologi,AstraZeneca Gothenburg, Mölndal, Sweden.

Hermans, Michel P. (author): Clin Univ St Luc, Endocrinol & Nutr, B-1200 Brussels, Belgium.

show less...

Taipei Vet Gen Hosp, Div Cardiol, Gen Clin Res Ctr, Taipei, Taiwan;Natl Yang Ming Univ, Taipei 112, Taiwan. Toulouse Univ Hosp, Dept Cardiol, Toulouse, France. (creator_code:org_t)

Japan Atherosclerosis Society, 2016
2016
English.
In: Journal of Atherosclerosis and Thrombosis. - : Japan Atherosclerosis Society. - 1880-3873 .- 1340-3478. ; 23:5, s. 567-587

Related links:: https://www.jstage.j...; show more...; https://urn.kb.se/re...; https://doi.org/10.5...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

Aim: Five multicentre, cross-sectional Centralized Pan-Regional Surveys on the Undertreatment of Hypercholesterolaemia (CEPHEUS) were conducted in 29 countries across Asia, Western Europe, Eastern Europe, the Middle East, and Africa. The surveys assessed the current use and efficacy of lipid-lowering drugs (LLDs) worldwide and identified possible patient and physician characteristics associated with failure to attain low-density lipoprotein cholesterol (LDL-C) goals. The aim of this analysis was to consolidate the global results from these surveys. Methods: The surveys involved patients aged >= 18 years who had been prescribed LLDs for at least 3 months without dose changes for at least 6 weeks. A single visit was scheduled for data collection, including fasting plasma lipid and glucose levels. Cardiovascular risk profile and LDL-C goal attainment were assessed according to the 2004 updated US National Cholesterol Education Program Adult Treatment Panel III guidelines. Results: In total, 35 121 patients (mean age: 60.4 years) were included, and 90.3% had been prescribed statin monotherapy. Overall, only 49.4% of patients reached their recommended LDL-C level. LDL-C goals were attained in 54.8% (5084/9273) and 22.8% (3287/14 429) of patients were at high and very high cardiovascular risk, respectively. Factors associated with an increased likelihood of LDL-C goal attainment were lower baseline cardiovascular risk; presence of diabetes mellitus, hypertension, or history of cardiovascular disease; and treatment with simvastatin, atorvastatin, or rosuvastatin (vs. all other LLDs). Conclusion: LDL-C goal attainment in patients taking LLDs is suboptimal worldwide, particularly in patients at high and very high cardiovascular risk.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Keyword

Cardiovascular disease
Hypercholesterolaemia
Lipidlowering drugs
Low-density lipoprotein cholesterol
Undertreatment

Publication and Content Type

ref (subject category)
art (subject category)

Find in a library

Journal of Atherosclerosis and Thrombosis (Search for host publication in LIBRIS)

To the university's database

Find more in SwePub

By the author/editor: Chiang, Chern-En; Ferrieres, Jean; Gotcheva, Nina N ...; Raal, Frederick ...; Shehab, Abdulla; Sung, Jidong; show more...; Henriksson, Kari ...; Hermans, Michel ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cardiac and Card ...

Articles in the publication: Journal of Ather ...

By the university: Uppsala University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se