AMNE:(ENGINEERING AND TECHNOLOGY Industrial Biotechnology Bioenergy)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04065naa a2200373 4500 | |
| 001 | oai:research.chalmers.se:1bf8d16b-e53b-42c3-a905-f966f5accf3c | |
| 003 | SwePub | |
| 008 | 171008s2013 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://research.chalmers.se/publication/1769092 URI |
| 040 | a (SwePub)cth | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a kon2 swepub-publicationtype |
| 072 | 7 | a vet2 swepub-contenttype |
| 100 | 1 | a Bettiga, Maurizio,d 1978u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)bettiga |
| 245 | 1 0 | a Robust S. cerevisiae strain for next generation bio-processes: concepts and case-studies |
| 264 | 1 | c 2013 |
| 520 | a The realization of an oil independent economy relies on the development of competitive processes for the production of fuels and chemicals from renewable resources. The extensive research on second-generation ethanol has paved the way to a new concept of bio-based industry, where lignocellulosic material is the primary source of sugars, to be converted to a number of fuels and chemicals. Sugars are released from cellulose and hemicellulose by pretreatment and hydrolysis steps. Harsh conditions result in the formation of a number of compounds, originating from sugars and lignin breakdown and acting as microorganism inhibitors. Weak organic acids, furaldehydes and phenolic compounds are sources of stress for the fermenting microorganism, as they influence cellular metabolism in a number of ways, including direct damage on cellular functions or by perturbations of the cellular energy and redox metabolism. In addition, the product of interest can act as a potent inhibitor. Regardless of the product, robust microorganisms are a prerequisite for the feasibility of lignocellulose-based bioprocesses.Current research carried out by our group focuses on the yeast Saccharomyces cerevisiae and aims at investigating the molecular bases of microbial robustness. Our efforts include the identification of the molecular targets of different classes of fermentation inhibitors aiming at understanding the complex responses of the cells to these compounds. The final goal is to engineer more robust strains. The concept of robustness will be discussed and examples of key features for S. cerevisiae robustness as well as examples of successful engineering to increase robustness will be presented. | |
| 650 | 7 | a TEKNIK OCH TEKNOLOGIERx Industriell bioteknik0 (SwePub)2092 hsv//swe |
| 650 | 7 | a ENGINEERING AND TECHNOLOGYx Industrial Biotechnology0 (SwePub)2092 hsv//eng |
| 650 | 7 | a NATURVETENSKAPx Biologix Biokemi och molekylärbiologi0 (SwePub)106022 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Biochemistry and Molecular Biology0 (SwePub)106022 hsv//eng |
| 650 | 7 | a TEKNIK OCH TEKNOLOGIERx Industriell bioteknikx Bioenergi0 (SwePub)209042 hsv//swe |
| 650 | 7 | a ENGINEERING AND TECHNOLOGYx Industrial Biotechnologyx Bioenergy0 (SwePub)209042 hsv//eng |
| 650 | 7 | a TEKNIK OCH TEKNOLOGIERx Industriell bioteknikx Annan industriell bioteknik0 (SwePub)209992 hsv//swe |
| 650 | 7 | a ENGINEERING AND TECHNOLOGYx Industrial Biotechnologyx Other Industrial Biotechnology0 (SwePub)209992 hsv//eng |
| 700 | 1 | a Ask, Magnus,d 1983u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)bt02asma |
| 700 | 1 | a Mapelli, Valeria,d 1978u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)mapelli |
| 700 | 1 | a Adeboye, Peter,d 1982u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)adeboye |
| 700 | 1 | a Lindberg, Lina,d 1984u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)linali |
| 700 | 1 | a Olsson, Lisbeth,d 1963u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)lisbetho |
| 710 | 2 | a Chalmers tekniska högskola4 org |
| 773 | 0 | t 35th Symposium on Biotechnology for Fuels and Chemicals (Portland, OR. April 29-May 2, 2013) |
| 856 | 4 8 | u https://research.chalmers.se/publication/176909 |
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