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Intimate partner vi...
Intimate partner violence is associated with cytomegalovirus among young women in rural South Africa : An HPTN 068 analysis
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- Kelly, Nicole K. (författare)
- Department of Epidemiology, University of North Carolina, Chapel Hill, United States
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- Gómez-Olivé, F. Xavier (författare)
- MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, South Africa
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- Wagner, L. Danielle (författare)
- Women’s Global Health Imperative, RTI International, Berkeley, United States
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- Aiello, Allison E. (författare)
- Department of Epidemiology, Robert N Butler Columbia Aging Center, Mailman School of Public Health, Columbia University, New York, United States
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- Kahn, Kathleen (författare)
- Umeå universitet,Institutionen för epidemiologi och global hälsa,Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
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- Pettifor, Audrey (författare)
- Department of Epidemiology, University of North Carolina, Chapel Hill, United States; MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, South Africa
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- Stoner, Marie C.D. (författare)
- Women’s Global Health Imperative, RTI International, Berkeley, United States
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(creator_code:org_t)
- Routledge, 2023
- 2023
- Engelska.
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Ingår i: Global Public Health. - : Routledge. - 1744-1692 .- 1744-1706. ; 18:1
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Stressful life circumstances (e.g. violence and poverty) have been associated with elevated biomarkers, including C-reactive protein (CRP), cytomegalovirus (CMV), and herpes simplex virus type-1 (HSV-1), among older adults in high-income settings. Yet, it remains unknown whether these relationships exist among younger populations in resource-limited settings. We therefore utilised a cohort of 1,279 adolescent girls and young women (AGYW) from the HIV Prevention Trials Network 068 study in rural South Africa to examine the associations between 6 hypothesized stressors (intimate partner violence (IPV), food insecurity, depression, socioeconomic status (SES), HIV, childhood violence) and 3 biomarkers that were measured using dried blood spots (CRP, CMV, and HSV-1). Ordinal logistic regression estimated the lagged and cross-sectional associations between each stressor and each biomarker. IPV was cross-sectionally associated with elevated CMV (OR = 2.45, 95% CI = 1.05,5.72), while low SES was cross-sectionally associated with reduced CMV (OR = 0.73, 95% CI = 0.58,0.93). AGYW with HIV had elevated biomarkers cross-sectionally (CRP: OR = 1.51, 95% CI = 1.08,2.09; CMV: OR = 1.86, 95% CI = 1.31,2.63; HSV-1: OR = 1.68, 95% CI = 1.17,2.41) and in a lagged analysis. The association between violence and CMV could help explain how violence results in stress and subsequently worse health among AGYW; however, additional research is needed to disentangle the longitudinal nature of IPV and stress.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- adolescent girls and young women
- biomarkers
- cytomegalovirus
- intimate partner violence
- South Africa
- Stress
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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