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WFRF:(Lopez Jose Manuel)
 

Sökning: WFRF:(Lopez Jose Manuel) > Anisakis simplex-se...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003108naa a2200337 4500
001oai:lup.lub.lu.se:2fe0661b-08ac-43f3-9db1-3d63b0b70ce2
003SwePub
008160404s2001 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/11199842 URI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Gracia-Bara, Maria T4 aut
2451 0a Anisakis simplex-sensitized patients: should fish be excluded from their diet?
264 1c 2001
520 a BACKGROUND: Anisakis simplex (A.s.) allergy is an emerging disease. The third-stage larvae of this nematode are a source of hidden allergens in fish. There are no clear guidelines concerning dietary restrictions for patients with serum-specific IgE to this parasite. OBJECTIVE: To follow up the clinical data and immunological parameters of patients sensitized to A.s. during 6 to 23 months. METHODS: The clinical symptoms and serologic status of 17 patients with specific IgE and positive skin prick test results to A.s. were studied prospectively. Six of these had anaphylaxis (ANA) attributed to A.s. and 11 patients experienced concomitant chronic urticaria (CU). All patients were advised not to eat fish for 6 months. RESULTS: Four patients from the ANA group excluded fish, and ANA did not recur. Two other patients with ANA refused to exclude fish; one remained free of symptoms and the other experienced several urticarial episodes. During this 6-month period total IgE levels decreased in all six ANA patients; specific IgE for A.s. decreased in four patients and increased in two. Two patients from the CU group did not exclude fish, and symptoms persisted in these two patients. Clinical improvement was observed in 78% of the patients with CU who excluded fish. Total and specific IgE levels decreased in all the patients with CU. CONCLUSIONS: Because ANA symptoms are very severe, patients should always be advised to exclude fish until specific food allergens are identified. However, in patients with CU and specific IgE to A.s., only the clinical response to fish ingestion will determine the need for strict fish avoidance.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng
7001 a Matheu, Victoru Lund University,Lunds universitet,Neuroinflammation,Forskargrupper vid Lunds universitet,Lund University Research Groups4 aut0 (Swepub:lu)infl-vmu
7001 a Zubeldia, José Manuel4 aut
7001 a Rubio, Maria4 aut
7001 a Ordoqui, Elena4 aut
7001 a Lopez-Saez, Maria Pilar4 aut
7001 a Sierra, Zita4 aut
7001 a Tornero, Pilar4 aut
7001 a Baeza, Maria Luisa4 aut
7102 a Neuroinflammationb Forskargrupper vid Lunds universitet4 org
7730 t Annals of Allergy, Asthma & Immunologyg 86:6, s. 679-685q 86:6<679-685x 1081-1206
8564 8u https://lup.lub.lu.se/record/1119984

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