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Recommendations for the diagnosis and management of transthyretin amyloidosis with gastrointestinal manifestations

Nakov, Radislav (författare)
Department of Gastroenterology, Clinic of Gastroenterology, Tsaritsa Joanna University Hospital, Medical University of Sofia, Sofia, Bulgaria
Suhr, Ole B. (författare)
Umeå universitet,Avdelningen för medicin
Ianiro, Gianluca (författare)
Department of Gastroenterology, Digestive Disease Center, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University of Sacred Heart, Rome, Italy
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Kupcinskas, Juozas (författare)
Department of Gastroenterology and Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania
Segal, Jonathon P. (författare)
Department of Gastroenterology and Hepatology, St Mary's Hospital, London, United Kingdom
Dumitrascu, Dan L. (författare)
Second Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Heinrich, Henriette (författare)
Department of Gastroenterology and Hepatology, University Hospital Zürich, Zürich, Switzerland
Stojkovic-Lalosevic, Milica (författare)
Department of Gastroenterology and Hepatology, Clinical Centre of Serbia, Belgrade, Serbia
Barbov, Ivan (författare)
Department of Neurology, University Clinic for Neurology, Republic of North Macedonia, Skopje
Sarafov, Stayko (författare)
Department of Neurology, Expert Center for Hereditary Neurological and Metabolic Disorders, ATTR Amyloidosis Expert Center, Clinic of Nervous Diseases, Alexandrovska University Hospital, Medical University of Sofia
Tournev, Ivailo (författare)
Department of Neurology, Expert Center for Hereditary Neurological and Metabolic Disorders, ATTR Amyloidosis Expert Center, Clinic of Nervous Diseases, Alexandrovska University Hospital, Medical University of Sofia; Department of Cognitive Science and Psychology, New Bulgarian University, Sofia, Bulgaria
Nakov, Ventsislav (författare)
Department of Gastroenterology, Clinic of Gastroenterology, Tsaritsa Joanna University Hospital, Medical University of Sofia, Sofia, Bulgaria
Wixner, Jonas (författare)
Umeå universitet,Avdelningen för medicin
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 (creator_code:org_t)
Lippincott Williams & Wilkins, 2021
2021
Engelska.
Ingår i: European Journal of Gastroenterology and Hepathology. - : Lippincott Williams & Wilkins. - 0954-691X .- 1473-5687. ; 33:5, s. 613-622
Relaterad länk:
https://urn.kb.se/re...
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https://doi.org/10.1...
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  • Forskningsöversikt (refereegranskat)
Abstract Ämnesord
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  • Transthyretin amyloid (ATTR) amyloidosis is an adult-onset, rare systemic disorder characterized by the accumulation of misfolded fibrils in the body, including the peripheral nerves, the heart and the gastrointestinal tract. Gastrointestinal manifestations are common in hereditary (ATTRv) amyloidosis and are present even before the onset of the polyneuropathy in some cases. Delays in diagnosis of ATTRv amyloidosis with gastrointestinal manifestations commonly occur because of fragmented knowledge among gastroenterologists and general practitioners, as well as a shortage of centers of excellence and specialists dedicated to disease management. Although the disease is becoming well-recognized in the societies of Neurology and Cardiology, it is still unknown for most gastroenterologists. This review presents the recommendations for ATTRv amyloidosis with gastrointestinal manifestations elaborated by a working group of European gastroenterologists and neurologists, and aims to provide digestive health specialists with an overview of crucial aspects of ATTRv amyloidosis diagnosis to help facilitate rapid and accurate identification of the disease by focusing on disease presentation, misdiagnosis and management of gastrointestinal symptoms.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)

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