Presence of Aggregatibacter actinomycetemcomitans in young individuals: a 16-year clinical and microbiological follow-up study.

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Fältnamn	Indikatorer	Metadata
000		02745naa a2200313 4500
001		oai:DiVA.org:umu-31884
003		SwePub
008		100221s2009 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-318842 URI
024	7	a https://doi.org/10.1111/j.1600-051X.2009.01457.x2 DOI
040		a (SwePub)umu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Aberg, Carola Höglundu Umeå universitet,Institutionen för odontologi,Parodontologi4 aut0 (Swepub:umu)caha0028
245	1 0	a Presence of Aggregatibacter actinomycetemcomitans in young individuals :b a 16-year clinical and microbiological follow-up study.
264	1	c 2009
338		a print2 rdacarrier
520		a AIM: To look for clinical signs of periodontal disease in young adults who exhibited radiographic bone loss and detectable numbers of Aggregatibacter actinomycetemcomitans in their primary dentition. MATERIAL AND METHODS: Periodontal status and radiographic bone loss were examined in each of the subjects 16 years after the baseline observations. Techniques for anaerobic and selective culture, and checkerboard, were used to detect periodontitis-associated bacterial species. The isolated A. actinomycetemcomitans strains were characterized by polymerase chain reaction. RESULTS: Signs of localized attachment loss were found in three out of the 13 examined subjects. A. actinomycetemcomitans was recovered from six of these subjects and two of these samples were from sites with deepened probing depths and attachment loss. Among the isolated A. actinomycetemcomitans strains, serotypes a-c and e, but not d or f, were found. None of the isolated strains belonged to the highly leucotoxic JP2 clone, and one strain lacked genes for the cytolethal distending toxin. CONCLUSIONS: This study indicates that the presence of A. actinomycetemcomitans and early bone loss in the primary dentition does not necessarily predispose the individual to periodontal attachment loss in the permanent dentition.
700	1	a Sjödin, Bengt4 aut
700	1	a Lakio, Laura4 aut
700	1	a Pussinen, Pirkko J4 aut
700	1	a Johansson, Andersu Umeå universitet,Institutionen för odontologi,Parodontologi4 aut0 (Swepub:umu)anjo0002
700	1	a Claesson, Rolfu Umeå universitet,Institutionen för odontologi,Oral mikrobiologi4 aut0 (Swepub:umu)rolf0001
710	2	a Umeå universitetb Institutionen för odontologi4 org
773	0	t Journal of clinical periodontologyg 36:10, s. 815-22q 36:10<815-22x 1600-051X
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-31884
856	4 8	u https://doi.org/10.1111/j.1600-051X.2009.01457.x

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