WFRF:(Epperson Neill)
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LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03953naa a2200409 4500 | |
| 001 | oai:DiVA.org:uu-473459 | |
| 003 | SwePub | |
| 008 | 220427s2022 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4734592 URI |
| 024 | 7 | a https://doi.org/10.1038/s41598-022-07109-32 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Dubol, Manonu Uppsala universitet,Science for Life Laboratory, SciLifeLab,Comasco: Neuropsykofarmakologi4 aut0 (Swepub:uu)mandu832 |
| 245 | 1 0 | a Grey matter correlates of affective and somatic symptoms of premenstrual dysphoric disorder |
| 264 | c 2022-04-09 | |
| 264 | 1 | b Springer Nature,c 2022 |
| 338 | a electronic2 rdacarrier | |
| 500 | a Shared last authorship: Inger Sundström-Poromaa and Erika Comasco. | |
| 520 | a Ovarian hormones fluctuations across the menstrual cycle are experienced by about 58% of women in their fertile age. Maladaptive brain sensitivity to these changes likely leads to the severe psychological, cognitive, and physical symptoms repeatedly experienced by women with Premenstrual Dysphoric Disorder (PMDD) during the late luteal phase of the menstrual cycle. However, the neuroanatomical correlates of these symptoms are unknown. The relationship between grey matter structure and PMDD symptom severity was delineated using structural magnetic resonance imaging during the late luteal phase of fifty-one women diagnosed with PMDD, combined with Voxel- and Surface-Based Morphometry, as well as subcortical volumetric analyses. A negative correlation was found between depression-related symptoms and grey matter volume of the bilateral amygdala. Moreover, the severity of affective and somatic PMDD symptoms correlated with cortical thickness, gyrification, sulcal depth, and complexity metrics, particularly in the prefrontal, cingulate, and parahippocampal gyri. The present findings provide the first evidence of grey matter morphological characteristics associated with PMDD symptomatology in brain regions expressing ovarian hormone receptors and of relevance to cognitive-affective functions, thus potentially having important implications for understanding how structural brain characteristics relate to PMDD symptomatology. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng |
| 700 | 1 | a Wikström, Johan,d 1964-u Uppsala universitet,Radiologi4 aut0 (Swepub:uu)jwi06759 |
| 700 | 1 | a Lanzenberger, Rupertu Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria4 aut |
| 700 | 1 | a Epperson, C. Neillu Department of Psychiatry, Department of Family Medicine, University of Colorado School of Medicine-Anschutz Medical Campus, Aurora, USA4 aut |
| 700 | 1 | a Sundström Poromaa, Inger,d 1964-u Uppsala universitet,Reproduktiv hälsa4 aut0 (Swepub:uu)inspo702 |
| 700 | 1 | a Comasco, Erika,d 1982-u Uppsala universitet,Science for Life Laboratory, SciLifeLab,Comasco: Neuropsykofarmakologi4 aut0 (Swepub:uu)erico267 |
| 710 | 2 | a Uppsala universitetb Science for Life Laboratory, SciLifeLab4 org |
| 773 | 0 | t Scientific Reportsd : Springer Natureg 12:1q 12:1x 2045-2322 |
| 856 | 4 | u https://doi.org/10.1038/s41598-022-07109-3y Fulltext |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1654421/FULLTEXT02.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-473459 |
| 856 | 4 8 | u https://doi.org/10.1038/s41598-022-07109-3 |
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