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Periodontal disease...
Periodontal disease is associated with carotid plaque area: the Malmö Offspring Dental Study (MODS).
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- Jönsson, D. (författare)
- Malmö universitet,Malmö University,Swedish Public Dental Care of Skåne,Odontologiska fakulteten (OD),Swedish Dental Service of Skåne, Lund, Sweden
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- Orho-Melander, M. (författare)
- Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups,Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden,Kardiovaskulär forskning - hypertoni,Cardiovascular Research - Hypertension
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- Demmer, R. T. (författare)
- School of Public Health, University of Minnesota, Minneapolis, MN, United States; Mailman School of Public Health, Columbia University, New York, NY, United States,University of Minnesota
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- Engström, G. (författare)
- Lund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups,Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden
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- Melander, O. (författare)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,Skåne University Hospital
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- Klinge, Björn (författare)
- Karolinska Institutet,Malmö universitet,Malmö University,Karolinska Institute,Odontologiska fakulteten (OD),Division of Periodontology, Department of Dental Medicine, Karolinska Institutet, Solna, Sweden
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- Nilsson, P. M. (författare)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Department of Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden
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(creator_code:org_t)
- 2019-11-13
- 2020
- Engelska 9 s.
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Ingår i: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 287:3, s. 301-309
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Periodontal disease is associated with cardiovascular disease (CVD) but it is unknown if periodontal disease severity is associated with asymptomatic carotid plaque. The aim of the current population-based, observational study was to investigate if signs of periodontal disease are associated with the occurrence of carotid plaque and total plaque area (TPA). Methods: The Malmö Offspring Study (MOS) is a population-based study. MOS participants underwent a thorough cardiovascular phenotyping, including carotid ultrasonography. The Malmö Offspring Dental Study (MODS) invited participants of MOS for dental examination, including periodontal charting. Multivariable regression models were used to analyse the presence of carotid plaque and TPA in relation to periodontal parameters. Results: In all, 831 MODS participants were recruited, out of which 495 belonged to the children generation with mean age of 53 years, 63% had carotid plaque and 38% had moderate or severe periodontal disease. In models adjusted for CVD risk factors, the OR for having carotid plaque in subjects with vs without periodontal disease was 1.75 (95% CI: 1.11–2.78). In a linear model with TPA as dependent and number of periodontal pockets ≥ 4 mm as independent variable, the adjusted beta-coefficient was 0.34 mm2 (95% CI 0.16–0.52). Conclusion: Individuals within the highest quartile of periodontal pockets are expected to have 9 mm2 larger TPA compared to those without pockets. Our results suggest that intervention studies addressing periodontal disease could be useful for prevention of CVD.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- atherosclerosis
- carotid plaque
- epidemiology
- periodontal disease
- atherosclerosis
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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