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The use of Methadon...
The use of Methadone in adult patients with cancer-pain at a governmental cancer centre in India
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- Palat, Gayatri (författare)
- MNJ Institute of Oncology and Regional Cancer Center
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- Algotsson, Charlotte (författare)
- Lund University,Lunds universitet,Geriatrik,Forskargrupper vid Lunds universitet,Geriatrics,Lund University Research Groups
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- Rayala, Spandana (författare)
- MNJ Institute of Oncology and Regional Cancer Center
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Haridass, Vikranth (författare)
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- Nethagani, Jaya (författare)
- MNJ Institute of Oncology and Regional Cancer Center
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- Mustafa, Ahmed (författare)
- MNJ Institute of Oncology and Regional Cancer Center
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- Rapelli, Vineela (författare)
- MNJ Institute of Oncology and Regional Cancer Center
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- Gebre-Medhin, Maria (författare)
- Lund University,Lunds universitet,Huvud- och halscancergruppen,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Systemisk strålterapi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Head and Neck Cancer Research Group,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Systemic radiation therapy,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
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- Brun, Eva (författare)
- Lund University,Lunds universitet,Huvud- och halscancergruppen,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Systemisk strålterapi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Head and Neck Cancer Research Group,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Systemic radiation therapy,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
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- Segerlantz, Mikael (författare)
- Lund University,Lunds universitet,Palliativt Utvecklingscentrum,Forskargrupper vid Lunds universitet,Palliativ vård,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,The Institute for Palliative Care,Lund University Research Groups,Palliative care,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Region Skåne, Primary health care
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(creator_code:org_t)
- 2021
- 2021
- Engelska.
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Ingår i: Indian Journal of Palliative Care. - 0973-1075. ; 27:1, s. 139-145
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.4...
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Abstract
Ämnesord
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- Background: Management of cancer-related pain relies on the access to opioids. When regular opioids as morphine are not tolerated or are insufficient, adjuvant opioids as methadone are an affordable and effective analgesic. Aim: The aim of the project was to describe the pattern of use and clinical experiences of methadone in patients with cancer-related pain at a low-resource hospital in Hyderabad, one of few Indian cancer centers with permission to prescribe methadone. Methods: Medical records of all patients who had been prescribed methadone, September 9, 2017 and November 19, 2019 were studied retrospectively. Data on analgesic treatment and opioid side effects were analyzed. Results: A total of 93 adult cancer patients were included in the study. A majority of patients (79%) were prescribed opioid analgesic, mainly morphine, before methadone introduction. The initial daily dose of methadone ranged between 5 and 22.5 years and in the vast majority of the patients 5 mg, divided in two daily administrations. A good analgesic effect, with decreased pain, was reported in 60% of the patients. No severe side effects were reported. Conclusions: In this study, methadone as a primary opioid was used with a good analgesic effect for cancer pain in a low-resource setting. Indication for methadone was mainly uncontrolled pain with a regular opioid treatment. No severe adverse effects were reported. Further research and prospective studies are needed on methadone treatment in low-resource settings to establish the robust guidelines to support prescribing physicians.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- methadone
- Cancer-pain
- India
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Palat, Gayatri
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Algotsson, Charl ...
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Rayala, Spandana
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Haridass, Vikran ...
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Nethagani, Jaya
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Mustafa, Ahmed
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visa fler...
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Rapelli, Vineela
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Gebre-Medhin, Ma ...
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Brun, Eva
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Segerlantz, Mika ...
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Indian Journal o ...
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Lunds universitet