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WFRF:(Schutzer Steven E.)
 

Sökning: WFRF:(Schutzer Steven E.) > Myalgic encephalomy...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004310naa a2200505 4500
001oai:DiVA.org:uu-514918
003SwePub
008231027s2023 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5149182 URI
0247 a https://doi.org/10.1080/07853890.2023.22083722 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Schutzer, Steven E.u Rutgers NJ Med Sch, Dept Med, Newark, NJ USA.;Rutgers New Jersey Med Sch, 185 South Orange Ave, Newark, NJ 07103 USA.4 aut
2451 0a Myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia are indistinguishable by their cerebrospinal fluid proteomes
264 1b Taylor & Francis,c 2023
338 a electronic2 rdacarrier
520 a Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and fibromyalgia have overlapping neurologic symptoms particularly disabling fatigue. This has given rise to the question whether they are distinct central nervous system (CNS) entities or is one an extension of the other.Material and methods: To investigate this, we used unbiased quantitative mass spectrometry-based proteomics to examine the most proximal fluid to the brain, cerebrospinal fluid (CSF). This was to ascertain if the proteome profile of one was the same or different from the other. We examined two separate groups of ME/CFS, one with (n = 15) and one without (n = 15) fibromyalgia.Results: We quantified a total of 2083 proteins using immunoaffinity depletion, tandem mass tag isobaric labelling and offline two-dimensional liquid chromatography coupled to tandem mass spectrometry, including 1789 that were quantified in all the CSF samples. ANOVA analysis did not yield any proteins with an adjusted p value <.05.Conclusion: This supports the notion that ME/CFS and fibromyalgia as currently defined are not distinct entities.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng
653 a Chronic fatigue syndrome
653 a proteomics
653 a cerebrospinal fluid
653 a fibromyalgia
7001 a Liu, Taou Pacific Northwest Natl Lab, Integrat Omics, Biol Sci, Richland, WA USA.4 aut
7001 a Tsai, Chia-Fengu Pacific Northwest Natl Lab, Integrat Omics, Biol Sci, Richland, WA USA.4 aut
7001 a Petyuk, Vladislav A.u Pacific Northwest Natl Lab, Integrat Omics, Biol Sci, Richland, WA USA.4 aut
7001 a Schepmoes, Athena A.u Pacific Northwest Natl Lab, Integrat Omics, Biol Sci, Richland, WA USA.4 aut
7001 a Wang, Yi-Tingu Uppsala universitet,Analytisk kemi4 aut
7001 a Weitz, Karl K.u Pacific Northwest Natl Lab, Integrat Omics, Biol Sci, Richland, WA USA.4 aut
7001 a Bergquist, Jonasu Uppsala universitet,Analytisk kemi4 aut0 (Swepub:uu)jbe25356
7001 a Smith, Richard D.u Pacific Northwest Natl Lab, Integrat Omics, Biol Sci, Richland, WA USA.4 aut
7001 a Natelson, Benjamin H.u Icahn Sch Med Mt Sinai, Dept Neurol, New York, NY USA.4 aut
7102 a Rutgers NJ Med Sch, Dept Med, Newark, NJ USA.;Rutgers New Jersey Med Sch, 185 South Orange Ave, Newark, NJ 07103 USA.b Pacific Northwest Natl Lab, Integrat Omics, Biol Sci, Richland, WA USA.4 org
7730 t Annals of Medicined : Taylor & Francisg 55:1q 55:1x 0785-3890x 1365-2060
8564 u https://doi.org/10.1080/07853890.2023.2208372y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1807731/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-514918
8564 8u https://doi.org/10.1080/07853890.2023.2208372

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