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Recent advances in the modification of carbon-based quantum dots for biomedical applications

Alaghmandfard, A. (author)
Sedighi, O. (author)
Tabatabaei Rezaei, N. (author)
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Abedini, A. A. (author)
Malek Khachatourian, A. (author)
Toprak, Muhammet, 1973- (author)
KTH,Tillämpad fysik
Seifalian, A. (author)
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 (creator_code:org_t)
Elsevier BV, 2021
2021
English.
In: Materials science & engineering. C, biomimetic materials, sensors and systems. - : Elsevier BV. - 0928-4931 .- 1873-0191. ; 120
  • Research review (peer-reviewed)
Abstract Subject headings
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  • Carbon-based quantum dots (CDs) are mainly divided into two sub-groups; carbon quantum dots (CQDs) and graphene quantum dots (GQDs), which exhibit outstanding photoluminescence (PL) properties, low toxicity, superior biocompatibility and facile functionalization. Regarding these features, they have been promising candidates for biomedical science and engineering applications. In this work, we reviewed the efforts made to modify these zero-dimensional nano-materials to obtain the best properties for bio-imaging, drug and gene delivery, cancer therapy, and bio-sensor applications. Five main surface modification techniques with outstanding results are investigated, including doping, surface functionalization, polymer capping, nano-composite and core-shell structures, and the drawbacks and challenges in each of these methods are discussed.

Subject headings

NATURVETENSKAP  -- Kemi -- Materialkemi (hsv//swe)
NATURAL SCIENCES  -- Chemical Sciences -- Materials Chemistry (hsv//eng)

Keyword

Biomedical application
Carbon-based quantum dots
Surface modification
Biocompatibility
Carbon
Carbon Quantum Dots
Composite structures
Gene transfer
Graphene quantum dots
Medical applications
Nanocomposites
Nanocrystals
Nanosensors
Biomedical applications
Biomedical science
Core shell structure
Functionalizations
Photoluminescence properties
Surface Functionalization
Surface modification techniques
Zero-dimensional
Semiconductor quantum dots

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