Diet and alcohol as risk factors for rheumatoid arthritis: a nested case-control study

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Sundström, BjörnUmeå universitet,Reumatologi (författare)

Diet and alcohol as risk factors for rheumatoid arthritis : a nested case-control study

Artikel/kapitelEngelska2015

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2014-11-27
Springer Science and Business Media LLC,2015
printrdacarrier

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LIBRIS-ID:oai:DiVA.org:umu-101388
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-101388URI
https://doi.org/10.1007/s00296-014-3185-xDOI

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Språk:engelska
Sammanfattning på:engelska

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Ämneskategori:art swepub-publicationtype

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The aim of this study was to investigate whether alcohol and diet, assessed as both macronutrients and dietary patterns, increased the risk of development of rheumatoid arthritis (RA) through a nested case-control design in the Vasterbotten Intervention Program (VIP) cohort. Individuals in the VIP who had developed RA after the dietary survey were identified from medical records at the department of rheumatology at the University Hospital, UmeAyen (n = 386), and matched to 1,886 controls from the same database. Diet was assessed as food groups, as macronutrients and as scores of dietary patterns, namely the carbohydrate-restricted diet score, the Mediterranean diet score and the healthy diet indicator score. When analysing the dietary patterns, consumption of food groups and different macronutrients, a significant association was found in the highest tertile of carbohydrate-restricted diet among the cases with a subsequent anti-CCP-positive disease 1.40 (1.02-1.92), as well as in the highest tertile of protein consumption among smokers (OR = 1.80, 95 % CI 1.09-2.95). However, after additional adjustment for sodium intake, these associations were no longer statistically significant. No association was observed between alcohol consumption and the risk of RA. To summarize, there were no significant associations between diet, or alcohol consumption, and the risk of development of RA within this cohort. The lack of any significant associations of alcohol consumption may be explained by a low consumption in the studied population overall or alternatively by methodological issues raised recently.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Reumatologi och inflammation hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Rheumatology and Autoimmunity hsv//eng
Rheumatoid arthritis
Epidemiology
Alcohol
Diet

Biuppslag (personer, institutioner, konferenser, titlar ...)

Johansson, IngegerdUmeå universitet,Institutionen för odontologi(Swepub:umu)injo0003 (författare)
Rantapää-Dahlqvist, SolbrittUmeå universitet,Reumatologi(Swepub:umu)sora0001 (författare)
Umeå universitetReumatologi (creator_code:org_t)

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Ingår i:Rheumatology International: Springer Science and Business Media LLC35:3, s. 533-5390172-81721437-160X

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Av författaren/redakt...: Sundström, Björn; Johansson, Ingeg ...; Rantapää-Dahlqvi ...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Reumatologi och ...

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Av lärosätet: Umeå universitet

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