Sökning: WFRF:(Ferri E) > Genetically Determi...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 13737naa a2201393 4500 | |
001 | oai:DiVA.org:uu-407653 | |
003 | SwePub | |
008 | 200330s2020 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:143029246 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4076532 URI |
024 | 7 | a https://doi.org/10.3389/fonc.2019.015392 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1430292462 URI |
040 | a (SwePub)uud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Moore, Amyu NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 aut |
245 | 1 0 | a Genetically Determined Height and Risk of Non-hodgkin Lymphoma |
264 | c 2020-01-28 | |
264 | 1 | b FRONTIERS MEDIA SA,c 2020 |
338 | a electronic2 rdacarrier | |
520 | a Although the evidence is not consistent, epidemiologic studies have suggested that taller adult height may be associated with an increased risk of some non-Hodgkin lymphoma (NHL) subtypes. Height is largely determined by genetic factors, but how these genetic factors may contribute to NHL risk is unknown. We investigated the relationship between genetic determinants of height and NHL risk using data from eight genome-wide association studies (GWAS) comprising 10,629 NHL cases, including 3,857 diffuse large B-cell lymphoma (DLBCL), 2,847 follicular lymphoma (FL), 3,100 chronic lymphocytic leukemia (CLL), and 825 marginal zone lymphoma (MZL) cases, and 9,505 controls of European ancestry. We evaluated genetically predicted height by constructing polygenic risk scores using 833 height-associated SNPs. We used logistic regression to estimate odds ratios (OR) and 95% confidence intervals (CI) for association between genetically determined height and the risk of four NHL subtypes in each GWAS and then used fixed-effect meta-analysis to combine subtype results across studies. We found suggestive evidence between taller genetically determined height and increased CLL risk (OR = 1.08, 95% CI = 1.00-1.17, p = 0.049), which was slightly stronger among women (OR = 1.15, 95% CI: 1.01-1.31, p = 0.036). No significant associations were observed with DLBCL, FL, or MZL. Our findings suggest that there may be some shared genetic factors between CLL and height, but other endogenous or environmental factors may underlie reported epidemiologic height associations with other subtypes. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
653 | a non-Hodgkin lymphoma | |
653 | a height | |
653 | a genetics | |
653 | a chronic lymphocytic leukemia | |
653 | a diffuse large B-cell lymphoma | |
653 | a follicular lymphoma | |
653 | a marginal zone lymphoma | |
653 | a polygenic risk score | |
700 | 1 | a Kane, Eleanoru Karolinska Institutet4 aut |
700 | 1 | a Wang, Zhaomingu St Jude Childrens Res Hosp, Dept Computat Biol, 332 N Lauderdale St, Memphis, TN 38105 USA;NCI, Lab Translat Genom, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Panagiotou, Orestis A.u Brown Univ, Sch Publ Hlth, Dept Hlth Serv Policy & Practice, Providence, RI 02912 USA;Brown Univ, Sch Publ Hlth, Ctr Gerontol & Healthcare Res, Providence, RI 02912 USA4 aut |
700 | 1 | a Teras, Lauren R.u Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA4 aut |
700 | 1 | a Monnereau, Alainu INSERM, Epidemiol Childhood & Adolescent Canc Grp, Ctr Res Epidemiol & Stat Sorbonne Paris Cite CRES, Paris, France;Univ Paris 05, Paris, France;Inst Bergonie, Registre Hemopathies Malignes Gironde, Bordeaux, France4 aut |
700 | 1 | a Wong Doo, Nicoleu Canc Council Victoria, Canc Epidemiol & Intelligence Div, Melbourne, Vic, Australia4 aut |
700 | 1 | a Machiela, Mitchell J.u NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Skibola, Christine F.u Emory Univ, Sch Med, Dept Hematol & Med Oncol, Atlanta, GA USA4 aut |
700 | 1 | a Slager, Susan L.u Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA4 aut |
700 | 1 | a Salles, Gillesu Hosp Civils Lyon, Dept Hematol, Lyon, France;Univ Lyon 1, Dept Hematol, Lyon, France;Inst Natl Sante & Rech Med UMR1052 Pierre Benite, Canc Res Ctr Lyon, Equipe Expt & Clin Models Lymphomagenesis, Lyon, France4 aut |
700 | 1 | a Camp, Nicola J.u Univ Utah, Sch Med, Dept Internal Med, Div Hematol & Hematol Malignancies, Salt Lake City, UT USA;Univ Utah, Sch Med, Huntsman Canc Inst, Salt Lake City, UT USA4 aut |
700 | 1 | a Bracci, Paige M.u Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA USA4 aut |
700 | 1 | a Nieters, Alexandrau Univ Med Ctr Freiburg, Ctr Chron Immunodeficiency, Freiburg, Germany4 aut |
700 | 1 | a Vermeulen, Roel C. H.u Univ Utrecht, Inst Risk Assessment Sci, Div Environm Epidemiol, Utrecht, Netherlands;Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands4 aut |
700 | 1 | a Vijai, Josephu Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, 1275 York Ave, New York, NY 10021 USA4 aut |
700 | 1 | a Smedby, Karin E.u Karolinska Inst, Dept Med, Solna, Solna, Sweden;Karolinska Univ Hosp, Hematol Ctr, Stockholm, Sweden4 aut |
700 | 1 | a Zhang, Yaweiu Yale Sch Publ Hlth, Dept Environm Hlth Sci, New Haven, CT USA4 aut |
700 | 1 | a Vajdic, Claire M.u Univ New South Wales, Ctr Big Data Res Hlth, Sydney, NSW, Australia4 aut |
700 | 1 | a Cozen, Wendyu Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA 90007 USA;Univ Southern Calif, Keck Sch Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90007 USA4 aut |
700 | 1 | a Spinelli, John J.u BC Canc, Canc Control Res, Vancouver, BC, Canada;Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada4 aut |
700 | 1 | a Hjalgrim, Henriku Karolinska Institutet4 aut |
700 | 1 | a Giles, Graham G.u Canc Council Victoria, Canc Epidemiol & Intelligence Div, Melbourne, Vic, Australia;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic, Australia4 aut |
700 | 1 | a Link, Brian K.u Univ Iowa, Carver Coll Med, Dept Internal Med, Iowa City, IA USA4 aut |
700 | 1 | a Clavel, Jacquelineu INSERM, Epidemiol Childhood & Adolescent Canc Grp, Ctr Res Epidemiol & Stat Sorbonne Paris Cite CRES, Paris, France;Univ Paris 05, Paris, France4 aut |
700 | 1 | a Arslan, Alan A.u NYU, Sch Med, Dept Obstet & Gynecol, New York, NY USA;NYU, Sch Med, Dept Environm Med, New York, NY USA;NYU, Langone Med Ctr, Perlmutter Canc Ctr, New York, NY USA4 aut |
700 | 1 | a Purdue, Mark P.u Ontario Hlth Study, Toronto, ON, Canada4 aut |
700 | 1 | a Tinker, Lesley F.u Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1124 Columbia St, Seattle, WA 98104 USA4 aut |
700 | 1 | a Albanes, Demetriusu NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Ferri, Giovanni M.u Univ Bari, Interdisciplinary Dept Med, Bari, Italy4 aut |
700 | 1 | a Habermann, Thomas M.u Mayo Clin, Coll Med & Sci, Div Gen Internal Med, Rochester, MN USA4 aut |
700 | 1 | a Adami, Hans-Olovu Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden;Harvard Sch Publ Hlth, Dept Epidmiol, Boston, MA USA4 aut |
700 | 1 | a Becker, Nikolausu German Canc Res Ctr, Div Canc Epidmiol, Heidelberg, Germany4 aut |
700 | 1 | a Benavente, Yolandau Catalan Inst OncologyIDIBELL, Canc Epidemiol Res Programme, Barcelona, Spain;CIBER Epidemiol & Salud Publ, Barcelona, Spain4 aut |
700 | 1 | a Bisanzi, Simonettau Prevent & Res Inst ISPRO, Oncol Network, Reg Canc Prevent Lab, Florence, Italy4 aut |
700 | 1 | a Boffetta, Paolou Icahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 USA4 aut |
700 | 1 | a Brennan, Paulu IARC, Lyon, France4 aut |
700 | 1 | a Brooks-Wilson, Angela R.u BC Canc, Genome Sci Ctr, Vancouver, BC, Canada;Simon Fraser Univ, Dept Biomed Physiol & Kinesiol, Burnaby, BC, Canada4 aut |
700 | 1 | a Canzian, Federicou German Canc Res Ctr, Genom Epidemiol Grp, Heidelberg, Germany4 aut |
700 | 1 | a Conde, Luciau UCL, Inst Canc, Bill Lyons Informat Ctr, London, England4 aut |
700 | 1 | a Cox, David G.u Ctr Leon Berard, Canc Res Ctr Lyon, INSERM, U1052, Lyon, France4 aut |
700 | 1 | a Curtin, Karenu Univ Utah, Sch Med, Dept Internal Med, Salt Lake City, UT USA4 aut |
700 | 1 | a Foretova, Lenkau Masaryk Mem Canc Inst & MF MU, Dept Canc Epidemiol & Genet, Brno, Czech Republic4 aut |
700 | 1 | a Gapstur, Susan M.u Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA4 aut |
700 | 1 | a Ghesquieres, Herveu Inst Natl Sante & Rech Med UMR1052 Pierre Benite, Canc Res Ctr Lyon, Equipe Expt & Clin Models Lymphomagenesis, Lyon, France;Ctr Leon Berard, Dept Hematol, Lyon, France4 aut |
700 | 1 | a Glenn, Marthau Huntsman Canc Inst, Dept Internal Med, Salt Lake City, UT USA4 aut |
700 | 1 | a Glimelius, Bengtu Uppsala universitet,Experimentell och klinisk onkologi4 aut0 (Swepub:uu)bengglim |
700 | 1 | a Jackson, Rebecca D.u Ohio State Univ, Div Endocrinol Diabet & Metab, Columbus, OH USA4 aut |
700 | 1 | a Lan, Qingu NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Liebow, Marku Mayo Clin, Coll Med & Sci, Div Gen Internal Med, Rochester, MN USA4 aut |
700 | 1 | a Maynadie, Marcu Univ Burgundy, Registre Hemopathies Malignes Cote dOr, INSERM, U1231, Dijon, France;Dijon Univ Hosp, Dijon, France4 aut |
700 | 1 | a McKay, Jamesu IARC, Lyon, France4 aut |
700 | 1 | a Melbye, Madsu Statens Serum Inst, Dept Epidemiol Res, Div Hlth Surveillance & Res, Copenhagen, Denmark;Stanford Univ, Dept Med, Sch Med, Stanford, CA 94305 USA4 aut |
700 | 1 | a Miligi, Luciau Prevent & Res Inst ISPRO, Oncol Network, Environm & Occupat Epidemiol Unit, Florence, Italy4 aut |
700 | 1 | a Milne, Roger L.u Canc Council Victoria, Canc Epidemiol & Intelligence Div, Melbourne, Vic, Australia;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Melbourne, Vic, Australia4 aut |
700 | 1 | a Molina, Thierry J.u Univ Paris 05, Sorbonne Paris Cite, Necker Enfants Malades, Dept Pathol,AP HP, Paris, France4 aut |
700 | 1 | a Morton, Lindsay M.u NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 aut |
700 | 1 | a North, Kari E.u Univ N Carolina, Dept Epidemiol, Chapel Hill, NC 27515 USA;Univ N Carolina, Carolina Ctr Genome Sci, Chapel Hill, NC 27515 USA4 aut |
700 | 1 | a Offit, Kennethu Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, 1275 York Ave, New York, NY 10021 USA4 aut |
700 | 1 | a Padoan, Marinau Univ Piemonte Orientale, Dept Translat Med, CPO Piemonte, Novara, Italy;Univ Piemonte Orientale, Dept Translat Med, Unit Med Stat & Epidemiol, Novara, Italy4 aut |
700 | 1 | a Patel, Alpa V.u Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA4 aut |
700 | 1 | a Piro, Sarau Prevent & Res Inst ISPRO, Oncol Network, Environm & Occupat Epidemiol Unit, Florence, Italy4 aut |
700 | 1 | a Ravichandran, Vigneshu Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, 1275 York Ave, New York, NY 10021 USA4 aut |
700 | 1 | a Riboli, Eliou Imperial Coll London, Sch Publ Hlth, London, England4 aut |
700 | 1 | a de Sanjose, Silviau Catalan Inst OncologyIDIBELL, Canc Epidemiol Res Programme, Barcelona, Spain;CIBER Epidemiol & Salud Publ, Barcelona, Spain4 aut |
700 | 1 | a Severson, Richard K.u Wayne State Univ, Dept Family Med & Publ Hlth Sci, Detroit, MI USA4 aut |
700 | 1 | a Southey, Melissa C.u Univ Melbourne, Dept Pathol, Genet Epidmiol Lab, Melbourne, Vic, Australia4 aut |
700 | 1 | a Staines, Anthonyu Dublin City Univ, Sch Nursing & Human Sci, Dublin, Ireland4 aut |
700 | 1 | a Stewart, Carolynu Mem Sloan Kettering Canc Ctr, Dept Med, Clin Genet Serv, 1275 York Ave, New York, NY 10021 USA4 aut |
700 | 1 | a Travis, Ruth C.u Univ Oxford, Canc Epidmiol Unit, Oxford, England4 aut |
700 | 1 | a Weiderpass, Elisabeteu World Hlth Org, Int Agcy Res Canc, Lyon, France4 aut |
700 | 1 | a Weinstein, Stephanieu NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Zheng, Tongzhangu Brown Sch Publ Hlth, Dept Epidmiol, Providence, RI USA4 aut |
700 | 1 | a Chanock, Stephen J.u NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Chatterjee, Nilanjanu NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA;Johns Hopkins Univ, Dept Biostat, Bloomberg Sch Publ Hlth, Baltimore, MD 21205 USA;Johns Hopkins Univ, Sch Med, Dept Oncol, Baltimore, MD 21205 USA4 aut |
700 | 1 | a Rothman, Nathanielu NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Birmann, Brenda M.u Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA;Harvard Med Sch, Boston, MA 02115 USA4 aut |
700 | 1 | a Cerhan, James R.u Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA4 aut |
700 | 1 | a Berndt, Sonja I.u NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 aut |
710 | 2 | a Karolinska Institutetb NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA4 org |
773 | 0 | t Frontiers in Oncologyd : FRONTIERS MEDIA SAg 9q 9x 2234-943X |
856 | 4 | u https://doi.org/10.3389/fonc.2019.01539y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1417768/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://doi.org/10.3389/fonc.2019.01539 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-407653 |
856 | 4 8 | u https://doi.org/10.3389/fonc.2019.01539 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:143029246 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.