Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

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Fältnamn	Indikatorer	Metadata
000		10650naa a2202065 4500
001		oai:DiVA.org:umu-166521
003		SwePub
008		191217s2019 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:139843429
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1665212 URI
024	7	a https://doi.org/10.1016/S1474-4422(18)30403-42 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1398434292 URI
040		a (SwePub)umud (SwePub)ki
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Nichols, Emma4 aut
245	1 0	a Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016 :b a systematic analysis for the Global Burden of Disease Study 2016
264	1	b Elsevier,c 2019
338		a electronic2 rdacarrier
520		a Background: The number of individuals living with dementia is increasing, negatively affecting families, communities, and health-care systems around the world. A successful response to these challenges requires an accurate understanding of the dementia disease burden. We aimed to present the first detailed analysis of the global prevalence, mortality, and overall burden of dementia as captured by the Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2016, and highlight the most important messages for clinicians and neurologists.Methods: GBD 2016 obtained data on dementia from vital registration systems, published scientific literature and surveys, and data from health-service encounters on deaths, excess mortality, prevalence, and incidence from 195 countries and territories from 1990 to 2016, through systematic review and additional data-seeking efforts. To correct for differences in cause of death coding across time and locations, we modelled mortality due to dementia using prevalence data and estimates of excess mortality derived from countries that were most likely to code deaths to dementia relative to prevalence. Data were analysed by standardised methods to estimate deaths, prevalence, years of life lost (YLLs), years of life lived with disability (YLDs), and disability-adjusted life-years (DALYs; computed as the sum of YLLs and YLDs), and the fractions of these metrics that were attributable to four risk factors that met GBD criteria for assessment (high body-mass index [BMI], high fasting plasma glucose, smoking, and a diet high in sugarsweetened beverages).Findings: In 2016, the global number of individuals who lived with dementia was 43.8 million (95% uncertainty interval [UI] 3 7. 8-51.0), increased from 20.2 million (17. 4-23 5) in 1990. This increase of 117% (95% UI 114-121) contrasted with a minor increase in age-standardised prevalence of 1.7% (1.0-2.4), from 701 cases (95% UI 602-815) per 100 000 population in 1990 to 712 cases (614-828) per 100 000 population in 2016. More women than men had dementia in 2016 (27.0 million, 95% UI 23 .3-31. 4, vs 16.8 million, 14.4-19.6), and dementia was the fifth leading cause of death globally, accounting for 2.4 million (95% UI 2.1-2.8) deaths. Overall, 28.8 million (95% UI 24. 5-34. 0) DALYs were attributed to dementia; 6.4 million (95% UI 3 .4-10. 5) of these could be attributed to the modifiable GBD risk factors of high BMI, high fasting plasma glucose, smoking, and a high intake of sugar-sweetened beverages.Interpretation: The global number of people living with dementia more than doubled from 1990 to 2016, mainly due to increases in population ageing and growth. Although differences in coding for causes of death and the heterogeneity in case-ascertainment methods constitute major challenges to the estimation of the burden of dementia, future analyses should improve on the methods for the correction of these biases. Until breakthroughs are made in prevention or curative treatment, dementia will constitute an increasing challenge to health-care systems worldwide.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
700	1	a Szoeke, Cassandra E. I.4 aut
700	1	a Vollset, Stein Emil4 aut
700	1	a Abbasi, Nooshin4 aut
700	1	a Abd-Allah, Foad4 aut
700	1	a Abdela, Jemal4 aut
700	1	a Aichour, Miloud Taki Eddine4 aut
700	1	a Akinyemi, Rufus O.4 aut
700	1	a Alahdab, Fares4 aut
700	1	a Asgedom, Solomon W.4 aut
700	1	a Awasthi, Ashish4 aut
700	1	a Barker-Collo, Suzanne L.4 aut
700	1	a Baune, Bernhard T.4 aut
700	1	a Bejot, Yannick4 aut
700	1	a Belachew, Abate B.4 aut
700	1	a Bennett, Derrick A.4 aut
700	1	a Bijani, Belete Biadgo Ali4 aut
700	1	a Bin Sayeed, Muhammad Shahdaat4 aut
700	1	a Brayne, Carol4 aut
700	1	a Carpenter, David O.4 aut
700	1	a Carvalho, Felix4 aut
700	1	a Catala-Lopez, Ferran4 aut
700	1	a Cerin, Ester4 aut
700	1	a Choi, Jee-Young J.4 aut
700	1	a Dang, Ahn K.4 aut
700	1	a Degefa, Meaza G.4 aut
700	1	a Djalalinia, Shirin4 aut
700	1	a Dubey, Manisha4 aut
700	1	a Duken, Eyasu Ejeta4 aut
700	1	a Edvardsson, Davidu Umeå universitet,Institutionen för omvårdnad,School of Nursing and Midwifery, La Trobe University, Melbourne, VIC, Australia4 aut0 (Swepub:umu)dadlut99
700	1	a Endres, Matthias4 aut
700	1	a Eskandarieh, Sharareh4 aut
700	1	a Faro, Andre4 aut
700	1	a Farzadfar, Farshad4 aut
700	1	a Fereshtehnejad, Seyed-Mohammadu Karolinska Institutet4 aut
700	1	a Fernandes, Eduarda4 aut
700	1	a Filip, Irina4 aut
700	1	a Fischer, Florian4 aut
700	1	a Gebre, Abadi K.4 aut
700	1	a Geremew, Demeke4 aut
700	1	a Ghasemi-Kasman, Maryam4 aut
700	1	a Gnedovskaya, Elena V.4 aut
700	1	a Gupta, Rajeev4 aut
700	1	a Hachinski, Vladimir4 aut
700	1	a Hagos, Tekleberhan B.4 aut
700	1	a Hamidi, Samer4 aut
700	1	a Hankey, Graeme J.4 aut
700	1	a Haro, Josep M.4 aut
700	1	a Hay, Simon I.4 aut
700	1	a Irvani, Seyed Sina N.4 aut
700	1	a Jha, Ravi P.4 aut
700	1	a Jonas, Jost B.4 aut
700	1	a Kalani, Rizwan4 aut
700	1	a Karch, Andre4 aut
700	1	a Kasaeian, Amir4 aut
700	1	a Khader, Yousef Saleh4 aut
700	1	a Khalil, Ibrahim A.4 aut
700	1	a Khan, Ejaz Ahmad4 aut
700	1	a Khanna, Tripti4 aut
700	1	a Khoja, Tawfik A. M.4 aut
700	1	a Khubchandani, Jagdish4 aut
700	1	a Kisa, Adnan4 aut
700	1	a Kissimova-Skarbek, Katarzyna4 aut
700	1	a Kivimaki, Mika4 aut
700	1	a Koyanagi, Ai4 aut
700	1	a Krohn, Kristopher J.4 aut
700	1	a Logroscino, Giancarlo4 aut
700	1	a Lorkowski, Stefan4 aut
700	1	a Majdan, Marek4 aut
700	1	a Malekzadeh, Reza4 aut
700	1	a Marz, Winfried4 aut
700	1	a Massano, Joao4 aut
700	1	a Mengistu, Getnet4 aut
700	1	a Meretoja, Atte4 aut
700	1	a Mohammadi, Moslem4 aut
700	1	a Mohammadi-Khanaposhtani, Maryam4 aut
700	1	a Mokdad, Ali H.4 aut
700	1	a Mondello, Stefania4 aut
700	1	a Moradi, Ghobad4 aut
700	1	a Nagel, Gabriele4 aut
700	1	a Naghavi, Mohsen4 aut
700	1	a Naik, Gurudatta4 aut
700	1	a Nguyen, Long H.4 aut
700	1	a Nguyen, Trang H.4 aut
700	1	a Nirayo, Yirga L.4 aut
700	1	a Nixon, Molly R.4 aut
700	1	a Ofori-Asenso, Richard4 aut
700	1	a Ogbo, Felix A.4 aut
700	1	a Olagunju, Andrew T.4 aut
700	1	a Owolabi, Mayowa O.4 aut
700	1	a Panda-Jonas, Songhomitra4 aut
700	1	a Passos, Valeria M. de Azeredo4 aut
700	1	a Pereira, David M.4 aut
700	1	a Pinilla-Monsalve, Gabriel D.4 aut
700	1	a Piradov, Michael A.4 aut
700	1	a Pond, Constance D.4 aut
700	1	a Poustchi, Hossein4 aut
700	1	a Qorbani, Mostafa4 aut
700	1	a Radfar, Amir4 aut
700	1	a Reiner, Robert C.4 aut
700	1	a Robinson, Stephen R.4 aut
700	1	a Roshandel, Gholamreza4 aut
700	1	a Rostami, Ali4 aut
700	1	a Russ, Tom C.4 aut
700	1	a Sachdev, Perminder S.4 aut
700	1	a Safari, Hosein4 aut
700	1	a Safiri, Saeid4 aut
700	1	a Sahathevan, Ramesh4 aut
700	1	a Salimi, Yahya4 aut
700	1	a Satpathy, Maheswar4 aut
700	1	a Sawhney, Monika4 aut
700	1	a Saylan, Mete4 aut
700	1	a Sepanlou, Sadaf G.4 aut
700	1	a Shafieesabet, Azadeh4 aut
700	1	a Shaikh, Masood A.4 aut
700	1	a Sahraian, Mohammad A.4 aut
700	1	a Shigematsu, Mika4 aut
700	1	a Shiri, Rahman4 aut
700	1	a Shiue, Ivy4 aut
700	1	a Silva, Joao P.4 aut
700	1	a Smith, Mari4 aut
700	1	a Sobhani, Soheila4 aut
700	1	a Stein, Dan J.4 aut
700	1	a Tabares-Seisdedos, Rafael4 aut
700	1	a Tovani-Palone, Marcos R.4 aut
700	1	a Tran, Bach X.4 aut
700	1	a Tran, Tung T.4 aut
700	1	a Tsegay, Amanuel T.4 aut
700	1	a Ullah, Irfan4 aut
700	1	a Venketasubramanian, Narayanaswamy4 aut
700	1	a Vlassov, Vasily4 aut
700	1	a Wang, Yuan-Pang4 aut
700	1	a Weiss, Jordan4 aut
700	1	a Westerman, Ronny4 aut
700	1	a Wijeratne, Tissa4 aut
700	1	a Wyper, Grant M. A.4 aut
700	1	a Yano, Yuichiro4 aut
700	1	a Yimer, Ebrahim M.4 aut
700	1	a Yonemoto, Naohiro4 aut
700	1	a Yousefifard, Mahmoud4 aut
700	1	a Zaidi, Zoubida4 aut
700	1	a Zare, Zohreh4 aut
700	1	a Feigin, Valery L.4 aut
700	1	a Vos, Theo4 aut
700	1	a Murray, Christopher J. L.4 aut
710	2	a Umeå universitetb Institutionen för omvårdnad4 org
773	0	t Lancet Neurologyd : Elsevierg 18:1, s. 88-106q 18:1<88-106x 1474-4422x 1474-4465
856	4	u https://doi.org/10.1016/S1474-4422(18)30403-4y Fulltext
856	4	u https://umu.diva-portal.org/smash/get/diva2:1379456/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-166521
856	4 8	u https://doi.org/10.1016/S1474-4422(18)30403-4
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:139843429

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Av författaren/redakt...: Nichols, Emma; Szoeke, Cassandr ...; Vollset, Stein E ...; Abbasi, Nooshin; Abd-Allah, Foad; Abdela, Jemal; visa fler...; Aichour, Miloud ...; Akinyemi, Rufus ...; Alahdab, Fares; Asgedom, Solomon ...; Awasthi, Ashish; Barker-Collo, Su ...; Baune, Bernhard ...; Bejot, Yannick; Belachew, Abate ...; Bennett, Derrick ...; Bijani, Belete B ...; Bin Sayeed, Muha ...; Brayne, Carol; Carpenter, David ...; Carvalho, Felix; Catala-Lopez, Fe ...; Cerin, Ester; Choi, Jee-Young ...; Dang, Ahn K.; Degefa, Meaza G.; Djalalinia, Shir ...; Dubey, Manisha; Duken, Eyasu Eje ...; Edvardsson, Davi ...; Endres, Matthias; Eskandarieh, Sha ...; Faro, Andre; Farzadfar, Farsh ...; Fereshtehnejad, ...; Fernandes, Eduar ...; Filip, Irina; Fischer, Florian; Gebre, Abadi K.; Geremew, Demeke; Ghasemi-Kasman, ...; Gnedovskaya, Ele ...; Gupta, Rajeev; Hachinski, Vladi ...; Hagos, Tekleberh ...; Hamidi, Samer; Hankey, Graeme J ...; Haro, Josep M.; Hay, Simon I.; Irvani, Seyed Si ...; Jha, Ravi P.; Jonas, Jost B.; Kalani, Rizwan; Karch, Andre; Kasaeian, Amir; Khader, Yousef S ...; Khalil, Ibrahim ...; Khan, Ejaz Ahmad; Khanna, Tripti; Khoja, Tawfik A. ...; Khubchandani, Ja ...; Kisa, Adnan; Kissimova-Skarbe ...; Kivimaki, Mika; Koyanagi, Ai; Krohn, Kristophe ...; Logroscino, Gian ...; Lorkowski, Stefa ...; Majdan, Marek; Malekzadeh, Reza; Marz, Winfried; Massano, Joao; Mengistu, Getnet; Meretoja, Atte; Mohammadi, Mosle ...; Mohammadi-Khanap ...; Mokdad, Ali H.; Mondello, Stefan ...; Moradi, Ghobad; Nagel, Gabriele; Naghavi, Mohsen; Naik, Gurudatta; Nguyen, Long H.; Nguyen, Trang H.; Nirayo, Yirga L.; Nixon, Molly R.; Ofori-Asenso, Ri ...; Ogbo, Felix A.; Olagunju, Andrew ...; Owolabi, Mayowa ...; Panda-Jonas, Son ...; Passos, Valeria ...; Pereira, David M ...; Pinilla-Monsalve ...; Piradov, Michael ...; Pond, Constance ...; Poustchi, Hossei ...; Qorbani, Mostafa; Radfar, Amir; Reiner, Robert C ...; Robinson, Stephe ...; Roshandel, Ghola ...; Rostami, Ali; Russ, Tom C.; Sachdev, Permind ...; Safari, Hosein; Safiri, Saeid; Sahathevan, Rame ...; Salimi, Yahya; Satpathy, Mahesw ...; Sawhney, Monika; Saylan, Mete; Sepanlou, Sadaf ...; Shafieesabet, Az ...; Shaikh, Masood A ...; Sahraian, Mohamm ...; Shigematsu, Mika; Shiri, Rahman; Shiue, Ivy; Silva, Joao P.; Smith, Mari; Sobhani, Soheila; Stein, Dan J.; Tabares-Seisdedo ...; Tovani-Palone, M ...; Tran, Bach X.; Tran, Tung T.; Tsegay, Amanuel ...; Ullah, Irfan; Venketasubramani ...; Vlassov, Vasily; Wang, Yuan-Pang; Weiss, Jordan; Westerman, Ronny; Wijeratne, Tissa; Wyper, Grant M. ...; Yano, Yuichiro; Yimer, Ebrahim M ...; Yonemoto, Naohir ...; Yousefifard, Mah ...; Zaidi, Zoubida; Zare, Zohreh; Feigin, Valery L ...; Vos, Theo; Murray, Christop ...; visa färre...

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