WFRF:(Andersen Leif)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03475naa a2200397 4500 | |
| 001 | oai:lup.lub.lu.se:a9b5342a-105e-4908-b468-2c1755d50cb1 | |
| 003 | SwePub | |
| 008 | 160401s2008 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/13775042 URI |
| 024 | 7 | a https://doi.org/10.3748/wjg.14.69542 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Aabenhus, Runeu Copenhagen University Hospital4 aut |
| 245 | 1 0 | a First attempt to produce experimental Campylobacter concisus infection in mice |
| 264 | 1 | b Baishideng Publishing Group Inc.c 2008 |
| 520 | a AIM: To infect mice with atypical Campylobacter concisus (C concisus) for the first time. METHODS: Three separate experiments were conducted in order to screen the ability of five clinical C concisus isolates of intestinal origin and the ATCC 33237 type strain of oral origin to colonize and produce infection in immunocompetent BALB/cA mice. The majority of the BALB/cA mice were treated with cyclophosphamide prior to C concisus inoculation to suppress immune functions. Inoculation of C concisus was performed by the gastric route. RESULTS: C concisus was isolated from the liver, ileum and jejunum of cyclophosphamide-treated mice in the first experiment. No C concisus strains were isolated in the two subsequent experiments. Mice infected with C concisus showed a significant loss of body weight from day two through to day five of infection but this decreased at the end of the first week. Histopathologicalexamination did not consistently find signs of inflammation in the gut, but occasionally microabscesses were found in the liver of infected animals. CONCLUSION: Transient colonization with C concisus was observed in mice with loss of body weight. Future studies should concentrate on the first few days after inoculation and in other strains of mice. (C) 2008 The WJG Press. All rights reserved. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng |
| 653 | a Campylobacter concisus | |
| 653 | a Animal model | |
| 653 | a BALB/cA mice | |
| 653 | a Infection | |
| 653 | a Colonization | |
| 700 | 1 | a Stenram, Unneu Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)pat-ust |
| 700 | 1 | a Andersen, Leif Percivalu Copenhagen University Hospital4 aut |
| 700 | 1 | a Permin, Henriku Bispebjerg Hospital4 aut |
| 700 | 1 | a Ljungh, Åsau Lund University,Lunds universitet,Avdelningen för medicinsk mikrobiologi,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Medical Microbiology,Department of Laboratory Medicine,Faculty of Medicine4 aut0 (Swepub:lu)mmb-alj |
| 710 | 2 | a Copenhagen University Hospitalb Tumörmikromiljö4 org |
| 773 | 0 | t World Journal of Gastroenterologyd : Baishideng Publishing Group Inc.g 14:45, s. 6954-6959q 14:45<6954-6959x 1007-9327 |
| 856 | 4 | u http://dx.doi.org/10.3748/wjg.14.6954y FULLTEXT |
| 856 | 4 | u https://doi.org/10.3748/wjg.14.6954 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/1377504 |
| 856 | 4 8 | u https://doi.org/10.3748/wjg.14.6954 |
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