Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: WFRF:(Engfeldt Peter) > Associations betwee...

LIBRIS Formathandbok (Information om MARC21)

Fältnamn	Indikatorer	Metadata
000		04356naa a2200565 4500
001		oai:DiVA.org:oru-9716
003		SwePub
008		100212s2009 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:umu-79790
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-97162 URI
024	7	a https://doi.org/10.1007/s00394-009-0058-22 DOI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-797902 URI
040		a (SwePub)orud (SwePub)umu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Almon, Ricardo,d 1965-u Örebro universitet,Institutionen för klinisk medicin,AFC4 aut0 (Swepub:oru)roan
245	1 0	a Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands
264		c 2009-10-22
264	1	a Heidelberg, Germany :b Springer,c 2009
338		a print2 rdacarrier
520		a Background: The single nucleotide polymorphism (SNP) LCT -13910 C>T, associated with genetically determined phenotypes of lactase persistence (LP) or non-persistence (LNP), was studied in relation to the metabolic syndrome (MS).AIim of the study: The aim was to determine if milk intake and MS are associated. We applied Mendelian randomization (MR). The SNP, LCT -13910 C>T, with the genotypes LP (TT/CT) and LNP (CC), was taken as a proxy for milk consumption.Methods: A representative sample of adults belonging to the Canary Islands Nutrition Survey (ENCA) in Spain aged 18-75 years (n = 551) was genotyped for the LCT -13910 C>T polymorphism. We used the International Diabetes Federation (IDF) criteria to define MS. RESULTS: 60% of the population was LP and 40% LNP. One hundred seven LP subjects (35.0%) and 53 LNP subjects (25.6%) showed MS (chi (2) = 5.04, p = 0.025). LP subjects showed a significantly higher odds ratio (OR) for MS than LNP subjects computed for the whole population: both the crude OR (1.56; 95% CI 1.06-2.31) and adjusted OR for sex, age, daily energy intake, physical activity and educational level (1.57; 95% CI 1.02-2.43). Adjusted OR for women with LP was 1.93; 95% CI 1.06-3.52.Conclusions: The T allele of the SNP might constitute a nutrigenetic factor increasing the susceptibility of LP subjects, especially women, to develop MS in the Canary Islands.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Fysiologi0 (SwePub)301062 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Physiology0 (SwePub)301062 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng
653		a LCT-13910 C > T polymorphism
653		a Metabolic syndrome
653		a Metabolic syndrome
653		a Milk
653		a Mendelian randomization
653		a MEDICINE
653		a MEDICIN
653		a Physiology
653		a Fysiologi
653		a Nutrition
653		a Näringslära
653		a Näringslära
653		a Nutrition
700	1	a Alvarez-Leon, Eva E.u Univ Las Palmas Gran Canaria, Fac Hlth Sci, Dept Clin Sci, Canary Isl, Spain; Hosp Insular Gran Canaria, Canarian Hlth Serv, Serv Prevent Med, Canary Isl, Spain4 aut
700	1	a Engfeldt, Peteru Örebro universitet,Institutionen för klinisk medicin,AFC4 aut0 (Swepub:oru)pet
700	1	a Serra-Majem, Lluisu Univ Las Palmas Gran Canaria, Fac Hlth Sci, Dept Clin Sci, Canary Isl, Spain; Hosp Insular Gran Canaria, Canarian Hlth Serv, Serv Prevent Med, Canary Isl, Spain4 aut
700	1	a Magnuson, Andersu Örebro University hospital, Örebro, Sweden,KFC USÖ4 aut
700	1	a Nilsson, Torbjörn K.u Örebro University hospital, Örebro, Sweden,Department of Clinical Chemistry, Örebro University Hospital4 aut0 (Swepub:umu)toni0049
710	2	a Örebro universitetb Institutionen för klinisk medicin4 org
773	0	t European Journal of Nutritiond Heidelberg, Germany : Springerg 49:3, s. 141-146q 49:3<141-146x 1436-6207x 1436-6215
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-9716
856	4 8	u https://doi.org/10.1007/s00394-009-0058-2
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-79790

Hitta via bibliotek

European Journal of Nutrition (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...: Almon, Ricardo, ...; Alvarez-Leon, Ev ...; Engfeldt, Peter; Serra-Majem, Llu ...; Magnuson, Anders; Nilsson, Torbjör ...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Medicinska och f ...; och Fysiologi

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Hälsovetenskap; och Näringslära

Artiklar i publikationen: European Journal ...

Av lärosätet: Örebro universitet; Umeå universitet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se