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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003923naa a2200445 4500
001oai:lup.lub.lu.se:7fe7b47e-5072-43fd-b903-f114ef75329f
003SwePub
008160401s2008 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/12472502 URI
024a https://doi.org/10.1111/j.1742-1241.2008.01872.x2 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Benner, J. S.4 aut
2451 0a A novel programme to evaluate and communicate 10-year risk of CHD reduces predicted risk and improves patients' modifiable risk factor profile
264 c 2008-08-07
264 1b Hindawi Limited,c 2008
520 a Aims: We assessed whether a novel programme to evaluate/communicate predicted coronary heart disease (CHD) risk could lower patients' predicted Framingham CHD risk vs. usual care. Methods: The Risk Evaluation and Communication Health Outcomes and Utilization Trial was a prospective, controlled, cluster-randomised trial in nine European countries, among patients at moderate cardiovascular risk. Following baseline assessments, physicians in the intervention group calculated patients' predicted CHD risk and were instructed to advise patients according to a risk evaluation/communication programme. Usual care physicians did not calculate patients' risk and provided usual care only. The primary end-point was Framingham 10-year CHD risk at 6 months with intervention vs. usual care. Results: Of 1103 patients across 100 sites, 524 patients receiving intervention, and 461 receiving usual care, were analysed for efficacy. After 6 months, mean predicted risks were 12.5% with intervention, and 13.7% with usual care [odds ratio = 0.896; p = 0.001, adjusted for risk at baseline (17.2% intervention; 16.9% usual care) and other covariates]. The proportion of patients achieving both blood pressure and low-density lipoprotein cholesterol targets was significantly higher with intervention (25.4%) than usual care (14.1%; p < 0.001), and 29.3% of smokers in the intervention group quit smoking vs. 21.4% of those receiving usual care (p = 0.04). Conclusions: A physician-implemented CHD risk evaluation/communication programme improved patients' modifiable risk factor profile, and lowered predicted CHD risk compared with usual care. By combining this strategy with more intensive treatment to reduce residual modifiable risk, we believe that substantial improvements in cardiovascular disease prevention could be achieved in clinical practice.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Annan klinisk medicin0 (SwePub)302992 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Other Clinical Medicine0 (SwePub)302992 hsv//eng
700a Erhardt, Leif RWu Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-ler
700a Flammer, M.4 aut
700a Moller, R. A.4 aut
700a Rajicic, N.4 aut
700a Changela, K.4 aut
700a Yunis, C.4 aut
700a Cherry, S. B.4 aut
700a Gaciong, Z.4 aut
700a Johnson, E. S.4 aut
700a Sturkenboom, M. C. J. M.4 aut
700a Garcia-Puig, J.4 aut
700a Girerd, X.4 aut
710a Internmedicin - epidemiologib Forskargrupper vid Lunds universitet4 org
773t International Journal of Clinical Practiced : Hindawi Limitedg 62:10, s. 1484-1498q 62:10<1484-1498x 1742-1241x 1368-5031
856u http://dx.doi.org/10.1111/j.1742-1241.2008.01872.xy FULLTEXT
856u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1742-1241.2008.01872.x
8564 8u https://lup.lub.lu.se/record/1247250
8564 8u https://doi.org/10.1111/j.1742-1241.2008.01872.x

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