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Patient educational level and use of newly marketed drugs : a register-based study of over 600,000 older people

Haider, Syed Imran (författare)
Johnell, Kristina (författare)
Karolinska Institutet
Weitoft, Gunilla Ringback (författare)
visa fler...
Thorslund, Mats (författare)
Karolinska Institutet,Stockholms universitet,Institutionen för socialt arbete - Socialhögskolan
Fastbom, Johan (författare)
Karolinska Institutet
visa färre...
 (creator_code:org_t)
2008-08-10
2008
Engelska.
Ingår i: European Journal of Clinical Pharmacology. - : Springer Science and Business Media LLC. - 0031-6970 .- 1432-1041. ; 64:12, s. 1215-1222
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Objective To examine the association between educational level and the use of newly marketed drugs (NMD) among elderly persons. Methods We conducted a register-based, retrospective, cross-sectional study of 626,258 people aged 75-89 years who filled at least one drug prescription from August to October 2005 and who, consequently, were registered in the Swedish Prescribed Drug Register (SPDR). Data from the SPDR were record-linked to the Swedish National Inpatient Register and the Education Register. Newly marketed drugs were defined as new chemical entities that had been approved in Sweden between 2000 and 2004. Results Overall, NMD were prescribed to 7.3% of the study population. The use of NMD increased with increasing educational level (6.9% for the lowest educated elderly and 8.1% for the highest educated elderly), and education was associated with NMD [odds ratio (OR) 0.82; 95% confidence interval (CI)] 0.80-0.88 for <9 compared with >= 13 years of education) after adjustment for age, sex, type of residential area and number of dispensed drugs. Decreasing educational level was associated with a lower probability of using most of the NMD, especially oseltamivir (adjusted OR 0.16; 95% CI 0.12-0.22 for <9 years of education compared with >= 13 years of education) and ezetimibe. Conclusions This study suggests that education-related inequalities in NMD use may exist even in a healthcare system that claims to ensure a high degree of equity. Future research is required to explain why educational level influences the selection of new drugs and whether it has any impact on health outcomes.

Nyckelord

Education
Elderly
Equity
New drugs
Registers
Socioeconomic position
general-practitioners
prescription
polypharmacy
inequalities
medication
rofecoxib
adoption
sweden
health
canada
Social sciences
Socialvetenskap

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