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Characteristics of patients making serious inhaler errors with a dry powder inhaler and association with asthma-related events in a primary care setting
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- Westerik, Janine A. M. (author)
- Res Real Life Ltd, Cambridge, England.
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- Carter, Victoria (author)
- Optimum Patient Care Ltd, Cambridge, England.
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- Chrystyn, Henry (author)
- Res Real Life Ltd, Cambridge, England.;Inhalat Consultancy Ltd, Leeds, W Yorkshire, England.
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- Burden, Anne (author)
- Res Real Life Ltd, Cambridge, England.
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- Thompson, Samantha L. (author)
- Res Real Life Ltd, Cambridge, England.
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- Ryan, Dermot (author)
- Woodbrook Med Ctr, Loughborough, Leics, England.;Univ Edinburgh, Ctr Populat Hlth Sci, Edinburgh EH8 9YL, Midlothian, Scotland.
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Gruffydd-Jones, Kevin (author)
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- Haughney, John (author)
- Univ Aberdeen, Acad Primary Care, Polwarth Bldg, Aberdeen AB25 2ZD, Scotland.
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- Roche, Nicolas (author)
- Univ Paris 05, Cochin Hosp Grp, AP HP, EA2511, Paris, France.
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- Lavorini, Federico (author)
- Careggi Univ Hosp, Dept Expt & Clin Med, Florence, Italy.
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- Papi, Alberto (author)
- Univ Ferrara, Dept Med Sci, I-44100 Ferrara, Italy.
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- Infantino, Antonio (author)
- Soc Italiana Interdisciplinare Cure Primarie, Special Interest Resp Area, Bari, Italy.
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- Roman-Rodriguez, Miguel (author)
- Inst Invest Sanitaria Palma IdisPa, Primary Care Resp Res Unit, Palma De Mallorca, Spain.
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- Bosnic-Anticevich, Sinthia (author)
- Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia.;Univ Sydney, Woolcock Inst Med Res, Sydney, NSW 2006, Australia.
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- Lisspers, Karin (author)
- Uppsala universitet,Allmänmedicin och preventivmedicin
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- Ställberg, Björn (author)
- Uppsala universitet,Allmänmedicin och preventivmedicin
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- Henrichsen, Svein Hoegh (author)
- Univ Oslo, Dept Gen Med, N-0316 Oslo, Norway.;Langbolgen Legesenter, London, England.
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- van der Molen, Thys (author)
- Univ Groningen, Univ Med Ctr Groningen, Dept Primary Care, Groningen, Netherlands.
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- Hutton, Catherine (author)
- Res Real Life Ltd, Cambridge, England.
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- Price, David B. (author)
- Res Real Life Ltd, Cambridge, England.;Univ Aberdeen, Acad Primary Care, Polwarth Bldg, Aberdeen AB25 2ZD, Scotland.
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Res Real Life Ltd, Cambridge, England Optimum Patient Care Ltd, Cambridge, England. (creator_code:org_t)
- 2016-01-26
- 2016
- English.
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In: Journal of Asthma. - : Informa UK Limited. - 0277-0903 .- 1532-4303. ; 53:3, s. 321-329
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Abstract
Subject headings
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- Objective: Correct inhaler technique is central to effective delivery of asthma therapy. The study aim was to identify factors associated with serious inhaler technique errors and their prevalence among primary care patients with asthma using the Diskus dry powder inhaler (DPI).Methods: This was a historical, multinational, cross-sectional study (2011-2013) using the iHARP database, an international initiative that includes patient- and healthcare provider-reported questionnaires from eight countries. Patients with asthma were observed for serious inhaler errors by trained healthcare providers as predefined by the iHARP steering committee. Multivariable logistic regression, stepwise reduced, was used to identify clinical characteristics and asthma-related outcomes associated with 1 serious errors.Results: Of 3681 patients with asthma, 623 (17%) were using a Diskus (mean [SD] age, 51 [14]; 61% women). A total of 341 (55%) patients made 1 serious errors. The most common errors were the failure to exhale before inhalation, insufficient breath-hold at the end of inhalation, and inhalation that was not forceful from the start. Factors significantly associated with 1 serious errors included asthma-related hospitalization the previous year (odds ratio [OR] 2.07; 95% confidence interval [CI], 1.26-3.40); obesity (OR 1.75; 1.17-2.63); poor asthma control the previous 4 weeks (OR 1.57; 1.04-2.36); female sex (OR 1.51; 1.08-2.10); and no inhaler technique review during the previous year (OR 1.45; 1.04-2.02).Conclusions: Patients with evidence of poor asthma control should be targeted for a review of their inhaler technique even when using a device thought to have a low error rate.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Keyword
- Asthma therapy
- cross-sectional
- Diskus inhaler
- inhalation devices
- multinational
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Westerik, Janine ...
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Carter, Victoria
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Chrystyn, Henry
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Burden, Anne
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Thompson, Samant ...
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Ryan, Dermot
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Gruffydd-Jones, ...
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Haughney, John
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Roche, Nicolas
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Lavorini, Federi ...
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Papi, Alberto
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Infantino, Anton ...
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Roman-Rodriguez, ...
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Bosnic-Anticevic ...
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Lisspers, Karin
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Ställberg, Björn
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Henrichsen, Svei ...
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van der Molen, T ...
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Hutton, Catherin ...
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Price, David B.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Respiratory Medi ...
- Articles in the publication
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Journal of Asthm ...
- By the university
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Uppsala University