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WFRF:(Munshi S)
 

Sökning: WFRF:(Munshi S) > (2010-2014) > International Myelo...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004134naa a2200517 4500
001oai:lup.lub.lu.se:9dc38650-38dd-4f21-afc4-ea95ae6c8fab
003SwePub
008160401s2013 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/38043002 URI
0247 a https://doi.org/10.1200/JCO.2012.47.79012 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Terpos, Evangelos4 aut
2451 0a International Myeloma Working Group Recommendations for the Treatment of Multiple Myeloma-Related Bone Disease.
264 1c 2013
520 a PURPOSEThe aim of the International Myeloma Working Group was to develop practice recommendations for the management of multiple myeloma (MM) -related bone disease.MethodologyAn interdisciplinary panel of clinical experts on MM and myeloma bone disease developed recommendations based on published data through August 2012. Expert consensus was used to propose additional recommendations in situations where there were insufficient published data. Levels of evidence and grades of recommendations were assigned and approved by panel members.RecommendationsBisphosphonates (BPs) should be considered in all patients with MM receiving first-line antimyeloma therapy, regardless of presence of osteolytic bone lesions on conventional radiography. However, it is unknown if BPs offer any advantage in patients with no bone disease assessed by magnetic resonance imaging or positron emission tomography/computed tomography. Intravenous (IV) zoledronic acid (ZOL) or pamidronate (PAM) is recommended for preventing skeletal-related events in patients with MM. ZOL is preferred over oral clodronate in newly diagnosed patients with MM because of its potential antimyeloma effects and survival benefits. BPs should be administered every 3 to 4 weeks IV during initial therapy. ZOL or PAM should be continued in patients with active disease and should be resumed after disease relapse, if discontinued in patients achieving complete or very good partial response. BPs are well tolerated, but preventive strategies must be instituted to avoid renal toxicity or osteonecrosis of the jaw. Kyphoplasty should be considered for symptomatic vertebral compression fractures. Low-dose radiation therapy can be used for palliation of uncontrolled pain, impending pathologic fracture, or spinal cord compression. Orthopedic consultation should be sought for long-bone fractures, spinal cord compression, and vertebral column instability.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
7001 a Morgan, Gareth4 aut
7001 a Dimopoulos, Meletios A4 aut
7001 a Drake, Matthew T4 aut
7001 a Lentzsch, Suzanne4 aut
7001 a Raje, Noopur4 aut
7001 a Sezer, Orhan4 aut
7001 a García-Sanz, Ramón4 aut
7001 a Shimizu, Kazuyuki4 aut
7001 a Turesson, Ingemaru Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine4 aut0 (Swepub:lu)medf-itu
7001 a Reiman, Tony4 aut
7001 a Jurczyszyn, Artur4 aut
7001 a Merlini, Giampaolo4 aut
7001 a Spencer, Andrew4 aut
7001 a Leleu, Xavier4 aut
7001 a Cavo, Michele4 aut
7001 a Munshi, Nikhil4 aut
7001 a Rajkumar, S Vincent4 aut
7001 a Durie, Brian G M4 aut
7001 a Roodman, G David4 aut
7102 a Institutionen för kliniska vetenskaper, Malmöb Medicinska fakulteten4 org
7730 t Journal of Clinical Oncologyg 31:18, s. 179-2347q 31:18<179-2347x 1527-7755
8564 u http://www.ncbi.nlm.nih.gov/pubmed/23690408?dopt=Abstracty FULLTEXT
8564 u http://dx.doi.org/10.1200/JCO.2012.47.7901y FULLTEXT
8564 8u https://lup.lub.lu.se/record/3804300
8564 8u https://doi.org/10.1200/JCO.2012.47.7901

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