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WFRF:(Ochoa Figueroa Miguel)
 

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005502naa a2200673 4500
001oai:DiVA.org:liu-178770
003SwePub
008210901s2021 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:147344356
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1787702 URI
024a https://doi.org/10.1002/alz.122942 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1473443562 URI
040 a (SwePub)liud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Bauckneht, Matteou IRCCS Osped Policlin San Martino, Italy4 aut
2451 0a Associations among education, age, and the dementia with Lewy bodies (DLB) metabolic pattern: A European-DLB consortium project
264 c 2021-02-02
264 1b WILEY,c 2021
338 a print2 rdacarrier
520 a Introduction We assessed the influence of education as a proxy of cognitive reserve and age on the dementia with Lewy bodies (DLB) metabolic pattern. Methods Brain 18F-fluorodeoxyglucose positron emission tomography and clinical/demographic information were available in 169 probable DLB patients included in the European DLB-consortium database. Principal component analysis identified brain regions relevant to local data variance. A linear regression model was applied to generate age- and education-sensitive maps corrected for Mini-Mental State Examination score, sex (and either education or age). Results Age negatively covaried with metabolism in bilateral middle and superior frontal cortex, anterior and posterior cingulate, reducing the expression of the DLB-typical cingulate island sign (CIS). Education negatively covaried with metabolism in the left inferior parietal cortex and precuneus (making the CIS more prominent). Discussion These findings point out the importance of tailoring interpretation of DLB biomarkers considering the concomitant effect of individual, non-disease-related variables such as age and cognitive reserve.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Geriatrik0 (SwePub)302222 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Geriatrics0 (SwePub)302222 hsv//eng
653 a biomarkers; cognitive reserve; dementia with Lewy bodies; fluorodeoxyglucose positron emission tomography
700a Chincarini, Andreau Natl Inst Nucl Phys INFN, Italy4 aut
700a Brendel, Matthiasu Ludwig Maximilians Univ Munchen, Germany4 aut
700a Rominger, Axelu Ludwig Maximilians Univ Munchen, Germany; Univ Hosp Bern, Switzerland4 aut
700a Beyer, Leonieu Ludwig Maximilians Univ Munchen, Germany4 aut
700a Bruffaerts, Roseu Katholieke Univ Leuven, Belgium; Univ Hosp Leuven, Belgium; Hasselt Univ, Belgium4 aut
700a Vandenberghe, Riku Katholieke Univ Leuven, Belgium; Univ Hosp Leuven, Belgium4 aut
700a Kramberger, Milica G.u Univ Med Ctr Ljubljana, Slovenia; Univ Ljubljana, Slovenia4 aut
700a Trost, Majau Univ Med Ctr Ljubljana, Slovenia; Univ Ljubljana, Slovenia4 aut
700a Garibotto, Valentinau Univ Geneva, Switzerland; Univ Geneva, Switzerland4 aut
700a Nicastro, Nicolasu Geneva Univ Hosp, Switzerland; Univ Cambridge, England4 aut
700a Frisoni, Giovanni B.u Geneva Univ Hosp, Switzerland4 aut
700a Lemstra, Afina W.u Vrije Univ Amsterdam, Netherlands4 aut
700a Berckel, Bart N. M.u Vrije Univ Amsterdam, Netherlands4 aut
700a Pilotto, Andreau Univ Brescia, Italy; Isidoro Hosp, Italy4 aut
700a Padovani, Alessandrou Univ Brescia, Italy4 aut
700a Ochoa-Figueroa, Miguel A.u Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Röntgenkliniken i Linköping,Region Östergötland, Fysiologiska kliniken US4 aut0 (Swepub:liu)n/a
700a Davidsson, Anetteu Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Fysiologiska kliniken US4 aut0 (Swepub:liu)aneda83
700a Camacho, Valleu Univ Autonoma Barcelona, Spain4 aut
700a Peira, Enricou Natl Inst Nucl Phys INFN, Italy; Univ Genoa, Italy4 aut
700a Arnaldi, Dariou Univ Genoa, Italy; IRCCS Osped Policlin San Martino, Italy4 aut
700a Pardini, Matteou Univ Genoa, Italy; IRCCS Osped Policlin San Martino, Italy4 aut
700a Donegani, Maria Isabellau Univ Genoa, Italy4 aut
700a Raffa, Stefanou Univ Genoa, Italy4 aut
700a Miceli, Albertou Univ Genoa, Italy4 aut
700a Sambuceti, Gianmariou IRCCS Osped Policlin San Martino, Italy; Univ Genoa, Italy4 aut
700a Aarsland, Dagu Karolinska Institutet4 aut
700a Nobili, Flaviou Univ Genoa, Italy; IRCCS Osped Policlin San Martino, Italy4 aut
700a Morbelli, Silviau IRCCS Osped Policlin San Martino, Italy; Univ Genoa, Italy4 aut
710a IRCCS Osped Policlin San Martino, Italyb Natl Inst Nucl Phys INFN, Italy4 org
773t Alzheimer's & Dementiad : WILEYg 17:8, s. 1277-1286q 17:8<1277-1286x 1552-5260x 1552-5279
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-178770
8564 8u https://doi.org/10.1002/alz.12294
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:147344356

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