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Secondary Le Fort III after Early Fronto-Facial Monobloc Normalizes Sleep Apnea in Faciocraniosynostosis : A Cohort Study

Haber, Samer E. (författare)
Univ Paris, Assistance Publ Hop Paris, Hop Necker Enfants Malad, Serv Neurochirurg Pediat,Unite Fonctionnelle Chiru, Paris, France.;Univ Paris, Ctr Reference Malad Rares CRANIOST, Filiere Malad Rares Tete Cou, Paris, France.
Leikola, Junnu (författare)
Univ Helsinki, Toolo Hosp,Cent Hosp, Cleft Palate & Craniofacial Ctr, Dept Plast Surg, POB 266, FI-00029 Helsinki, Finland.
Nowinski, Daniel (författare)
Uppsala universitet,Plastikkirurgi
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Fauroux, Brigitte (författare)
Univ Sorbonne Paris Cite, Serv Ventilat Noninvas & Sommeil delEnfant, Paris, France.;Univ Sorbonne Paris Cite, Assistance Publ Hop Paris, Hop Univ Necker Enfants Malad, Paris, France.;Univ Sorbonne Paris Cite, VIFASOM Vigilance Fatigue Sommeilet St Publ EA7330, Paris, France.;Univ Paris 05, Univ Sorbonne Paris C, Descartes, Paris, France.
Morisseau-Durand, Marie-Paule (författare)
Univ Paris 05, Hop Necker Enfants Malad, Assistance Publ Hop Paris, Serv Otorhinolaryngol Pediat, Paris, France.;Univ Paris 05, Ctr Reference Malad Rares MALO, Filiere Malad Rares TeteCou, Paris, France.;Univ Paris, Univ Paris Descartes, Paris, France.
Paternoster, Giovanna (författare)
Univ Paris, Assistance Publ Hop Paris, Hop Necker Enfants Malad, Serv Neurochirurg Pediat,Unite Fonctionnelle Chiru, Paris, France.;Univ Paris, Ctr Reference Malad Rares CRANIOST, Filiere Malad Rares Tete Cou, Paris, France.
Khonsari, Roman H. (författare)
Univ Paris, Ctr Reference Malad Rares CRANIOST, Filiere Malad Rares Tete Cou, Paris, France.;Univ Paris, Hop Necker Enfants Malad, Assistance Publ Hop Paris, Serv Chirurg maxillofaciale & Chirurg plast, Paris, France.
Arnaud, Eric (författare)
Univ Paris, Assistance Publ Hop Paris, Hop Necker Enfants Malad, Serv Neurochirurg Pediat,Unite Fonctionnelle Chiru, Paris, France.;Univ Paris, Ctr Reference Malad Rares CRANIOST, Filiere Malad Rares Tete Cou, Paris, France.;Clin Marcel Sembat, F-92100 Boulogne, France.;Hop Necker Enfants Malad, Serv Neurochirurg Pediat, Unite fonct Chirurg craniofaciale, 34 Ave Eylau, F-75116 Paris, France.
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Univ Paris, Assistance Publ Hop Paris, Hop Necker Enfants Malad, Serv Neurochirurg Pediat,Unite Fonctionnelle Chiru, Paris, France;Univ Paris, Ctr Reference Malad Rares CRANIOST, Filiere Malad Rares Tete Cou, Paris, France. Univ Helsinki, Toolo Hosp,Cent Hosp, Cleft Palate & Craniofacial Ctr, Dept Plast Surg, POB 266, FI-00029 Helsinki, Finland. (creator_code:org_t)
Elsevier, 2022
2022
Engelska.
Ingår i: Journal of Plastic, Reconstructive & Aesthetic Surgery. - : Elsevier. - 1748-6815 .- 1878-0539. ; 75:8, s. 2706-2718
Relaterad länk:
https://urn.kb.se/re...
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https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background: This study aims to assess the improvement of sleep apnea after sec-ondary Le Fort III facial advancement with distraction (LF3) in faciocraniosynostosis (FCS) pa-tients with sleep apnea who have previously undergone fronto-facial monobloc advancement (FFMBA) with distraction.Methods: Patients having undergone secondary LF3 were selected from a cohort of FCS pa-tients with documented sleep apnea who had previously undergone fronto-facial monobloc advancement. Patient charts and polysomnographic records were reviewed. Apnea-hypopnea index (AHI) was recorded before and at least 6 months after secondary LF3. The primary out-come was normalization of AHI (less than 5/h was considered normal). Hierarchical multilevel analysis was performed to predict postoperative AHI evolution.Results: Seventeen patients underwent a secondary LF3, 7.0 +/- 3.9 years after the primary FFMBA. The mean age was 9.6 +/- 3.9 years. A total of 15 patients (88%) normalized their AHI. Two of four patients were decannulated (50%). There was a statistically significant decrease in AHI (preoperative AHI 21.5/h vs. 3.9/h postoperatively, p = 0.003). Hierarchic multilevel mod-eling showed progressive AHI decrease postoperatively.Conclusion: Secondary LF3 improves residual or relapsing sleep apnea in FCS patients who have previously had FFMBA.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)

Nyckelord

Syndromic craniosynostosis
faciocraniosynostosis
facial advancement
distraction
sleep apnea
craniofacial osteotomy
FGFR
AHI

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