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Effects of dietary ...
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Ohman, E. A.
(författare)
Effects of dietary and exercise treatments on HDL subclasses in lactating women with overweight and obesity: a secondary analysis of a randomised controlled trial
- Artikel/kapitelEngelska2022
Förlag, utgivningsår, omfång ...
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2022-01-24
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Cambridge University Press (CUP),2022
Nummerbeteckningar
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LIBRIS-ID:oai:gup.ub.gu.se/314129
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https://gup.ub.gu.se/publication/314129URI
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https://doi.org/10.1017/s0007114522000241DOI
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Childbearing decreases HDL-cholesterol, potentially contributing to the increased risk of CVD in parous women. Large HDL particles (HDL-P) are associated with lower risk of CVD. In this secondary analysis of a randomised controlled trial, we investigated the effects of 12-week dietary and exercise treatments on HDL-P subclass concentration, size and apoA1 in lactating women with overweight/obesity. At 10-14 weeks postpartum, 68 women with pre-pregnant BMI 25-35 kg/m(2) were randomised to four groups using 2 x 2 factorial design: (1) dietary treatment for weight loss; (2) exercise treatment; (3) both treatments and (4) no treatment. Lipoprotein subclass profiling by NMR spectroscopy was performed in serum at randomisation and after 3 and 12 months, and the results analysed with two-way ANCOVA. Lipid concentrations decline naturally postpartum. At 3 months (5-6 months postpartum), both diet (P = 0 center dot 003) and exercise (P = 0 center dot 008) reduced small HDL-P concentration. Concurrently, exercise limited the decline in very large HDL-P (P = 0 center dot 002) and the effect was still significant at 12 months (15 months postpartum) (P = 0 center dot 041). At 12 months, diet limited the decline in very large HDL-P (P = 0 center dot 005), large HDL-P (P = 0 center dot 001) and apoA1 (P = 0 center dot 002) as well as HDL size (P = 0 center dot 002). The dietary treatment for weight loss and the exercise treatment both showed effects on HDL-P subclasses in lactating women with overweight and obesity possibly associated with lower CVD risk. The dietary treatment had more effects than the exercise treatment at 12 months, likely associated with a 10 % weight loss.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Kirchner, L.
(författare)
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Winkvist, Anna,1962Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition(Swepub:gu)xwinan
(författare)
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Bertz, FredrikGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition(Swepub:gu)xbertf
(författare)
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Holven, K. B.
(författare)
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Ulven, S. M.
(författare)
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Brekke, Hilde Kristin,1972Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition(Swepub:gu)xbrehi
(författare)
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Göteborgs universitetInstitutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:British Journal of Nutrition: Cambridge University Press (CUP)128:11, s. 2105-21140007-11451475-2662
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