Search: WFRF:(Pellettieri L) > Boron neutron captu...
Fältnamn | Indikatorer | Metadata |
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000 | 02189naa a2200337 4500 | |
001 | oai:gup.ub.gu.se/162116 | |
003 | SwePub | |
008 | 240528s2011 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/1621162 URI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Hopewell, JW4 aut |
245 | 1 0 | a Boron neutron capture therapy for newly diagnosed glioblastoma multiforme: An assessment of clinical potential |
264 | 1 | c 2011 |
520 | a Abstract: The purpose of this analysis was to assess the potential of BNCT, with L-boronophenylalanine (L-BPA), as first line radiotherapy for glioblastoma multiforme (GBM). The survival of patients with newly diagnosed GBM from a phase II BNCT study was compared with those from the two arms of a phase Ill study with conventional radiotherapy (RT) vs. RT plus concomitant and adjuvant medication with temozolomide (TMZ). A small subgroup, for which the methylation status of the O(6)-methylguanine-DNA methyltransferase (MGMT) DNA-repair gene was known, was also considered. The results indicated that the use of BNCT with BPA should be explored in a stratified randomized phase II trial in which patients with the unmethylated MGMT DNA-repair gene are offered BNCT vs. RT plus TMZ. (C) 2011 Elsevier Ltd. All rights reserved. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
653 | a newly diagnosed glioblastoma | |
653 | a bnct | |
653 | a clinical efficacy | |
700 | 1 | a Gorlia, T4 aut |
700 | 1 | a Pellettieri, Lu Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology4 aut |
700 | 1 | a Giusti, V4 aut |
700 | 1 | a H-Stenstam, B4 aut |
700 | 1 | a Skold, K4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi4 org |
773 | 0 | t APPLIED RADIATION AND ISOTOPESg 69:12, s. 1737-1740q 69:12<1737-1740x 0969-8043 |
856 | 4 8 | u https://gup.ub.gu.se/publication/162116 |
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