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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002189naa a2200337 4500
001oai:gup.ub.gu.se/162116
003SwePub
008240528s2011 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/1621162 URI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Hopewell, JW4 aut
2451 0a Boron neutron capture therapy for newly diagnosed glioblastoma multiforme: An assessment of clinical potential
264 1c 2011
520 a Abstract: The purpose of this analysis was to assess the potential of BNCT, with L-boronophenylalanine (L-BPA), as first line radiotherapy for glioblastoma multiforme (GBM). The survival of patients with newly diagnosed GBM from a phase II BNCT study was compared with those from the two arms of a phase Ill study with conventional radiotherapy (RT) vs. RT plus concomitant and adjuvant medication with temozolomide (TMZ). A small subgroup, for which the methylation status of the O(6)-methylguanine-DNA methyltransferase (MGMT) DNA-repair gene was known, was also considered. The results indicated that the use of BNCT with BPA should be explored in a stratified randomized phase II trial in which patients with the unmethylated MGMT DNA-repair gene are offered BNCT vs. RT plus TMZ. (C) 2011 Elsevier Ltd. All rights reserved.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng
653 a newly diagnosed glioblastoma
653 a bnct
653 a clinical efficacy
700a Gorlia, T4 aut
700a Pellettieri, Lu Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology4 aut
700a Giusti, V4 aut
700a H-Stenstam, B4 aut
700a Skold, K4 aut
710a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi4 org
773t APPLIED RADIATION AND ISOTOPESg 69:12, s. 1737-1740q 69:12<1737-1740x 0969-8043
8564 8u https://gup.ub.gu.se/publication/162116

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Hopewell, JW
Gorlia, T
Pellettieri, L
Giusti, V
H-Stenstam, B
Skold, K
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
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APPLIED RADIATIO ...
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University of Gothenburg

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