Reaction of a Phospholipid Monolayer with Gas-Phase Ozone at the Air-Water Interface: Measurement of Surface Excess and Surface Pressure in Real Time

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: WFRF:(Rennie Adrian R.) > Reaction of a Phosp...

Details
MARC

Thompson, Katherine C. (author)

Reaction of a Phospholipid Monolayer with Gas-Phase Ozone at the Air-Water Interface : Measurement of Surface Excess and Surface Pressure in Real Time

Article/chapterEnglish2010

Publisher, publication year, extent ...

2010-10-01
American Chemical Society (ACS),2010
printrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:uu-140034
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-140034URI
https://doi.org/10.1021/la1022714DOI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

The reaction between gas-phase ozone and monolayers of the unsaturated lipid 1-palmitoy1-2-oleoyl-sn-glycero-3-phosphocholine, POPC, on aqueous solutions has been studied in real time using neutron reflection and surface pressure measurements. The reaction between ozone and lung surfactant, which contains POPC, leads to decreased pulmonary function, but little is known shout the changes that occur to the interfacial material as a result of oxidation. The results reveal that the initial reaction of ozone with POPC leads to a rapid increase in surface pressure followed by a slow decrease to very low values. The neutron reflection measurements, performed on an isotopologue of POPC with a selectively deuterated palmitoyl strand, reveal that the reaction leads to loss of this strand from the air-water interface. suggesting either solubilization of the product lipid or degradation of the palmitoyl strand by a reactive species. Reactions of H-1-POPC on D2O reveal that the headgroup region of the lipids in aqueous solution is not dramatically perturbed by the reaction of POPC monolayers with ozone supporting degradation of the palmitoyl strand rather than solubilization. The results are consistent with the reaction of ozone with the oleoyl strand of POPC at the air water interface leading to the formation of OH radicals. the highly reactive OH radicals produced can then go on to react with the saturated palmitoyl strands leading to the formation or oxidized lipids with shorter alkyl tails.

Subject headings and genre

NATURVETENSKAP Fysik hsv//swe
NATURAL SCIENCES Physical Sciences hsv//eng
Physics
Fysik

Added entries (persons, corporate bodies, meetings, titles ...)

Rennie, Adrian R.Uppsala universitet,Institutionen för fysik och astronomi(Swepub:uu)adren227 (author)
King, Martin D. (author)
Hardman, Samantha J. O. (author)
Lucas, Claire O. M. (author)
Pfrang, Christian (author)
Hughes, Brian R. (author)
Hughes, Arwel V. (author)
Uppsala universitetInstitutionen för fysik och astronomi (creator_code:org_t)

Related titles

In:Langmuir: American Chemical Society (ACS)26:22, s. 17295-173030743-74631520-5827

Internet link

Find in a library

Langmuir (Search for host publication in LIBRIS)

To the university's database

Find more in SwePub

By the author/editor: Thompson, Kather ...; Rennie, Adrian R ...; King, Martin D.; Hardman, Samanth ...; Lucas, Claire O. ...; Pfrang, Christia ...; show more...; Hughes, Brian R.; Hughes, Arwel V.; show less...

About the subject

NATURAL SCIENCES: NATURAL SCIENCES; and Physical Science ...

Articles in the publication: Langmuir

By the university: Uppsala University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se