Reaction of a Phospholipid Monolayer with Gas-Phase Ozone at the Air-Water Interface: Measurement of Surface Excess and Surface Pressure in Real Time

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: WFRF:(Rennie Adrian R.) > Reaction of a Phosp...

LIBRIS Formathandbok (Information om MARC21)

Fältnamn	Indikatorer	Metadata
000		03143naa a2200397 4500
001		oai:DiVA.org:uu-140034
003		SwePub
008		110103s2010 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1400342 URI
024	7	a https://doi.org/10.1021/la10227142 DOI
040		a (SwePub)uu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Thompson, Katherine C.4 aut
245	1 0	a Reaction of a Phospholipid Monolayer with Gas-Phase Ozone at the Air-Water Interface :b Measurement of Surface Excess and Surface Pressure in Real Time
264		c 2010-10-01
264	1	b American Chemical Society (ACS),c 2010
338		a print2 rdacarrier
520		a The reaction between gas-phase ozone and monolayers of the unsaturated lipid 1-palmitoy1-2-oleoyl-sn-glycero-3-phosphocholine, POPC, on aqueous solutions has been studied in real time using neutron reflection and surface pressure measurements. The reaction between ozone and lung surfactant, which contains POPC, leads to decreased pulmonary function, but little is known shout the changes that occur to the interfacial material as a result of oxidation. The results reveal that the initial reaction of ozone with POPC leads to a rapid increase in surface pressure followed by a slow decrease to very low values. The neutron reflection measurements, performed on an isotopologue of POPC with a selectively deuterated palmitoyl strand, reveal that the reaction leads to loss of this strand from the air-water interface. suggesting either solubilization of the product lipid or degradation of the palmitoyl strand by a reactive species. Reactions of H-1-POPC on D2O reveal that the headgroup region of the lipids in aqueous solution is not dramatically perturbed by the reaction of POPC monolayers with ozone supporting degradation of the palmitoyl strand rather than solubilization. The results are consistent with the reaction of ozone with the oleoyl strand of POPC at the air water interface leading to the formation of OH radicals. the highly reactive OH radicals produced can then go on to react with the saturated palmitoyl strands leading to the formation or oxidized lipids with shorter alkyl tails.
650	7	a NATURVETENSKAPx Fysik0 (SwePub)1032 hsv//swe
650	7	a NATURAL SCIENCESx Physical Sciences0 (SwePub)1032 hsv//eng
653		a Physics
653		a Fysik
700	1	a Rennie, Adrian R.u Uppsala universitet,Institutionen för fysik och astronomi4 aut0 (Swepub:uu)adren227
700	1	a King, Martin D.4 aut
700	1	a Hardman, Samantha J. O.4 aut
700	1	a Lucas, Claire O. M.4 aut
700	1	a Pfrang, Christian4 aut
700	1	a Hughes, Brian R.4 aut
700	1	a Hughes, Arwel V.4 aut
710	2	a Uppsala universitetb Institutionen för fysik och astronomi4 org
773	0	t Langmuird : American Chemical Society (ACS)g 26:22, s. 17295-17303q 26:22<17295-17303x 0743-7463x 1520-5827
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-140034
856	4 8	u https://doi.org/10.1021/la1022714

Hitta via bibliotek

Langmuir (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...: Thompson, Kather ...; Rennie, Adrian R ...; King, Martin D.; Hardman, Samanth ...; Lucas, Claire O. ...; Pfrang, Christia ...; visa fler...; Hughes, Brian R.; Hughes, Arwel V.; visa färre...

Om ämnet

NATURVETENSKAP: NATURVETENSKAP; och Fysik

Artiklar i publikationen: Langmuir

Av lärosätet: Uppsala universitet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se