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Low stress resilien...
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Kennedy, Beatrice,1982-Uppsala universitet,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden,Clinical Epidemiology and Biostatistics,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab,Örebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70281 Örebro, Sweden
(författare)
Low stress resilience in late adolescence and risk of smoking, high alcohol consumption and drug use later in life
- Artikel/kapitelEngelska2019
Förlag, utgivningsår, omfång ...
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2019-02-04
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BMJ Publishing Group Ltd,2019
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:oru-72375
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-72375URI
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https://doi.org/10.1136/jech-2018-211815DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-390029URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:141197679URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Funding Agencies:European Research Council Consolidator Grant 726413 Swedish Council for Information on Alcohol and Other Drugs 2017-0095 Karolinska Institutet through a Senior Researcher Award Karolinska Institutet through a Strategic Research Area in Epidemiology Award
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De två första författarna delar förstaförfattarskapet.
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BACKGROUND: While compromised stress resilience constitutes a recognised risk factor for somatic and psychiatric disease development in general, the knowledge about how individual variation in vulnerability to stress may specifically influence the long-term risks of disadvantageous health behaviours is limited.METHODS: In this Swedish cohort study, we aimed to investigate the association between stress resilience in late adolescence and adult use of addictive substances. We included 9381 men with information on psychological stress resilience measured during military conscription examinations, who later responded to an extensive health survey (mean age 34.0±7.2 years) including detailed information on substance use. We modelled continuous outcomes using linear regression, binary outcomes with logistic regression and other categorical outcomes with multinomial logistic regression.RESULTS: We found that low stress resilience in adolescence conferred increased risks of all studied measures of addictive behaviour. After adjusting for childhood socioeconomic information, low stress resilience was associated with adult current regular smoking (relative risk ratio: 5.85, 95% CI 4.32 to 7.93), higher nicotine dependence scores (beta: 0.76, 95% CI 0.29 to 1.23), hazardous use of alcohol (>14 alcoholic drink-equivalents per week, OR: 1.72, 95% CI 1.37 to 2.16), DSM-IV criteria for alcohol dependence (OR: 1.74, 95% CI 1.35 to 2.25), and drug use (OR: 1.77, 95% CI 1.51 to 2.08). The results remained largely unchanged after further adjustments for adult educational attainment and occupation as well as for additional conscription covariates.CONCLUSION: Low stress resilience in late adolescence appears to be associated with an increased risk of disadvantageous and addictive health behaviours in adulthood.
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Ruoqing, Chen,1985-Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,Clinical Epidemiology and Biostatistics,Örebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70281 Örebro, Sweden;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden(Swepub:oru)rgcn
(författare)
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Fang, FangKarolinska Institutet
(författare)
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Valdimarsdottir, UnnurKarolinska Institutet
(författare)
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Montgomery, Scott,1961-Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Epidemiology and Public Health, University College London, London, UK; Clinical Epidemiology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden,Orebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70281 Orebro, Sweden;UCL, Dept Epidemiol & Publ Hlth, London, England;Karolinska Inst, Karolinska Univ Hosp, Clin Epidemiol Unit, Stockholm, Sweden(Swepub:oru)smy
(författare)
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Larsson, Henrik,1975-Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,Orebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70281 Orebro, Sweden;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden(Swepub:oru)hiln
(författare)
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Fall, Katja,1971-Örebro universitet,Institutionen för medicinska vetenskaper,Orebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, S-70281 Orebro, Sweden;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden(Swepub:oru)kafl
(författare)
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Örebro universitetInstitutionen för medicinska vetenskaper
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Journal of Epidemiology and Community Health: BMJ Publishing Group Ltd73:6, s. 469-5010143-005X1470-2738
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Kennedy, Beatric ...
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Ruoqing, Chen, 1 ...
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Fang, Fang
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Valdimarsdottir, ...
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Montgomery, Scot ...
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Larsson, Henrik, ...
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Fall, Katja, 197 ...
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