WFRF:(Tremblay Franco M.)
Sökning: WFRF:(Tremblay Franco M.) > Genome-wide associa...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 29841naa a2202629 4500 | |
| 001 | oai:prod.swepub.kib.ki.se:141825738 | |
| 003 | SwePub | |
| 008 | 240701s2019 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:uu-394955 | |
| 009 | oai:DiVA.org:du-30699 | |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1418257382 URI |
| 024 | 7 | a https://doi.org/10.1038/s41467-019-11576-02 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3949552 URI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:du-306992 URI |
| 040 | a (SwePub)kid (SwePub)uud (SwePub)du | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Teumer, Au Univ Med Greifswald, Inst Community Med, Greifswald, Germany;DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany4 aut |
| 245 | 1 0 | a Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria |
| 264 | c 2019-09-11 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2019 |
| 520 | a Increased levels of the urinary albumin-to-creatinine ratio (UACR) are associated with higher risk of kidney disease progression and cardiovascular events, but underlying mechanisms are incompletely understood. Here, we conduct trans-ethnic (n = 564,257) and European-ancestry specific meta-analyses of genome-wide association studies of UACR, including ancestry- and diabetes-specific analyses, and identify 68 UACR-associated loci. Genetic correlation analyses and risk score associations in an independent electronic medical records database (n = 192,868) reveal connections with proteinuria, hyperlipidemia, gout, and hypertension. Fine-mapping and trans-Omics analyses with gene expression in 47 tissues and plasma protein levels implicate genes potentially operating through differential expression in kidney (including TGFB1, MUC1, PRKCI, and OAF), and allow coupling of UACR associations to altered plasma OAF concentrations. Knockdown of OAF and PRKCI orthologs in Drosophila nephrocytes reduces albumin endocytosis. Silencing fly PRKCI further impairs slit diaphragm formation. These results generate a priority list of genes and pathways for translational research to reduce albuminuria. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
| 653 | a Hälsa och välfärd | |
| 700 | 1 | a Li, Yu Univ Freiburg, Fac Med & Med Ctr, Dept Biometry Epidemiol & Med Bioinformat, Inst Genet Epidemiol, Freiburg, Germany4 aut |
| 700 | 1 | a Ghasemi, Su Univ Med Greifswald, Inst Community Med, Greifswald, Germany;DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany4 aut |
| 700 | 1 | a Prins, BPu Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England,Geneva Univ Hosp, Serv Nephrol, Geneva, Switzerland4 aut |
| 700 | 1 | a Wuttke, Mu Univ Freiburg, Fac Med & Med Ctr, Dept Biometry Epidemiol & Med Bioinformat, Inst Genet Epidemiol, Freiburg, Germany;Univ Freiburg, Fac Med & Med Ctr, Dept Med, Renal Div, Freiburg, Germany4 aut |
| 700 | 1 | a Hermle, Tu Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA;Welch Ctr Prevent, Epidemiol & Clin Res, Baltimore, MD USA,Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands4 aut |
| 700 | 1 | a Giri, Au Vanderbilt Univ, Med Ctr,Div Quantitat Sci, Dept Obstet & Gynecol,Vanderbilt Genet Inst, Inst Med & Publ Hlth,Vanderbilt Epidemiol Ctr, Nashville, TN 37232 USA;Vanderbilt Univ, Tennessee Valley Healthcare Syst 626, Biomed Lab Res & Dev, 221 Kirkland Hall, Nashville, TN 37235 USA,Univ Med Ctr Rotterdam, Erasmus MC, Dept Internal Med, Rotterdam, Netherlands4 aut |
| 700 | 1 | a Sieber, KBu GlaxoSmithKline, Target Sci Genet, Collegeville, PA USA4 aut |
| 700 | 1 | a Qiu, CXu Univ Penn, Dept Med, Dept Genet, Renal Elect & Hypertens,Div Perelman Sch Med, Philadelphia, PA 19104 USA4 aut |
| 700 | 1 | a Kirsten, Hu Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany;Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany4 aut |
| 700 | 1 | a Tin, Au Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA;Welch Ctr Prevent, Epidemiol & Clin Res, Baltimore, MD USA4 aut |
| 700 | 1 | a Chu, AYu Merck & Co Inc, Genet, Kenilworth, NJ USA4 aut |
| 700 | 1 | a Bansal, Nu Univ Washington, Div Nephrol, Seattle, WA 98195 USA;Univ Washington, Kidney Res Inst, Seattle, WA 98195 USA4 aut |
| 700 | 1 | a Feitosa, MFu Washington Univ, Sch Med, Dept Genet, Div Stat Genom, St Louis, MO 63110 USA4 aut |
| 700 | 1 | a Wang, Lu Washington Univ, Sch Med, Dept Genet, Div Stat Genom, St Louis, MO 63110 USA4 aut |
| 700 | 1 | a Chai, JFu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore;Natl Univ Hlth Syst, Singapore, Singapore,Iceland Heart Assoc, Holtasmari 1, IS-201 Kopavogur, Iceland;Univ Iceland, Ctr Publ Hlth Sci, Sturlugata 8, IS-101 Reykjavik, Iceland4 aut |
| 700 | 1 | a Cocca, Mu IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy,Merck & Co Inc, MRL, Kenilworth, NJ USA;Celgene Inc, Cambridge, MA USA,Univ Virginia, Ctr Publ Hlth Genom, Charlottesville, VA USA4 aut |
| 700 | 1 | a Fuchsberger, Cu Univ Lubeck, Inst Biomed, Eurac Res, Bolzano, Italy4 aut |
| 700 | 1 | a Gorski, Mu Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany;Univ Regensburg, Dept Genet Epidemiol, Regensburg, Germany4 aut |
| 700 | 1 | a Hoppmann, Au Univ Freiburg, Fac Med & Med Ctr, Dept Biometry Epidemiol & Med Bioinformat, Inst Genet Epidemiol, Freiburg, Germany4 aut |
| 700 | 1 | a Horn, Ku Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany;Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany4 aut |
| 700 | 1 | a Li, Mu Univ Utah, Dept Med, Div Nephrol & Hypertens, Salt Lake City, UT 84112 USA,Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA;Univ Washington, Dept Biostat, Seattle, WA 98195 USA,Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore4 aut |
| 700 | 1 | a Marten, Ju Univ Edinburgh, Inst Genet & Mol Med, Med Res Council Human Genet Unit, Edinburgh, Midlothian, Scotland4 aut |
| 700 | 1 | a Noce, Du Univ Lubeck, Inst Biomed, Eurac Res, Bolzano, Italy4 aut |
| 700 | 1 | a Nutile, Tu CNR, Inst Genet & Biophys Adriano Buzzati Traveso, Naples, Italy4 aut |
| 700 | 1 | a Sedaghat, Su Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands,Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England;Univ Cambridge, Natl Inst Hlth Res Blood & Transplant Res Unit Do, Cambridge, England4 aut |
| 700 | 1 | a Sveinbjornsson, Gu Amgen Inc, deCODE Genet, Reykjavik, Iceland4 aut |
| 700 | 1 | a Tayo, BOu Loyola Univ Chicago, Dept Publ Hlth Sci, Maywood, IL USA4 aut |
| 700 | 1 | a Van der Most, PJu Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands,Univ Lubeck, Inst Biomed, Eurac Res, Bolzano, Italy4 aut |
| 700 | 1 | a Xu, YZu Univ Utah, Dept Med, Div Nephrol & Hypertens, Salt Lake City, UT 84112 USA,Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA;Johns Hopkins Bloomberg Sch Publ Hlth, Dept Biostat, Baltimore, MD USA4 aut |
| 700 | 1 | a Yu, Z4 aut |
| 700 | 1 | a Gerstner, Lu Univ Freiburg, Fac Med & Med Ctr, Dept Med, Renal Div, Freiburg, Germany4 aut |
| 700 | 1 | a Ärnlöv, Johan,d 1970-u Högskolan Dalarna,Karolinska Institutet,Karolinska Inst, Div Family Med & Primary Care, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden;Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden,Medicinsk vetenskap4 aut0 (Swepub:du)jan |
| 700 | 1 | a Lind, Larsu Uppsala universitet,Klinisk epidemiologi,Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol,Vanderbilt Genet Inst, Nashville, TN USA;Vanderbilt Univ, Tennessee Valley Healthcare Syst 626, Dept Vet Affairs, 221 Kirkland Hall, Nashville, TN 37235 USA4 aut0 (Swepub:uu)larslind |
| 700 | 1 | a Baptista, Du Geneva Univ Hosp, Cardiol, Geneva, Switzerland4 aut |
| 700 | 1 | a Biggs, MLu Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany;Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany4 aut |
| 700 | 1 | a Boerwinkle, Eu Univ Texas Hlth Sci Ctr Houston, Human Genet Ctr, Houston, TX 77030 USA4 aut |
| 700 | 1 | a Brenner, Hu German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany;Heidelberg Univ, Network Aging Res, Heidelberg, Germany,NIA, Lab Epidemiol & Populat Sci, Intramural Res Program, NIH, Bethesda, MD 20892 USA4 aut |
| 700 | 1 | a Burkhardt, Ru Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany;Univ Leipzig, Inst Lab Med Clin Chem & Mol Diagnost, Leipzig, Germany;Univ Hosp Regensburg, Inst Clin Chem & Lab Med, Regensburg, Germany4 aut |
| 700 | 1 | a Carroll, RJu Vanderbilt Univ, Med Ctr, Dept Biomed Informat, Nashville, TN USA,Univ Med Greifswald, Inst Physiol, Karlsburg, Germany4 aut |
| 700 | 1 | a Chee, MLu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore,Univ Freiburg, Fac Med & Med Ctr, Dept Med, Renal Div, Freiburg, Germany4 aut |
| 700 | 1 | a Chee, ML4 aut |
| 700 | 1 | a Chen, MM4 aut |
| 700 | 1 | a Cheng, CYu Natl Univ Hlth Syst, Singapore, Singapore;Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore;Duke NUS Med Sch, Ophthalmol & Visual Sci Acad Clin Program Eye ACP, Singapore, Singapore;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Ophthalmol, Singapore, Singapore4 aut |
| 700 | 1 | a Cook, JPu Univ Liverpool, Dept Biostat, Liverpool, Merseyside, England4 aut |
| 700 | 1 | a Coresh, Ju Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA4 aut |
| 700 | 1 | a Corre, Tu Univ Lausanne, Ctr Primary Care & Publ Hlth Unisante, Lausanne, Switzerland;Univ Lausanne, Dept Computat Biol, Lausanne, Switzerland;Swiss Inst Bioinformat, Lausanne, Switzerland4 aut |
| 700 | 1 | a Danesh, Ju Univ Cambridge, Sch Clin Med, Dept Publ Hlth & Primary Care, Cambridge, England4 aut |
| 700 | 1 | a de Borst, MHu Univ Groningen, Univ Med Ctr Groningen, Div Nephrol, Dept Internal Med, Groningen, Netherlands,Amgen Inc, deCODE Genet, Reykjavik, Iceland4 aut |
| 700 | 1 | a De Grandi, Au Univ Lubeck, Inst Biomed, Eurac Res, Bolzano, Italy4 aut |
| 700 | 1 | a de Mutsert, Ru Leiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands4 aut |
| 700 | 1 | a de Vries, APJu Leiden Univ, Med Ctr, Dept Internal Med, Sect Nephrol, Leiden, Netherlands,DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Munich, Germany;German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Epidemiol, Neuherberg, Germany;German Ctr Diabet Res DZD, Neuherberg, Germany,NIDDK, Div Kidney Urol & Hematol Dis, NIH, Bethesda, MD 20892 USA;Univ Maryland, Sch Med, Dept Med, Baltimore, MD 21201 USA4 aut |
| 700 | 1 | a Degenhardt, Fu Christian Albrechts Univ Kiel, Inst Clin Mol Biol, Kiel, Germany4 aut |
| 700 | 1 | a Dittrich, Ku Univ Leipzig, Hosp Children & Adolescents, Dept Women & Child Hlth, Leipzig, Germany;Univ Leipzig, Ctr Pediat Res, Leipzig, Germany,Harbor UCLA Med Ctr, Los Angeles Biomed Res Inst, Dept Pediat, Inst Translat Genom & Populat Sci, Torrance, CA 90509 USA4 aut |
| 700 | 1 | a Divers, Ju Wake Forest Sch Med, Dept Biostat & Data Sci, Winston Salem, NC USA4 aut |
| 700 | 1 | a Eckardt, KUu Charite, Intens Care Med, Berlin, Germany;Friedrich Alexander Univ Erlangen Nurnberg FAU, Dept Nephrol & Hypertens, Erlangen, Germany4 aut |
| 700 | 1 | a Ehret, Gu Geneva Univ Hosp, Cardiol, Geneva, Switzerland4 aut |
| 700 | 1 | a Endlich, Ku DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany;Univ Med Greifswald, Dept Anat & Cell Biol, Greifswald, Germany4 aut |
| 700 | 1 | a Felix, JFu Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Univ Med Ctr Rotterdam, Erasmus MC, Generat R Study Grp, Rotterdam, Netherlands;Univ Med Ctr Rotterdam, Erasmus MC, Dept Pediat, Rotterdam, Netherlands4 aut |
| 700 | 1 | a Franco, OHu Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Univ Bern, ISPM, Bern, Switzerland4 aut |
| 700 | 1 | a Franke, Au Christian Albrechts Univ Kiel, Inst Clin Mol Biol, Kiel, Germany4 aut |
| 700 | 1 | a Freedman, BIu Wake Forest Sch Med, Internal Med Sect Nephrol, Winston Salem, NC USA4 aut |
| 700 | 1 | a Freitag-Wolf, Su Univ Kiel, Univ Hosp Schleswig Holstein, Inst Med Informat & Stat, Kiel, Germany4 aut |
| 700 | 1 | a Gansevoort, RTu Univ Groningen, Univ Med Ctr Groningen, Div Nephrol, Dept Internal Med, Groningen, Netherlands4 aut |
| 700 | 1 | a Giedraitis, Vilmantasu Uppsala universitet,Geriatrik4 aut0 (Swepub:uu)vigie517 |
| 700 | 1 | a Gogele, Mu Univ Lubeck, Inst Biomed, Eurac Res, Bolzano, Italy4 aut |
| 700 | 1 | a Grundner-Culemann, Fu Univ Freiburg, Fac Med & Med Ctr, Dept Biometry Epidemiol & Med Bioinformat, Inst Genet Epidemiol, Freiburg, Germany4 aut |
| 700 | 1 | a Gudbjartsson, DFu Amgen Inc, deCODE Genet, Reykjavik, Iceland4 aut |
| 700 | 1 | a Gudnason, Vu Iceland Heart Assoc, Kopavogur, Iceland;Univ Iceland, Sch Hlth Sci, Fac Med, Reykjavik, Iceland4 aut |
| 700 | 1 | a Hamet, Pu CHUM, Montreal Univ Hosp Res Ctr, Montreal, PQ, Canada;Medpharmgene, Montreal, PQ, Canada,Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands;Univ Groningen, Univ Med Ctr Groningen, Dept Genet, Groningen, Netherlands;Netherlands Heart Inst, Durrer Ctr Cardiovasc Res, Utrecht, Netherlands4 aut |
| 700 | 1 | a Harris, TB4 aut |
| 700 | 1 | a Hicks, AAu Univ Lubeck, Inst Biomed, Eurac Res, Bolzano, Italy4 aut |
| 700 | 1 | a Holm, H4 aut |
| 700 | 1 | a Foo, VHXu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore4 aut |
| 700 | 1 | a Hwang, SJu NHLBIs Framingham Heart Study, Framingham, MA USA;NHLBI, Ctr Populat Studies, Framingham, MA USA4 aut |
| 700 | 1 | a Ikram, MAu Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands,Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England;Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England4 aut |
| 700 | 1 | a Ingelsson, Erik,d 1975-u Uppsala universitet,Science for Life Laboratory, SciLifeLab,Molekylär epidemiologi,Stanford Univ, Sch Med, Div Cardiovasc Med, Dept Med, Stanford, CA 94305 USA;Stanford Univ, Stanford Cardiovasc Inst, Stanford, CA 94305 USA;Stanford Univ, Stanford Diabet Res Ctr, Stanford, CA 94305 USA4 aut0 (Swepub:uu)ering425 |
| 700 | 1 | a Jaddoe, VWVu Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Univ Med Ctr Rotterdam, Erasmus MC, Generat R Study Grp, Rotterdam, Netherlands;Univ Med Ctr Rotterdam, Erasmus MC, Dept Pediat, Rotterdam, Netherlands4 aut |
| 700 | 1 | a Jakobsdottir, Ju Leiden Univ, Med Ctr, Dept Internal Med, Sect Nephrol, Leiden, Netherlands;Leiden Univ, Med Ctr, Einthoven Lab Expt Vasc Res, Leiden, Netherlands4 aut |
| 700 | 1 | a Josyula, NSu Geisinger Res Biomed & Translat Informat Inst, Rockville, MD USA4 aut |
| 700 | 1 | a Jung, Bu Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany4 aut |
| 700 | 1 | a Kahonen, Mu Tampere Univ Hosp, Dept Clin Physiol, Tampere, Finland;Tampere Univ, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Dept Clin Physiol, Tampere, Finland4 aut |
| 700 | 1 | a Khor, CCu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore;Agcy Sci Technol & Res, Genome Inst Singapore, Singapore, Singapore4 aut |
| 700 | 1 | a Kiess, Wu Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany;Univ Leipzig, Hosp Children & Adolescents, Dept Women & Child Hlth, Leipzig, Germany;Univ Leipzig, Ctr Pediat Res, Leipzig, Germany4 aut |
| 700 | 1 | a Koenig, Wu Tech Univ Munich, Deutsch Herzzentrum Munchen, Munich, Germany;DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Munich, Germany;Univ Ulm, Inst Epidemiol & Biostat, Ulm, Germany4 aut |
| 700 | 1 | a Korner, Au Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany;Univ Leipzig, Hosp Children & Adolescents, Dept Women & Child Hlth, Leipzig, Germany;Univ Leipzig, Ctr Pediat Res, Leipzig, Germany4 aut |
| 700 | 1 | a Kovacs, Pu Univ Leipzig, Integrated Res & Treatment Ctr Adipos Dis, Leipzig, Germany4 aut |
| 700 | 1 | a Kramer, Hu Loyola Univ Chicago, Dept Publ Hlth Sci, Maywood, IL USA;Loyola Univ Chicago, Div Nephrol & Hypertens, Chicago, IL USA4 aut |
| 700 | 1 | a Kramer, BKu Heidelberg Univ, Med Fac Mannheim, Dept Med Nephrol 5, Hypertensiol,Rheumatol,Endocrinol,Diabetol, Mannheim, Germany4 aut |
| 700 | 1 | a Kronenberg, Fu Med Univ Innsbruck, Dept Med Genet Mol & Clin Pharmacol, Div Genet Epidemiol, Innsbruck, Austria4 aut |
| 700 | 1 | a Lange, LAu Univ Colorado Denver, Sch Med, Div Biomed Informat & Personalized Med, Anschutz Med Campus, Aurora, CO USA4 aut |
| 700 | 1 | a Langefeld, CDu Wake Forest Sch Med, Dept Biostat & Data Sci, Winston Salem, NC USA4 aut |
| 700 | 1 | a Lee, JJMu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore;Natl Univ Hlth Syst, Singapore, Singapore4 aut |
| 700 | 1 | a Lehtimaki, Tu Fimlab Labs, Dept Clin Chem, Tampere, Finland;Tampere Univ, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Dept Clin Chem, Tampere, Finland4 aut |
| 700 | 1 | a Lieb, Wu Univ Kiel, Inst Epidemiol, Kiel, Germany;Univ Kiel, Biobank Popgen, Kiel, Germany4 aut |
| 700 | 1 | a Lim, SCu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore;Natl Univ Hlth Syst, Singapore, Singapore;Khoo Teck Puat Hosp, Diabetes Ctr, Singapore, Singapore,Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore;Duke NUS Med Sch, Ophthalmol & Visual Sci Acad Clin Program Eye ACP, Singapore, Singapore4 aut |
| 700 | 1 | a Lind, L4 aut |
| 700 | 1 | a Lindgren, CMu Univ Oxford, Nuffield Dept Med, Oxford, England;Broad Inst MIT & Harvard, Cambridge, MA 02142 USA,German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Independent Res Grp Clin Epidemiol, Neuherberg, Germany;Ludwig Maximilians Univ Munchen, UNIKA T Augsburg, Chair Epidemiol, Augsburg, Germany4 aut |
| 700 | 1 | a Liu, JJu Natl Univ Hlth Syst, Singapore, Singapore;Agcy Sci Technol & Res, Genome Inst Singapore, Singapore, Singapore;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore4 aut |
| 700 | 1 | a Loeffler, M4 aut |
| 700 | 1 | a Lyytikainen, LPu Fimlab Labs, Dept Clin Chem, Tampere, Finland;Tampere Univ, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Dept Clin Chem, Tampere, Finland4 aut |
| 700 | 1 | a Mahajan, Au Vanderbilt Univ, Med Ctr, Div Nephrol & Hypertens, Nashville, TN USA;Vanderbilt Univ, Tennessee Valley Healthcare Syst 626, Dept Vet Affairs, 221 Kirkland Hall, Nashville, TN 37235 USA4 aut |
| 700 | 1 | a Maranville, JC4 aut |
| 700 | 1 | a Mascalzoni, Du Univ Lubeck, Inst Biomed, Eurac Res, Bolzano, Italy4 aut |
| 700 | 1 | a McMullen, Bu Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA,Univ Washington, Dept Hlth Serv, Dept Epidemiol, Cardiovasc Hlth Res Unit,Dept Med, Seattle, WA 98195 USA;Kaiser Permanente, Washington Hlth Res Inst, Seattle, WA USA4 aut |
| 700 | 1 | a Meisinger, Cu Vanderbilt Univ, Med Ctr, Dept Biomed Informat, Nashville, TN USA4 aut |
| 700 | 1 | a Meitinger, Tu DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Munich, Germany;Helmholtz Zentrum Munchen, Inst Human Genet, Neuherberg, Germany;Tech Univ Munich, Inst Human Genet, Munich, Germany4 aut |
| 700 | 1 | a Miliku, Ku Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Univ Med Ctr Rotterdam, Erasmus MC, Generat R Study Grp, Rotterdam, Netherlands;Univ Med Ctr Rotterdam, Erasmus MC, Dept Pediat, Rotterdam, Netherlands,Univ Washington, Dept Biostat, Seattle, WA 98195 USA4 aut |
| 700 | 1 | a Mook-Kanamori, DOu Leiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands;Leiden Univ, Med Ctr, Dept Publ Hlth & Primary Care, Leiden, Netherlands,Univ Zurich, Inst Physiol, Zurich, Switzerland4 aut |
| 700 | 1 | a Muller-Nurasyid, Mu German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Genet Epidemiol, Neuherberg, Germany;LMU, Fac Med, IBE, Chair Genet Epidemiol, Munich, Germany;Hosp Ludwig Maximilians Univ LMU Munich, Dept Internal Med Cardiol 1, Munich, Germany4 aut |
| 700 | 1 | a Mychaleckyj, JC4 aut |
| 700 | 1 | a Nauck, Mu DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany;Univ Med Greifswald, Inst Clin Chem & Lab Med, Greifswald, Germany4 aut |
| 700 | 1 | a Nikus, Ku Tampere Univ Hosp, Heart Ctr, Dept Cardiol, Tampere, Finland;Tampere Univ, Fac Med & Hlth Technol, Finnish Cardiovasc Res Ctr Tampere, Dept Cardiol, Tampere, Finland4 aut |
| 700 | 1 | a Ning, Bu Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA4 aut |
| 700 | 1 | a Noordam, Ru Leiden Univ, Med Ctr, Dept Internal Med, Sect Gerontol & Geriatr, Leiden, Netherlands4 aut |
| 700 | 1 | a Connell, JOu Univ Maryland, Sch Med, Baltimore, MD 21201 USA4 aut |
| 700 | 1 | a Olafsson, Iu Landspitali Univ Hosp, Dept Clin Biochem, Reykjavik, Iceland4 aut |
| 700 | 1 | a Palmer, NDu Wake Forest Sch Med, Biochem, Winston Salem, NC USA4 aut |
| 700 | 1 | a Peters, Au Univ Liverpool, Dept Biostat, Liverpool, Merseyside, England;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England4 aut |
| 700 | 1 | a Podgornaia, AIu Merck & Co Inc, Genet, Kenilworth, NJ USA4 aut |
| 700 | 1 | a Ponte, B4 aut |
| 700 | 1 | a Poulain, Tu Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany4 aut |
| 700 | 1 | a Pramstaller, PP4 aut |
| 700 | 1 | a Rabelink, TJu Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany;Univ Leipzig, Inst Lab Med Clin Chem & Mol Diagnost, Leipzig, Germany,CHUM, Montreal Univ Hosp Res Ctr, Montreal, PQ, Canada;CRCHUM, Montreal, PQ, Canada4 aut |
| 700 | 1 | a Raffield, LMu Univ N Carolina, Dept Genet, Chapel Hill, NC 27515 USA4 aut |
| 700 | 1 | a Reilly, DFu Merck & Co Inc, Genet, Kenilworth, NJ USA4 aut |
| 700 | 1 | a Rettig, R4 aut |
| 700 | 1 | a Rheinberger, Mu Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany4 aut |
| 700 | 1 | a Rice, KM4 aut |
| 700 | 1 | a Rivadeneira, Fu Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Univ Med Ctr Rotterdam, Erasmus MC, Dept Internal Med, Rotterdam, Netherlands4 aut |
| 700 | 1 | a Runz, Hu Merck & Co Inc, MRL, Kenilworth, NJ USA;Biogen Inc, 14 Cambridge Ctr, Cambridge, MA 02142 USA4 aut |
| 700 | 1 | a Ryan, KAu Univ Maryland, Sch Med, Div Endocrinol Diabet & Nutr, Baltimore, MD 21201 USA,Univ Freiburg, Fac Med & Med Ctr, Dept Biometry Epidemiol & Med Bioinformat, Inst Genet Epidemiol, Freiburg, Germany;Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA4 aut |
| 700 | 1 | a Sabanayagam, C4 aut |
| 700 | 1 | a Saum, KUu German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany4 aut |
| 700 | 1 | a Schottker, Bu German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg, Germany;Heidelberg Univ, Network Aging Res, Heidelberg, Germany4 aut |
| 700 | 1 | a Shaffer, CM4 aut |
| 700 | 1 | a Shi, Yu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore;Duke NUS Med Sch, Ophthalmol & Visual Sci Acad Clin Program Eye ACP, Singapore, Singapore4 aut |
| 700 | 1 | a Smith, AVu Univ Iceland, Sch Hlth Sci, Fac Med, Reykjavik, Iceland4 aut |
| 700 | 1 | a Strauch, Ku German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Genet Epidemiol, Neuherberg, Germany;LMU, Fac Med, IBE, Chair Genet Epidemiol, Munich, Germany4 aut |
| 700 | 1 | a Stumvoll, Mu Univ Leipzig, Dept Endocrinol & Nephrol, Leipzig, Germany4 aut |
| 700 | 1 | a Sun, BBu Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge, England4 aut |
| 700 | 1 | a Szymczak, S4 aut |
| 700 | 1 | a Tai, ESu Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore;Natl Univ Hlth Syst, Singapore, Singapore;Natl Univ Hlth Syst, Singapore, Singapore;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore;Duke NUS Med Sch, Singapore, Singapore4 aut |
| 700 | 1 | a Tan, NYQu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore,Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA4 aut |
| 700 | 1 | a Taylor, KD4 aut |
| 700 | 1 | a Teren, Au Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany;Heart Ctr Leipzig, Leipzig, Germany4 aut |
| 700 | 1 | a Tham, YC4 aut |
| 700 | 1 | a Thiery, J4 aut |
| 700 | 1 | a Thio, CHL4 aut |
| 700 | 1 | a Thomsen, Hu German Canc Res Ctr, Div Mol Genet Epidemiol, Heidelberg, Germany4 aut |
| 700 | 1 | a Thorsteinsdottir, Uu Amgen Inc, deCODE Genet, Reykjavik, Iceland4 aut |
| 700 | 1 | a Tonjes, Au Univ Leipzig, Dept Endocrinol & Nephrol, Leipzig, Germany4 aut |
| 700 | 1 | a Tremblay, J4 aut |
| 700 | 1 | a Uitterlinden, AG4 aut |
| 700 | 1 | a Van der Harst, P4 aut |
| 700 | 1 | a Verweij, Nu Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands4 aut |
| 700 | 1 | a Vogelezang, Su Univ Med Ctr Rotterdam, Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands;Univ Med Ctr Rotterdam, Erasmus MC, Generat R Study Grp, Rotterdam, Netherlands;Univ Med Ctr Rotterdam, Erasmus MC, Dept Pediat, Rotterdam, Netherlands4 aut |
| 700 | 1 | a Volker, Uu DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germany;Univ Med Greifswald, Interfac Inst Genet & Funct Genom, Greifswald, Germany4 aut |
| 700 | 1 | a Waldenberger, Mu DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, Munich, Germany;German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Inst Epidemiol, Neuherberg, Germany;German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Res Unit Mol Epidemiol, Neuherberg, Germany4 aut |
| 700 | 1 | a Wang, Cu Agcy Sci Technol & Res, Genome Inst Singapore, Singapore, Singapore;Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Wuhan, Hubei, Peoples R China,Natl Univ Hlth Syst, Singapore, Singapore;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Ophthalmol, Singapore, Singapore4 aut |
| 700 | 1 | a Wilson, ODu Vanderbilt Univ, Med Ctr, Div Nephrol & Hypertens, Nashville, TN USA4 aut |
| 700 | 1 | a Wong, C4 aut |
| 700 | 1 | a Wong, TYu Natl Univ Hlth Syst, Singapore, Singapore;Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore;Duke NUS Med Sch, Ophthalmol & Visual Sci Acad Clin Program Eye ACP, Singapore, Singapore;Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Ophthalmol, Singapore, Singapore4 aut |
| 700 | 1 | a Yang, Q4 aut |
| 700 | 1 | a Yasuda, Mu Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore, Singapore;Tohoku Univ, Grad Sch Med, Dept Ophthalmol, Sendai, Miyagi, Japan4 aut |
| 700 | 1 | a Akilesh, Su Univ Washington, Kidney Res Inst, Seattle, WA 98195 USA;Univ Washington, Med Ctr, Anat Pathol, Seattle, WA 98195 USA,Geisinger Res, Biomed & Translat Informat Inst, Danville, PA USA4 aut |
| 700 | 1 | a Bochud, Mu Univ Lausanne, Ctr Primary Care & Publ Hlth Unisante, Lausanne, Switzerland4 aut |
| 700 | 1 | a Boger, CAu Univ Hosp Regensburg, Dept Nephrol, Regensburg, Germany;Kliniken Sudostbayern, Dept Nephrol Diabetol & Rheumatol, Traunstein, Germany4 aut |
| 700 | 1 | a Devuyst, O4 aut |
| 700 | 1 | a Edwards, TL4 aut |
| 700 | 1 | a Ho, Ku Geisinger, KHRI, Danville, PA USA;Geisinger, Dept Nephrol, Danville, PA USA4 aut |
| 700 | 1 | a Morris, AP4 aut |
| 700 | 1 | a Parsa, A4 aut |
| 700 | 1 | a Pendergrass, SA4 aut |
| 700 | 1 | a Psaty, BM4 aut |
| 700 | 1 | a Rotter, JIu Harbor UCLA Med Ctr, Los Angeles Biomed Res Inst, Dept Pediat, Inst Translat Genom & Populat Sci, Torrance, CA 90509 USA;Harbor UCLA Med Ctr, Dept Pediat, Torrance, CA 90509 USA;Harbor UCLA Med Ctr, Dept Med, Torrance, CA 90509 USA4 aut |
| 700 | 1 | a Stefansson, Ku Amgen Inc, deCODE Genet, Reykjavik, Iceland4 aut |
| 700 | 1 | a Wilson, JGu Univ Mississippi, Med Ctr, Dept Phys & Biophys, Jackson, MS 39216 USA4 aut |
| 700 | 1 | a Susztak, Ku Univ Penn, Dept Med, Dept Genet, Renal Elect & Hypertens,Div Perelman Sch Med, Philadelphia, PA 19104 USA4 aut |
| 700 | 1 | a Snieder, Hu Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands4 aut |
| 700 | 1 | a Heid, IMu Univ Regensburg, Dept Genet Epidemiol, Regensburg, Germany4 aut |
| 700 | 1 | a Scholz, Mu Univ Leipzig, Inst Med Informat Stat & Epidemiol, Leipzig, Germany;Univ Leipzig, LIFE Res Ctr Civilizat Dis, Leipzig, Germany4 aut |
| 700 | 1 | a Butterworth, AS4 aut |
| 700 | 1 | a Hung, AM4 aut |
| 700 | 1 | a Pattaro, Cu Univ Lubeck, Inst Biomed, Eurac Res, Bolzano, Italy4 aut |
| 700 | 1 | a Kottgen, A4 aut |
| 710 | 2 | a Univ Med Greifswald, Inst Community Med, Greifswald, Germany;DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Greifswald, Germanyb Univ Freiburg, Fac Med & Med Ctr, Dept Biometry Epidemiol & Med Bioinformat, Inst Genet Epidemiol, Freiburg, Germany4 org |
| 773 | 0 | t Nature communicationsd : Springer Science and Business Media LLCg 10:1, s. 4130-q 10:1<4130-x 2041-1723 |
| 856 | 4 | u https://www.nature.com/articles/s41467-019-11576-0.pdf |
| 856 | 4 | u https://doi.org/10.1038/s41467-019-11576-0y Fulltext |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1362678/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://du.diva-portal.org/smash/get/diva2:1352054/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:141825738 |
| 856 | 4 8 | u https://doi.org/10.1038/s41467-019-11576-0 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-394955 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:du-30699 |
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