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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00007867naa a2200601 4500
001oai:DiVA.org:umu-154318
003SwePub
008181217s2019 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-374210
009oai:prod.swepub.kib.ki.se:140002194
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1543182 URI
0247 a https://doi.org/10.1016/S0140-6736(18)32818-62 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3742102 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1400021942 URI
040 a (SwePub)umud (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Näslund, Ulfu Umeå universitet,Avdelningen för medicin,Arcum,Umeå Univ, Heart Ctr, Umeå, Sweden; Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden4 aut0 (Swepub:umu)ulna0002
2451 0a Visualization of asymptomatic atherosclerotic disease for optimum cardiovascular prevention (VIPVIZA) :b a pragmatic, open-label, randomised controlled trial
264 1b Elsevier,c 2019
338 a print2 rdacarrier
500 a Erratum: Näslund, U., Ng, N., Lundgren, A., Fhärm, E., Grönlund, C., Johansson, H., … Norberg, M. (2019). Visualization of asymptomatic atherosclerotic disease for optimum cardiovascular prevention (VIPVIZA) : a pragmatic, open-label, randomised controlled trial. The Lancet, 393(10167), 133–142. DOI:10.1016/S0140-6736(18)32818-6
520 a BACKGROUND: Primary prevention of cardiovascular disease often fails because of poor adherence among practitioners and individuals to prevention guidelines. We aimed to investigate whether ultrasound-based pictorial information about subclinical carotid atherosclerosis, targeting both primary care physicians and individuals, improves prevention.METHODS: Visualization of asymptomatic atherosclerotic disease for optimum cardiovascular prevention (VIPVIZA) is a pragmatic, open-label, randomised controlled trial that was integrated within the Västerbotten Intervention Programme, an ongoing population-based cardiovascular disease prevention programme in northern Sweden. Individuals aged 40, 50, or 60 years with one or more conventional risk factors were eligible to participate. Participants underwent clinical examination, blood sampling, and ultrasound assessment of carotid intima media wall thickness and plaque formation. Participants were randomly assigned 1:1 with a computer-generated randomisation list to an intervention group (pictorial representation of carotid ultrasound plus a nurse phone call to confirm understanding) or a control group (not informed). The primary outcomes, Framingham risk score (FRS) and European systematic coronary risk evaluation (SCORE), were assessed after 1 year among participants who were followed up. This study is registered with ClinicalTrials.gov, number NCT01849575.FINDINGS: 3532 individuals were enrolled between April 29, 2013, and June 7, 2016, of which 1783 were randomly assigned to the control group and 1749 were assigned to the intervention group. 3175 participants completed the 1-year follow-up. At the 1-year follow-up, FRS and SCORE differed significantly between groups (FRS 1·07 [95% CI 0·11 to 2·03, p=0·0017] and SCORE 0·16 [0·02 to 0·30, p=0·0010]). FRS decreased from baseline to the 1-year follow-up in the intervention group and increased in the control group (-0·58 [95% CI -0·86 to -0·30] vs 0·35 [0·08 to 0·63]). SCORE increased in both groups (0·13 [95% CI 0·09 to 0·18] vs 0·27 [0·23 to 0·30]).INTERPRETATION: This study provides evidence of the contributory role of pictorial presentation of silent atherosclerosis for prevention of cardiovascular disease. It supports further development of methods to reduce the major problem of low adherence to medication and lifestyle modification.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
7001 a Ng, Nawiu Umeå universitet,Epidemiologi och global hälsa,Arcum,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden4 aut0 (Swepub:umu)ngna0002
7001 a Lundgren, Anna,d 1973-u Umeå universitet,Epidemiologi och global hälsa,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden4 aut0 (Swepub:umu)anlu0244
7001 a Fhärm, Evau Umeå universitet,Allmänmedicin,Umeå Univ, Unit Family Med, Umeå, Sweden4 aut0 (Swepub:umu)evfh0001
7001 a Grönlund, Christeru Umeå universitet,Radiofysik,Umeå Univ, Dept Publ Hlth & Clin Med, Dept Radiat Sci, Umeå, Sweden4 aut0 (Swepub:umu)chgr0009
7001 a Johansson, Helene,d 1962-u Umeå universitet,Epidemiologi och global hälsa,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden4 aut0 (Swepub:umu)hejo0002
7001 a Lindahl, Berntu Umeå universitet,Yrkes- och miljömedicin,Umeå Univ, Unit Occupat & Environm Med, Umeå, Sweden4 aut0 (Swepub:umu)beli0020
7001 a Lindahl, Bertil,d 1957-u Uppsala universitet,Institutionen för medicinska vetenskaper,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)belin227
7001 a Lindvall, Kristina,d 1981-u Umeå universitet,Epidemiologi och global hälsa,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden4 aut0 (Swepub:umu)kralil01
7001 a Nilsson, Stefan K.,d 1979-u Umeå universitet,Fysiologisk kemi,Umeå Univ, Unit Physiol Chem, Dept Med Biosci, Umeå, Sweden4 aut0 (Swepub:umu)nist6501
7001 a Nordin, Mariau Umeå universitet,Institutionen för psykologi,Umeå Univ, Dept Psychol, Umeå, Sweden4 aut0 (Swepub:umu)nonmaa98
7001 a Nordin, Steven,d 1960-u Umeå universitet,Institutionen för psykologi,Umeå Univ, Dept Psychol, Umeå, Sweden4 aut0 (Swepub:umu)stno0002
7001 a Nyman, Emmau Umeå universitet,Avdelningen för medicin,Umeå Univ, Heart Ctr, Umeå, Sweden; Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden4 aut0 (Swepub:umu)emny0030
7001 a Rocklöv, Joacim,c Professor,d 1979-u Umeå universitet,Yrkes- och miljömedicin,Arcum,Umeå Univ, Unit Occupat & Environm Med, Umeå, Sweden4 aut0 (Swepub:umu)joro0003
7001 a Vanoli, Davideu Umeå universitet,Avdelningen för medicin,Umeå Univ, Heart Ctr, Umeå, Sweden; Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden4 aut0 (Swepub:umu)dava0013
7001 a Weinehall, Larsu Umeå universitet,Epidemiologi och global hälsa,Arcum,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden4 aut0 (Swepub:umu)lawe0001
7001 a Wennberg, Patrik,d 1972-u Umeå universitet,Allmänmedicin,Umeå Univ, Unit Family Med, Umeå, Sweden4 aut0 (Swepub:umu)pawe0002
7001 a Wester, Peru Karolinska Institutet,Umeå universitet,Medicin,Umeå Univ, Unit Med, Umeå, Sweden4 aut0 (Swepub:umu)pewe0002
7001 a Norberg, Margaretau Umeå universitet,Epidemiologi och global hälsa,Arcum,Umeå Univ, Unit Epidemiol & Global Hlth, Umeå, Sweden4 aut0 (Swepub:umu)mano0062
7102 a Umeå universitetb Avdelningen för medicin4 org
7730 t The Lancetd : Elsevierg 393:10167, s. 133-142q 393:10167<133-142x 0140-6736x 1474-547X
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-154318
8564 8u https://doi.org/10.1016/S0140-6736(18)32818-6
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-374210
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:140002194

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