L773:1792 0981 OR L773:1792 1015
Sökning: L773:1792 0981 OR L773:1792 1015 > Exploring reflectan...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03282naa a2200373 4500 | |
| 001 | oai:gup.ub.gu.se/328701 | |
| 003 | SwePub | |
| 008 | 240910s2022 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/3287012 URI |
| 024 | 7 | a https://doi.org/10.3892/etm.2022.113372 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Kantere, Despoina4 aut |
| 245 | 1 0 | a Exploring reflectance confocal microscopy as a non-invasive diagnostic tool for genital lichen sclerosus. |
| 264 | c 2022-04-26 | |
| 264 | 1 | b Spandidos Publications,c 2022 |
| 520 | a The diagnosis of genital lichen sclerosus (LS) is often confirmed by obtaining a skin biopsy, which can lead to unwanted complications and is uncomfortable in the sensitive genital area. Thus, there is a need of finding novel, non-invasive techniques that can rapidly and accurately diagnose LS. The present study investigated the potential for reflectance confocal microscopy (RCM) to diagnose LS compared with healthy penile skin and other common penile skin disorders in males. A total of 30 male patients, including patients with LS, nonspecific balanoposthitis, plasma cell balanitis and psoriasis, and healthy individuals were included and were subject to non-invasive RCM investigation. Prominent fiber-like structures, representing hyaline sclerosis, were observed in the RCM images for almost half of the patients. Differences between healthy penile skin and LS were confirmed by identifying the edged papillae on healthy skin and their absence or obscureness in patients with LS. Notably, RCM could detect the atypical honeycomb pattern referring to dysplasia in 1 patient with LS with penile intraepithelial neoplasia. In conclusion, the present study demonstrated that RCM can detect sclerosis in penile LS. RCM can potentially become a valuable tool for monitoring patients with LS for dysplasia providing a useful non-invasive diagnostic tool for genital disorders. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
| 653 | a laser scanning microscopy | |
| 653 | a lichen sclerosus | |
| 653 | a penile intraepitelial neoplasia | |
| 653 | a reflectance confocal microscopy | |
| 700 | 1 | a Neittaanmäki, Noorau Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för laboratoriemedicin,Department of Laboratory Medicine4 aut0 (Swepub:gu)xneino |
| 700 | 1 | a Maltese, Kristina4 aut |
| 700 | 1 | a Wennberg Larkö, Ann-Marie,d 1956u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för dermatologi och venereologi,Institute of Clinical Sciences, Department of Dermatology and Venereology4 aut0 (Swepub:gu)xwenna |
| 700 | 1 | a Tunbäck, Petra4 aut |
| 710 | 2 | a Göteborgs universitetb Institutionen för biomedicin, avdelningen för laboratoriemedicin4 org |
| 773 | 0 | t Experimental and therapeutic medicined : Spandidos Publicationsg 23:6q 23:6x 1792-0981x 1792-1015 |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/328701 |
| 856 | 4 8 | u https://doi.org/10.3892/etm.2022.11337 |
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