Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 2: Aminoglycosides/aminocyclitols: apramycin, paromomycin, neomycin and spectinomycin

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Fältnamn	Indikatorer	Metadata
000		04635naa a2200793 4500
001		oai:gup.ub.gu.se/311100
003		SwePub
008		240910s2021 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://gup.ub.gu.se/publication/3111002 URI
024	7	a https://doi.org/10.2903/j.efsa.2021.68532 DOI
040		a (SwePub)gu
041		a eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Allende, Ana4 aut
245	1 0	a Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 2: Aminoglycosides/aminocyclitols: apramycin, paromomycin, neomycin and spectinomycin
264	1	b Wiley,c 2021
520		a The specific concentrations of apramycin, paromomycin, neomycin and spectinomycin in non-target feed for food-producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in feed which have an effect in terms of growth promotion/increased yield, were assessed by EFSA in collaboration with EMA. Details of the methodology used for this assessment, associated data gaps and uncertainties, are presented in a separate document. To address antimicrobial resistance, the Feed Antimicrobial Resistance Selection Concentration (FARSC) model developed specifically for the assessment was applied. However, due to the lack of data on the parameters required to calculate the FARSC for these antimicrobials, it was not possible to conclude the assessment until further experimental data become available. To address growth promotion, data from scientific publications obtained from an extensive literature review were used. Levels in feed that showed to have an effect on growth promotion/increased yield were reported for apramycin and neomycin, whilst for paromomycin and spectinomycin, no suitable data for the assessment were available. It was recommended to carry out studies to generate the data that are required to fill the gaps which prevented the calculation of the FARSC for these four antimicrobials.
650	7	a LANTBRUKSVETENSKAPERx Veterinärmedicin0 (SwePub)4032 hsv//swe
650	7	a AGRICULTURAL SCIENCESx Veterinary Science0 (SwePub)4032 hsv//eng
653		a antimicrobial resistance
653		a apramycin
653		a food-producing animals
653		a growth promotion
653		a neomycin
653		a paromomycin
653		a spectinomycin
700	1	a Koutsoumanis, Konstantinos4 aut
700	1	a Allende, Ana4 aut
700	1	a Alvarez-Ordóñez, Avelino4 aut
700	1	a Bolton, Declan4 aut
700	1	a Bover-Cid, Sara4 aut
700	1	a Chemaly, Marianne4 aut
700	1	a Davies, Robert4 aut
700	1	a De Cesare, Alessandra4 aut
700	1	a Herman, Lieve4 aut
700	1	a Hilbert, Friederike4 aut
700	1	a Lindqvist, Roland4 aut
700	1	a Nauta, Maarten4 aut
700	1	a Ru, Giuseppe4 aut
700	1	a Simmons, Marion4 aut
700	1	a Skandamis, Panagiotis4 aut
700	1	a Suffredini, Elisabetta4 aut
700	1	a Andersson, Dan I.4 aut
700	1	a Bampidis, Vasileios4 aut
700	1	a Bengtsson-Palme, Johan,d 1985u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,CARe - Centrum för antibiotikaresistensforskning,Institute of Biomedicine, Department of Infectious Medicine,Centre for antibiotic resistance research, CARe4 aut0 (Swepub:gu)xbengg
700	1	a Bouchard, Damien4 aut
700	1	a Ferran, Aude4 aut
700	1	a Kouba, Maryline4 aut
700	1	a López Puente, Secundino4 aut
700	1	a López-Alonso, Marta4 aut
700	1	a Nielsen, Søren Saxmose4 aut
700	1	a Pechová, Alena4 aut
700	1	a Petkova, Mariana4 aut
700	1	a Girault, Sebastien4 aut
700	1	a Broglia, Alessandro4 aut
700	1	a Guerra, Beatriz4 aut
700	1	a Innocenti, Matteo Lorenzo4 aut
700	1	a Liébana, Ernesto4 aut
700	1	a López-Gálvez, Gloria4 aut
700	1	a Manini, Paola4 aut
700	1	a Stella, Pietro4 aut
700	1	a Peixe, Luisa4 aut
710	2	a Göteborgs universitetb Institutionen för biomedicin, avdelningen för infektionssjukdomar4 org
773	0	t EFSA Journald : Wileyg 19:10q 19:10x 1831-4732
856	4	u https://onlinelibrary.wiley.com/doi/pdfdirect/10.2903/j.efsa.2021.6853
856	4 8	u https://gup.ub.gu.se/publication/311100
856	4 8	u https://doi.org/10.2903/j.efsa.2021.6853

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