WFRF:(Kizer J. R.)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03474naa a2200373 4500 | |
| 001 | oai:gup.ub.gu.se/55643 | |
| 003 | SwePub | |
| 008 | 240528s2007 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/556432 URI |
| 024 | 7 | a https://doi.org/10.1111/j.1365-2796.2007.01808.x2 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Fossum, E.4 aut |
| 245 | 1 0 | a The effect of baseline physical activity on cardiovascular outcomes and new-onset diabetes in patients treated for hypertension and left ventricular hypertrophy: the LIFE study |
| 264 | 1 | b Wiley,c 2007 |
| 520 | a OBJECTIVES: Physical activity (PA) is a preventive strategy for cardiovascular disease and for managing cardiovascular risk factors. There is little information on the effectiveness of PA for the prevention of cardiovascular outcomes once cardiovascular disease is present. Thus, we studied the relationship between PA at baseline and cardiovascular events in a high-risk population. DESIGN: A prespecified analyses of observational data in a prospective, randomized hypertension study. SETTING: Losartan Intervention For Endpoint reduction in hypertension (LIFE) study. SUBJECTS: Hypertension and left ventricular hypertrophy (LVH) (n = 9,193). INTERVENTIONS: Losartan versus atenolol. MAIN OUTCOME MEASURES: Reported level of PA: never exercise, exercise 30 min twice per week at baseline and after a mean of 4.8 years of treatment with losartan- versus atenolol-based therapy. Risk reductions were calculated by level of PA for the primary composite end-point and its components cardiovascular death, stroke and myocardial infarction, and also all-cause mortality and new-onset diabetes. RESULTS: A modest level of PA (>30 min twice per week) was associated with significant reductions in risk for the primary composite end-point [adjusted hazard ratio (aHR) 0.70, P < 0.001) and its components, all-cause mortality (aHR 0.65, P < 0.001), and new-onset diabetes (aHR 0.66, P < 0.001). CONCLUSION: A modest level of self-reported PA (>30 min twice per week) in patients with hypertension and LVH in the LIFE study was associated with significant reductions in risk for the primary composite end-point and its components of cardiovascular death, stroke, and myocardial infarction, all-cause mortality, and new-onset diabetes. | |
| 700 | 1 | a Gleim, G. W.4 aut |
| 700 | 1 | a Kjeldsen, S. E.4 aut |
| 700 | 1 | a Kizer, J. R.4 aut |
| 700 | 1 | a Julius, S.4 aut |
| 700 | 1 | a Devereux, R. B.4 aut |
| 700 | 1 | a Brady, W. E.4 aut |
| 700 | 1 | a Hille, D. A.4 aut |
| 700 | 1 | a Lyle, P. A.4 aut |
| 700 | 1 | a Dahlöf, Björn,d 1953u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin,Institute of Medicine, Department of Emergeny and Cardiovascular Medicine4 aut0 (Swepub:gu)xdahbj |
| 710 | 2 | a Göteborgs universitetb Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin4 org |
| 773 | 0 | t J Intern Medd : Wileyg 262:4, s. 439-48q 262:4<439-48x 0954-6820 |
| 773 | 0 | t Journal of Internal Medicined : Wileyg 262:4, s. 439-48q 262:4<439-48x 1365-2796 |
| 856 | 4 | u http://deepblue.lib.umich.edu/bitstream/2027.42/74584/1/j.1365-2796.2007.01808.x.pdf |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/55643 |
| 856 | 4 8 | u https://doi.org/10.1111/j.1365-2796.2007.01808.x |
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- Fossum, E.
- Gleim, G. W.
- Kjeldsen, S. E.
- Kizer, J. R.
- Julius, S.
- Devereux, R. B.
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- Brady, W. E.
- Hille, D. A.
- Lyle, P. A.
- Dahlöf, Björn, 1 ...
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