Sökning: WFRF:(Kristinsson Sigurdur Y.)
> (2007-2009) >
Genetics- and Immun...
Genetics- and Immune-Related Factors in the Pathogenesis of Lymphoplasmacytic Lymphoma/Waldenstrom's Macroglobulinemia
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- Kristinsson, Sigurdur Y. (författare)
- Karolinska Institutet
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Koshiol, Jill (författare)
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Goldin, Lynn R. (författare)
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- Bjorkholm, Magnus (författare)
- Karolinska Institutet
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- Turesson, Ingemar (författare)
- Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine
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Gridley, Gloria (författare)
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McMaster, Mary L. (författare)
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- Landgren, Ola (författare)
- Karolinska Institutet
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(creator_code:org_t)
- 2009
- 2009
- Engelska.
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Ingår i: Clinical Lymphoma & Myeloma. - 1557-9190. ; 9:1, s. 23-26
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.3...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- There are emerging data to support a role for genetic and immune-related factors in the pathogenesis of lymphoplasmacytic lymphoma/Waldenstrom's macroglobulinemia. In this article, we review our recently published, large, population-based studies using data from Sweden and from United States veterans and propose mechanisms and pathways underlying our observations. We also discuss future directions for new studies designed to increase our current knowledge and to define underlying biologic mechanisms of our findings. Finally, based on novel insights on this topic, we discuss clinical implications and provide perspective on the relevance of these data for patient counseling and clinical follow-up.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- Susceptibility
- Rheumatoid arthritis
- Lymphoproliferative malignancy
- Hepatitis C virus
- Autoimmune disease
- Familial aggregation
Publikations- och innehållstyp
- kon (ämneskategori)
- ref (ämneskategori)
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