Electrical stimulation compared with tolterodine for treatment of urge/urge incontinence amongst women: a randomized controlled trial

Franzén, Karin,1958-Örebro universitet,Hälsoakademin,Örebro University Hospital, Örebro, Sweden (författare)

Electrical stimulation compared with tolterodine for treatment of urge/urge incontinence amongst women : a randomized controlled trial

Introduction and hypothesis: Few randomized controlled trials have compared electrical stimulation treatment with drug therapy. Our hypothesis was that electrical stimulation treatment in women with urgency/urge incontinence would be more efficient compared to drug treatment.Methods: Women ≥18 years of age with urgency/urge incontinence were randomized to receive either ten electrical stimulation treatments vaginally and transanally over a period of 5-7 weeks or tolterodine 4 mg orally once daily.Results: Sixty-one women completed the study. There was no significant difference between the two treatment groups in micturition rate from baseline to 6 months, mean difference, -0.40 (95% confidence interval (CI), -1.61 to 0.82), but a clearly significant difference within each group for electrical stimulation, -2.8 (95% CI, -3.7 to -1.9), and for tolterodine, -3.2 (95% CI, -4.1 to -2.4).Conclusions: Both treatments reduced the number of micturitions, but electrical stimulation was not found to be superior to tolterodine.

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Reproduktionsmedicin och gynekologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Obstetrics, Gynaecology and Reproductive Medicine hsv//eng
Electrical stimulation
pharmacological treatment
urge incontinence
Obstetrics and gynaecology
Obstetrik och gynekologi
Obstetrik och gynekologi
Obstetrics and Gynaecology

Johansson, Jan-ErikÖrebro universitet,Hälsoakademin,Örebro University Hospital, Örebro, Sweden; Ctr Assessment Med Technol, Örebro Cty Council, Örebro, Sweden(Swepub:oru)jkjn (författare)
Lauridsen, IngerDept Urol, Torsby Hosp, Torsby, Sweden (författare)
Canelid, JillDept Obstet & Gynaecol, Karlstad Hosp, Karlstad, Sweden (författare)
Heiwall, BengtDept Obstet & Gynaecol, Karlstad Hosp, Karlstad, Sweden (författare)
Nilsson, Kerstin,1953-Örebro universitet,Hälsoakademin,Örebro University Hospital, Örebro, Sweden; Ctr Assessment Med Technol, Örebro Cty Council, Örebro, Sweden(Swepub:oru)ktnn (författare)
Örebro universitetHälsoakademin (creator_code:org_t)

Ingår i:International Urogynecology JournalBerlin, Germany : Springer21:12, s. 1517-15240937-34621433-3023

Av författaren/redakt...: Franzén, Karin, ...; Johansson, Jan-E ...; Lauridsen, Inger; Canelid, Jill; Heiwall, Bengt; Nilsson, Kerstin ...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Reproduktionsmed ...

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