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Sökning: WFRF:(Sternby Eilard Malin) > Importance of resec...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005373naa a2200493 4500
001oai:DiVA.org:uu-528222
003SwePub
008240522s2024 | |||||||||||000 ||eng|
009oai:DiVA.org:liu-203564
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5282222 URI
0247 a https://doi.org/10.1093/bjsopen/zrae0352 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-2035642 URI
040 a (SwePub)uud (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Ostrand, Emilu Skane Univ Hosp, Dept Surg, SE-22185 Lund, Sweden.;Lund Univ, Dept Clin Sci Lund, Lund, Sweden.4 aut
2451 0a Importance of resection margin after resection of colorectal liver metastases in the era of modern chemotherapy :b population-based cohort study
264 1b Oxford University Press,c 2024
338 a electronic2 rdacarrier
500 a Funding Agencies|Erik och Angelica Sparres forskningsstiftelse (EO)
520 a Background Resection margin has been associated with overall survival following liver resection for colorectal liver metastasis. The aim of this study was to examine how resection margins of 0.0 mm, 0.1-0.9 mm and >= 1 mm influence overall survival in patients resected for colorectal liver metastasis in a time of modern perioperative chemotherapy and surgery. Methods Using data from the national registries Swedish Colorectal Cancer Registry and Swedish National Quality Registry for Liver, Bile Duct and Gallbladder Cancer, patients that had liver resections for colorectal liver metastasis between 2009 and 2013 were included. In patients with a narrow or unknown surgical margin the original pathological reports were re-reviewed. Factors influencing overall survival were analysed using a Cox proportional hazard model. Results A total of 754 patients had a known margin status, of which 133 (17.6%) patients had a resection margin <1 mm. The overall survival in patients with a margin of 0 mm or 0.1-0.9 mm was 42 (95% c.i. 31 to 53) and 48 (95% c.i. 35 to 62) months respectively, compared with 75 (95% c.i. 65 to 85) for patients with >= 1 mm margin, P < 0.001. Margins of 0 mm or 0.1-0.9 mm were associated with poor overall survival in the multivariable analysis, HR 1.413 (95% c.i. 1.030 to 1.939), P = 0.032, and 1.399 (95% c.i. 1.025 to 1.910), P = 0.034, respectively. Conclusions Despite modern chemotherapy the resection margin is still an important factor for the survival of patients resected for colorectal liver metastasis, and a margin of >= 1 mm is needed to achieve the best possible outcome.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
7001 a Rystedt, Jennyu Skane Univ Hosp, Dept Surg, SE-22185 Lund, Sweden.;Lund Univ, Dept Clin Sci Lund, Lund, Sweden.4 aut
7001 a Engstrand, Jennieu Karolinska Univ Hosp, Div Surg, Stockholm, Sweden.;Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Stockholm, Sweden.4 aut
7001 a Frühling, Petteru Uppsala universitet,Institutionen för kirurgiska vetenskaper,Akad Univ Hosp, Sweden; Uppsala Univ, Sweden,Akad Univ Hosp, Dept Surg, Uppsala, Sweden.4 aut0 (Swepub:uu)petfr508
7001 a Hemmingsson, Oskaru Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.4 aut
7001 a Sandström, Peru Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US,Linköping Univ Hosp, Dept Surg, Linköping, Sweden.;Linköping Univ, Dept Clin & Expt Med Sci, Linköping, Sweden.4 aut0 (Swepub:liu)persa07
7001 a Eilard, Malin Sternbyu Sahlgrens Univ Hosp, Dept Transplantat & Liver Surg, Gothenburg, Sweden.;Univ Gothenburg, Sahlgrenska Acad, Dept Clin Sci, Gothenburg, Sweden.4 aut
7001 a Tingstedt, Bobbyu Skane Univ Hosp, Dept Surg, SE-22185 Lund, Sweden.;Lund Univ, Dept Clin Sci Lund, Lund, Sweden.4 aut
7001 a Buchwald, Pamelau Skane Univ Hosp, Dept Surg, Malmö, Sweden.;Lund Univ, Dept Clin Sci Malmö, Lund, Sweden.4 aut
7102 a Skane Univ Hosp, Dept Surg, SE-22185 Lund, Sweden.;Lund Univ, Dept Clin Sci Lund, Lund, Sweden.b Karolinska Univ Hosp, Div Surg, Stockholm, Sweden.;Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Stockholm, Sweden.4 org
7730 t BJS Opend : Oxford University Pressg 8:3q 8:3x 2474-9842
8564 u https://doi.org/10.1093/bjsopen/zrae035y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1859520/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-528222
8564 8u https://doi.org/10.1093/bjsopen/zrae035
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-203564

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