WFRF:(Tarnow Peter 1963)
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Small-bowel obstruction and the effects of lidocaine, atropine and hexamethonium on inflammation and fluid losses.
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- Nellgård, Per, 1956 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för anestesiologi och intensivvård,Institute of Surgical Sciences, Department of Anaesthesiology and Intensive Care
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- Jönsson, Anders, 1959 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för ortopedi,Institute of Surgical Sciences, Department of Orthopaedics
- Bojö, L (author)
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- (creator_code:org_t)
- 1996
- 1996
- English.
- In: Acta anaesthesiologica Scandinavica. - 0001-5172. ; 40:3, s. 287-92
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- The profuse fluid losses and morbidity of patients suffering from obstructive ileus are closely related to inflammatory changes in the obstructed bowel wall. Previous experimental studies have shown that use of steroids and NSAIDs can reduce fluid losses in obstructive ileus. In the present study, we investigated the effects of lidocaine on fluid losses since local anesthetics have been shown to possess wide and potent anti-inflammatory properties. Hexamethonium and atropine were used to study the importance of the autonomic nervous system in bowel obstruction.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Keyword
- Administration
- Topical
- Anesthetics
- Local
- therapeutic use
- Animals
- Anti-Inflammatory Agents
- therapeutic use
- Atropine
- therapeutic use
- Coloring Agents
- diagnostic use
- Dehydration
- physiopathology
- prevention & control
- Enteritis
- drug therapy
- physiopathology
- prevention & control
- Evans Blue
- diagnostic use
- Extravasation of Diagnostic and Therapeutic Materials
- Ganglionic Blockers
- therapeutic use
- Hexamethonium
- therapeutic use
- Injections
- Intravenous
- Intestinal Absorption
- Intestinal Mucosa
- drug effects
- secretion
- Intestinal Obstruction
- drug therapy
- physiopathology
- prevention & control
- Intestinal Secretions
- drug effects
- metabolism
- Jejunal Diseases
- drug therapy
- physiopathology
- prevention & control
- Jejunum
- drug effects
- secretion
- Lidocaine
- therapeutic use
- Male
- Muscarinic Antagonists
- therapeutic use
- Rats
- Rats
- Sprague-Dawley
Publication and Content Type
- ref (subject category)
- art (subject category)
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