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Sökning: WFRF:(Verstappen S. M. M.) > Methodological Chal...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004727naa a2200661 4500
001oai:gup.ub.gu.se/232430
003SwePub
008240528s2015 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:132719823
024a https://gup.ub.gu.se/publication/2324302 URI
024a https://doi.org/10.1002/acr.226612 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1327198232 URI
040 a (SwePub)gud (SwePub)ki
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Verstappen, S. M. M.4 aut
2451 0a Methodological Challenges When Comparing Demographic and Clinical Characteristics of International Observational Registries
264 c 2015-11-24
264 1b Wiley,c 2015
520 a Objective. Comparisons of data from different registries can be helpful in understanding variations in many aspects of rheumatoid arthritis (RA). The study aim was to assess and improve the comparability of demographic, clinical, and comorbidity data from 5 international RA registries. Methods. Using predefined definitions, 2 subsets of patients (main cohort and subcohort) from 5 international observational registries (Consortium of Rheumatology Researchers of North America Registry [CORRONA], the Swedish Rheumatology Quality of Care Register [SRR], the Norfolk Arthritis Register [NOAR], the Institute of Rheumatology Rheumatoid Arthritis cohort [IORRA], and CORRONA International) were evaluated and compared. Patients ages >18 years with RA, and present in or recruited to the registry from January 1, 2000, were included in the main cohort. Patients from the main cohort with positive rheumatoid factor and/or erosive RA who had received >= 1 synthetic disease-modifying antirheumatic drug (DMARD), and switched to or added another DMARD, were included in the subcohort at time of treatment switch. Results. Age and sex distributions were fairly similar across the registries. The percentage of patients with a high Disease Activity Score in 28 joints score varied between main cohorts (17.5% IORRA, 18.9% CORRONA, 24.7% NOAR, 27.7% CORRONA International, and 36.8% SRR), with IORRA, CORRONA, and CORRONA International including more prevalent cases of RA; the differences were smaller for the subcohort. Prevalence of comorbidities varied across registries (e.g., coronary artery disease ranged from 1.5% in IORRA to 7.9% in SRR), partly due to the way comorbidity data were captured and general cultural differences; the pattern was similar for the subcohorts. Conclusion. Despite different inclusion criteria for the individual RA registries, it is possible to improve the comparability and interpretability of differences across RA registries by applying well-defined cohort definitions.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng
653 a RHEUMATOID-ARTHRITIS
653 a CARDIOVASCULAR RISK
653 a REVISED CRITERIA
653 a CLASSIFICATION
653 a METHOTREXATE
653 a ASSOCIATION
653 a MORTALITY
653 a OUTCOMES
653 a PEOPLE
653 a ORIGIN
700a Askling, J.u Karolinska Institutet4 aut
700a Berglind, N.4 aut
700a Franzen, S.4 aut
700a Frisell, T.u Karolinska Institutet4 aut
700a Garwood, C.4 aut
700a Greenberg, J. D.4 aut
700a Holmqvist, M.u Karolinska Institutet4 aut
700a Horne, L.4 aut
700a Lampl, K.4 aut
700a Michaud, K.4 aut
700a Nyberg, Fredrik,d 1961u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xnybef
700a Pappas, D. A.4 aut
700a Reed, G.4 aut
700a Symmons, D. P. M.4 aut
700a Tanaka, E.4 aut
700a Tran, T. N.4 aut
700a Yamanaka, H.4 aut
700a Ho, M. L.4 aut
710a Karolinska Institutetb Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa4 org
773t Arthritis Care & Researchd : Wileyg 67:12, s. 1637-1645q 67:12<1637-1645x 2151-464Xx 2151-4658
856u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acr.22661
8564 8u https://gup.ub.gu.se/publication/232430
8564 8u https://doi.org/10.1002/acr.22661
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:132719823

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